968 resultados para Unstable Angina


Relevância:

20.00% 20.00%

Publicador:

Resumo:

Although the link between macroeconomic news announcements and exchange rates is well documented in recent literature, this connection may be unstable. By using a broad set of macroeconomic news announcements and high frequency forex data for the Euro/Dollar, Pound/Dollar and Yen/Dollar from Nov 1, 2004 to Mar 31, 2014, we obtain two major findings with regards to this instability. First, many macroeconomic news announcements exhibit unstable effects with certain patterns in foreign exchange rates. These news effects may change in magnitude and even in their sign over time, over business cycles and crises within distinctive contexts. This finding is robust because the results are obtained by applying a Two-Regime Smooth Transition Regression Model, a Breakpoints Regression Model, and an Efficient Test of Parameter Instability which are all consistent with each other. Second, when we explore the source of this instability, we find that global risks and the reaction by central bank monetary policy to these risks to be possible factors causing this instability.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The problem of state estimation occurs in many applications of fluid flow. For example, to produce a reliable weather forecast it is essential to find the best possible estimate of the true state of the atmosphere. To find this best estimate a nonlinear least squares problem has to be solved subject to dynamical system constraints. Usually this is solved iteratively by an approximate Gauss–Newton method where the underlying discrete linear system is in general unstable. In this paper we propose a new method for deriving low order approximations to the problem based on a recently developed model reduction method for unstable systems. To illustrate the theoretical results, numerical experiments are performed using a two-dimensional Eady model – a simple model of baroclinic instability, which is the dominant mechanism for the growth of storms at mid-latitudes. It is a suitable test model to show the benefit that may be obtained by using model reduction techniques to approximate unstable systems within the state estimation problem.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The author contends that many of the conventions of Italian film studies derive from the conflicts and the critical vocabulary that shaped the Italian reception of neorealism in the first decade after the Second World War. Those conflicts, and that critical vocabulary, which lie at the foundation of what has been called the ‘institution of neorealism,’ established an irreconcilable binary: Cronaca and Narrativa. For the neorealists and their critics, Cronaca stood for the effort to record data faithfully, while Narrativa represented the effort to employ the shaping force of human invention in the representation of information. This essay’s first section analyzes the earliest reviews of Rossellini’s Roma città aperta alongside the contemporaneous literary debates over Cronaca and Narrativa. The second section reconsiders the reception of Pratolini’s Metello and Visconti’s Senso, which similarly centered upon the conflict between Cronaca and Narrativa. The third section proposes that the concepts which have often been employed to unify neorealism are destabilized by the Cronaca/Narrativa binary. In search of a solution to neorealism’s conceptual instability, this essay proposes more critical and purposeful appropriations of the movement’s problematic genealogy.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Process scheduling techniques consider the current load situation to allocate computing resources. Those techniques make approximations such as the average of communication, processing, and memory access to improve the process scheduling, although processes may present different behaviors during their whole execution. They may start with high communication requirements and later just processing. By discovering how processes behave over time, we believe it is possible to improve the resource allocation. This has motivated this paper which adopts chaos theory concepts and nonlinear prediction techniques in order to model and predict process behavior. Results confirm the radial basis function technique which presents good predictions and also low processing demands show what is essential in a real distributed environment.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

An experimental overview of reactions induced by the stable, but weakly-bound nuclei (6)Li, (7)Li and (9)Be, and by the exotic, halo nuclei (6)He, (8)B, (11)Be and (17)F on medium-mass targets, such as (58)Ni, (59)Co or (64)Zn, is presented. Existing data on elastic scattering, total reaction cross sections, fusion processes, breakup and transfer channels are discussed in the framework of a CDCC approach taking into account the breakup degree of freedom.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Themean value of the one-loop energy-momentum tensor in thermal QED with an electric-like background that creates particles from vacuum is calculated. The problem is essentially different from calculations of effective actions ( similar to the action of Heisenberg-Euler) in backgrounds that respect the stability of vacuum. The role of a constant electric background in the violation of both the stability of vacuum and the thermal character of particle distribution is investigated. Restrictions on the electric field and the duration over which one can neglect the back-reaction of created particles are established.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

As alternativas terapêuticas, atualmente oferecidas para o tratamento da cardiopatia isquêmica, concentram-se na abordagem das propriedades da vasculatura coronariana e seus elementos circulatórios. Dentre essas, incluem-se drogas que inibem o desenvolvimento da aterosclerose, estabilizam as lesões pré-existentes, drogas que reduzem a trombose intracoronaria, diminuem o consumo de oxigênio pelo miocárdio e intervenções que restabelecem o fluxo coronariano. No entanto, esse arsenal terapêutico se torna deficiente, em relação aos agentes cardioprotetores diretos, que têm como alvo o metabolismo das células miocárdicas. Novas terapias têm sido propostas, para diminuir a repercussão celular da isquemia, protegendo as células miocárdica das conseqüências prejudiciais do fenômeno da reperfusão, ou lesão de reperfusão, desencadeada principalmente pela ativação da glicoproteina trocadora de Na+/H+ (NHE). Essa glicoproteína tem como principal função manter a estabilidade do pH das células miocárdicas durante a isquemia, podendo de forma paradoxal precipitar necrose celular durante a reperfusão, através do acúmulo de cálcio intracelular. Dos agentes cardioprotetores com capacidade de inibir a NHE, a amilorida foi a primeira droga que mostrou essa propriedade. Recentemente, outras mais potentes surgiram, como cariporide, eniporide e zoniporide, atualmente sendo avaliadas através de ensaios clínicos. Nesta revisão, analisaremos os mecanismos envolvidos na lesão de reperfusão a nível celular e a participação da inibição NHE na proteção miocárdica. Também, revisaremos os principais estudos clínicos envolvendo os inibidores da NHE-1 e sua aplicabilidade potencial.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Objetivo - Investigar os efeitos da aplicação endocárdica do laser de hólmio em regiões isquêmicas de pacientes com angina refratária, sobre a classe funcional de angina, a tolerância ao esforço, o duplo produto, a fração de ejeção e o consumo de antianginosos. Métodos - Treze pacientes (66.10 ±12 anos) não elegíveis para angioplastia ou cirurgia, com angina refratária classe III-IV e fração de ejeção de 43,4±7,8% foram submetidos a 30-40 perfurações endocárdicas de 5 mm de profundidade com o laser de hólmio, aplicado pela via percutânea a regiões isquêmicas determinadas pela prova do Tálio 201. Cinco variáveis clínicas foram avaliadas aos 3, 6 e 12 meses. A significância estatística aos 3, 6 e 12 meses foi avaliada pelo ANOVA e pelo método proposto por Bonferroni. Resultados - Todos os procedimentos tiveram sucesso. A classe funcional de angina de base, aos 3, 6 e 12 meses era respectivamente: 3,5±0,5; 2,2±0,4; 1,7±0,5; 2,0±0,7 (P<0,001); a prova submáxima de Naughton (segundos) 374±133 (base); 518±121 (6 meses) [P=0,05]; 428±132 (12 meses) [P=0,029]; os antianginosos (mg/dia) 204,8±72,5; 204,8±72,5; 137,9±66,1; 121,7±32,7[P= 0,01]; a fração de ejeção (%) 43,4±7,8 (base); 49,0±6,9 (6 meses) [0,081] e o duplo produto (x 1000) 16,2±3,4 (base); 17,8±4,4 (6 meses); 17,5±4,4 (12 meses) [P=0,253]. Conclusão - Os dados sugerem que, no grupo estudado, a aplicação percutânea do laser de hólmio em regiões isquêmicas melhora de forma significativa a classe funcional de angina e a tolerância ao esforço, apesar da redução da medicação antianginosa.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The search which it aim was to analyze the Periodontal Disease as a risk factor for the development of the Stable Angina Pectoris. For that, 120 patients (52 blokes and 68 wenches ), ages ranging from 40 to 65 years old, and attended to the Hemodinamic´s Sector of the Natal Hospital Center, showing the historic of Angina Pectoris to accomplishment of cinecoronariografhy. Before the accomplishment of this exam, the patients were submitted to interview, to investigate the possible risk factors for the Cardiovascular diseases , and it was followed of clinical periodontal examination to evaluate the presence of Periodontal Disease. After the cinecoronariography, the patients who presented diagnosis of important arterial obstruction (above 70%) were enrolled to the case grup. However the individuals with arteries free of obstruction, or obstrution below 30%, were considered without historic of Cardiovascular disease and therefore enrolled for the control grup. The groups were paired by the variables age and gender. From the analysis of the results, a did not observed statisticment the significant association between the presence of the Periodontal Disease, probing depth, periodontal attachment level, severity and extension index of the Periodontal Disease, besides the visible plaque index (VPI) an gingival bleeding index (GBI) regarding to the existence of Stable Angina Pectoris. Nevertheless , it was identified statisticment the significant association between the sistemic arterial hypertension , seric level of total cholesterol, LDL, HDL and triglycerides, showing all of them, classic risk factors appointed by the literature. Therefore, it was conclued that Periodontal Disease did not represent association with the StableAngina Pectoris at least among the studied population

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Background: Decreased heart rate variability (HRV) is related to higher morbidity and mortality. In this study we evaluated the linear and nonlinear indices of the HRV in stable angina patients submitted to coronary angiography. Methods. We studied 77 unselected patients for elective coronary angiography, which were divided into two groups: coronary artery disease (CAD) and non-CAD groups. For analysis of HRV indices, HRV was recorded beat by beat with the volunteers in the supine position for 40 minutes. We analyzed the linear indices in the time (SDNN [standard deviation of normal to normal], NN50 [total number of adjacent RR intervals with a difference of duration greater than 50ms] and RMSSD [root-mean square of differences]) and frequency domains ultra-low frequency (ULF) ≤ 0,003 Hz, very low frequency (VLF) 0,003 - 0,04 Hz, low frequency (LF) (0.04-0.15 Hz), and high frequency (HF) (0.15-0.40 Hz) as well as the ratio between LF and HF components (LF/HF). In relation to the nonlinear indices we evaluated SD1, SD2, SD1/SD2, approximate entropy (-ApEn), α1, α2, Lyapunov Exponent, Hurst Exponent, autocorrelation and dimension correlation. The definition of the cutoff point of the variables for predictive tests was obtained by the Receiver Operating Characteristic curve (ROC). The area under the ROC curve was calculated by the extended trapezoidal rule, assuming as relevant areas under the curve ≥ 0.650. Results: Coronary arterial disease patients presented reduced values of SDNN, RMSSD, NN50, HF, SD1, SD2 and -ApEn. HF ≤ 66 ms§ssup§2§esup§, RMSSD ≤ 23.9 ms, ApEn ≤-0.296 and NN50 ≤ 16 presented the best discriminatory power for the presence of significant coronary obstruction. Conclusion: We suggest the use of Heart Rate Variability Analysis in linear and nonlinear domains, for prognostic purposes in patients with stable angina pectoris, in view of their overall impairment. © 2012 Pivatelli et al.; licensee BioMed Central Ltd.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Los documentos del Seminario fueron publicados por UNESCO en 1961 con el título: La urbanización en América Latina/Urbanization in Latin America