Three dimensional morphology and compressive behaviour of sintered biodegradable composite scaffolds

Porous poly-L-lactide acid (PLA) scaffolds are prepared using polymer sintering and porogen leaching method. Different weight fractions of the Hydroxyapatite (HA) are added to the PLA to control the acidity and degradation rate. The three dimensional morphology and surface porosity are tested using micro CT, optical microscopy and scanning electron microscopy (SEM). Results indicate that the surface porosity does not change by addition of HA. The micro Ct examinations show slight decrease in the pore size and increase in wall thickness accompanied with reduced anisotropy for the scaffolds containing HA. SEM micrographs show detectable interconnected pores for the scaffold with pure PLA. Addition of the HA results in agglomeration of the HA which blocks some of the pores. Compression tests of the scaffold identify three stages in the stress-strain curve. The addition of HA adversely affects the modulus of the scaffold at the first stage, but this was reversed for the second and third stages of the compression. The results of these tests are compared with the cellular material model. The manufactured scaffold have acceptable properties for a scaffold, however improvement to the mixing of the phases of PLA and HA is required to achieve better integrity of the composite scaffolds.

Morphology and compression behaviour of biodegradable scaffolds produced by the sintering process

Porous poly(L-lactic acid) (PLA) scaffolds of 85 per cent and 90 per cent porosity are prepared using polymer sintering and porogen leaching method. Different weight fractions of 10 per cent, 30 per cent, and 50 per cent of hydroxyapatite (HA) are added to the PLA to control the acidity and degradation rate. The three-dimensional (3D) morphology and surface porosity are tested using micro-computer tomography (micro-CT), optical microscopy, and scanning electron microscopy (SEM). Results indicate that the surface porosity does not change on the addition of HA. The micro-CT examinations show a slight decrease in the pore size and increase in the wall thickness accompanied by reduced anisotropy for the scaffolds containing HA. Scanning electron micrographs show detectable interconnected pores for the scaffold with pure PLA. Addition of the HA results in agglomeration of the HA particles and reduced leaching of the porogen. Compression tests of the scaffold identify three stages in the stress-strain curve. The addition of HA results in a reduction in the modulus of the scaffold at the first stage of elastic bending of the wall, but this is reversed for the second and third stages of collapse of the wall and densification in the compression tests. In the scaffolds with 85 per cent porosity, the addition of a high percentage of HA could result in 70 per cent decrease in stiffness in the first stage, 200 per cent increase in stiffness in the second stage, and 20 per cent increase in stiffness in the third stage. The results of these tests are compared with the Gibson cellular material model that is proposed for prediction of the behaviour of cellular material under compression. The pH and molecular weight changes are tracked for the scaffolds within a period of 35 days. The addition of HA keeps the pH in the alkaline region, which results in higher rate of degradation at an early period of observation, followed by a reduced rate of degradation later in the process. The final molecular weight is higher for the scaffolds with HA than for scaffolds of pure PLA. The manufactured scaffolds offer acceptable properties in terms of the pore size range and interconnectivity of the pores and porosity for non-load-bearing bone graft substitute; however, improvement to the mixing of the phases of PLA and HA is required to achieve better integrity of the composite scaffolds. © 2008 IMechE.

Mechanical properties of structures 3D printed with cementitious powders

The three dimensional (3D) printing technology has undergone rapid development in the last few years and it is now possible to print engineering structures. This paper presents a study of the mechanical behavior of 3D printed structures using cementitious powder. Microscopic observation reveals that the 3D printed products have a layered orthotropic microstructure, in which each layer consists of parallel strips. Compression and flexural tests were conducted to determine the mechanical properties and failure characteristics of such materials. The test results confirmed that the 3D printed structures are laminated with apparent orthotropy. Based on the experimental results, a stress-strain relationship and a failure criterion based on the maximum stress criterion for orthotropic materials are proposed for the structures of 3D printed material. Finally, a finite element analysis was conducted for a 3D printed shell structure, which shows that the printing direction has a significant influence on the load bearing capacity of the structure.

Estimation of the small strain stiffness of glacial till using geophysical methods and barometric loading response

Stiffness values in geotechnical structures can range over many orders of magnitude for relatively small operational strains. The typical strain levels where soil stiffness changes most dramatically is in the range 0.01-0.1%, however soils do not exhibit linear stress-strain behaviour at small strains. Knowledge of the in situ stiffness at small strain is important in geotechnical numerical modelling and design. The stress-strain regime of cut slopes is complex, as we have different principle stress directions at different positions along the potential failure plane. For example, loading may be primarily in extension near the toe of the slope, while compressive loading is predominant at the crest of a slope. Cuttings in heavily overconsolidated clays are known to be susceptible to progressive failure and subsequent strain softening, in which progressive yielding propagates from the toe towards the crest of the slope over time. In order to gain a better understanding of the rate of softening it would be advantageous to measure changes in small strain stiffness in the field.

Uso de la matriz extracelular como material para ingeniería de tejidos

Introducción: La evaluación de injertos vasculares de submucosa de intestino delgado para la regeneración de vasos sanguíneos ha producido una permeabilidad variable (0-100%) que ha sido concurrente con la variabilidad en las técnicas de fabricación. Metodología: Investigamos los efectos de fabricación en permeabilidad y regeneración en un diseño experimental de 22factorial que combino: 1) preservación (P) o remoción (R) de la capa estratum compactum del intestino, y 2) deshidratada (D) o hidratada (H), dentro de cuatro grupos de estudio (PD, RD, PH, RH). Los injertos fueron implantados en las Arterias Carótidas de porcinos (ID 4.5mm, N=4, 7d). Permeabilidad, trombogenicidad, reacción inflamatoria, vascularización, infiltración de fibroblastos, perfil de polarización de macrófagos y fuerza tensil biaxial fueron evaluadas. Resultados: Todos los injertos PD permanecieron permeables (4/4), pero tuvieron escasa vascularización e infiltración de fibroblastos. El grupo RD permaneció permeable (4/4), presentó una extensa vascularización e infiltración de fibroblastos, y el mayor número del fenotipo de macrófagos (M2) asociado a regeneración. El grupo RH presentó menor permeabilidad (3/4), una extensa vascularización e infiltración de fibroblastos, y un perfil dominante de M2. El grupo PH presentó el menor grado de permeabilidad, y a pesar de mayor infiltración celular que PD, exhibió un fenotipo de macrófagos dominante adverso. La elasticidad de los injertos R evolucionó de una manera similar a las Carótidas nativas (particularmente RD, mientras que los injertos P mantuvieron su rigidez inicial. Discusión: Concluimos que los parámetros de fabricación afectan drásticamente los resultados, siendo los injertos RD los que arrojaron mejores resultados.

Effect of temperature and strain rate on the compressive behaviour of supramolecular polyurethane

Supramolecular polyurethanes (SPUs) possess thermoresponsive and thermoreversible properties, and those characteristics are highly desirable in both bulk commodity and value-added applications such as adhesives, shape-memory materials, healable coatings and lightweight, impact-resistant structures (e.g. protection for mobile electronics). A better understanding of the mechanical properties, especially the rate and temperature sensitivity, of these materials are required to assess their suitability for different applications. In this paper, a newly developed SPU with tuneable thermal properties was studied, and the response of this SPU to compressive loading over strain rates from 10−3 to 104 s−1 was presented. Furthermore, the effect of temperature on the mechanical response was also demonstrated. The sample was tested using an Instron mechanical testing machine for quasi-static loading, a home-made hydraulic system for moderate rates and a traditional split Hopkinson pressure bars (SHPBs) for high strain rates. Results showed that the compression stress-strain behaviour was affected significantly by the thermoresponsive nature of SPU, but that, as expected for polymeric materials, the general trends of the temperature and the rate dependence mirror each other. However, this behaviour is more complicated than observed for many other polymeric materials, as a result of the richer range of transitions that influence the behaviour over the range of temperatures and strain rates tested.

Análise numérica e experimental do comportamento de fundações superficiais assentes em solo melhorado

O presente trabalho tem como objetivo estudar o comportamento de camadas superficiais de solo melhorado como base de fundações superficiais. Nesta pesquisa foram realizados ensaios de placa de 30 cm de diâmetro sobre camadas de solo residual compactado e de solo tratado com cimento (teor de 5% de cimento), ambas com 60 cm de espessura. O programa experimental também incluiu a retirada de amostras de campo das camadas de solo melhorado para a execução de ensaios triaxiais drenados (CID) com medida interna de deformações, a fim de obter parâmetros constitutivos para a realização de simulações numéricas. Uma comparação entre os resultados dos ensaios triaxiais com amostras retiradas em campo e moldadas em laboratório (Rohlfes Junior, 1996) é apresentada. A diferença entre os resultados dos ensaios triaxiais com amostras de campo e laboratório foi significativa para o caso das amostras de solo melhorado com cimento, tal fato é atribuído principalmente a dificuldade de mistura em campo. O Método dos Elementos Finitos foi utilizado para simular o comportamento carga x recalque das placas assentes sobre camadas de solo melhorado. O modelo Pseudo-Elástico Não Linear (Hiperbólico) foi empregado na análise numérica para modelar o comportamento dos novos materiais. Os resultados dos ensaios de placa sobre camadas de solo melhorado demonstraram que houve um aumento significativo da capacidade de suporte, além de uma redução considerável dos recalques, quando comparados ao comportamento carga x recalque do solo natural (Cudmani, 1994). A analise do comportamento de fundações superficiais assentes em solos estratificados, através de simulações numéricas, demonstrou ser eficiente para a previsão do comportamento carga x recalque das mesmas.

Estudo do comportamento de um solo mole tratado com cal, visando seu uso em fundações superficiais

Neste trabalho foi analisada a melhoria nas características de um solo mole quando tratado com cal, bem como a viabilidade técnica de se utilizar este novo material como uma camada suporte de fundações superficiais. O solo estudado classifica-se pedologicamente como Gley Húmico e a jazida localiza-se no município de Canoas/RS, às margens da BR 386. O trabalho teve as seguintes finalidades: realizar um estudo da influência dos diferentes teores de cal sobre as características tensão x deformação do solo tratado; verificar o ganho de resistência com o tempo de cura; modelar o comportamerito tensão x deformação do material tratado; realizar simulações numéricas, através do Método dos Elementos Finitos, do comportamento carga x recalque de fundações continuas flexíveis assentes sobre o novo material. Adotou-se o teor ótimo de cal (obtido pelo método de Eades & Grim, 1966) de 9% e dois valores inferiores de 7% e 5%. Realizaram-se os seguintes ensaios sobre o solo natural e as misturas de solo-cal: limites de Atterberg, compactação, granulometria, difratograma de raio X, permeabilidade (triaxial) e ensaios triaxiais adensados não drenados(CIU). Todos os ensaios foram realizados para três tempos de cura (7, 28 e 90 dias) e os corpos de prova foram curados em câmara úmida. Para modelar o comportamento tensão x deformação do solo melhorado, adotou-se o Modelo Hiperbólico e para o solo natural o Modelo Cam-Clay Modificado. O Modelo Hiperbólico foi implementado no software CRISPSO, desenvolvido na Universidade de Cambridge, Inglaterra. O software foi utilizado em um estudo paramétrico para determinar a influência do processo de estabilização no comportamento carga x recalque de fundações superficiais. Dos resultados obtidos, concluiu-se: que o método de Eades & Grim (1966) não mostrou-se adequado para determinação do teor ótimo de cal; houve, de maneira geral, melhora nas características físicas com o tratamento com cal; não houve ganho de resistência com o tempo de cura; o modelo hiperbólico representou bem o comportamento das misturas de solo cal e a colocação de uma camada de solo tratado apresenta melhoras no comportamento carga x recalque de fundações superficiais contínuas flexíveis.

Estudo do comportamento de um solo residual melhorado atraves de tecnicas mecanicas e fisico-quimicas e sua aplicacao a analise de fundacoes superficiais

O presente trabalho tem como objetivo estudar o comportamento de um solo residual melhorado através do uso de técnicas mecânicas de compactação e da adição de cimento. Complementarmente foram realizadas análises numéricas destes materiais tratados quando utilizados como base de fundações superficiais. O programa experimental incluiu a retirada de amostras intactas e de material amolgado para a execução de ensaios triaxiais saturados drenados com medida interna de deformações, a fim de estudar o comportamento do solo natural e do solo tratado, quer por compactação, quer por adição de cimento e compactação. Além disto, tais ensaios são determinantes na obtenção de parâmetros constitutivos para a realização de simulações numéricas. O Método dos Elementos Finitos foi utilizado para simular o comportamento carga versus recalque de placas assentes sobre o solo natural e sobre camadas de solo melhorado. O modelo Hiperbólico foi empregado na análise numérica para modelar o comportamento tensãodeformação dos materiais. Os resultados das simulações dos ensaios de placa sobre camadas de solo melhorado demonstraram que houve um aumento significativo da capacidade de suporte, além de uma redução considerável dos recalques, quando comparados ao comportamento do solo natural.

Plastificação de um solo cimentado curado sob tensão

A fim de avaliar a contribuição das ligações cimentantes no comportamento tensão-deformação dos solos cimentados, bem como quantificar a variação das tensões de início de plastificação e incremento de tensão de plastificação em função do índice de vazios de cura, foram realizados dezoito ensaios de compressão isotrópica em amostras artificialmente cimentadas curadas com diferentes tensões confinantes, índices de vazios e teores de cimento. As amostras foram inicialmente adensadas a várias tensões confinantes ao longo da linha de compressão normal do solo sem cimentação, simulando a formação de elementos de solos em diferentes profundidades de um depósito sedimentar cimentado. Após o adensamento, as amostras eram curadas para posterior aplicação de incrementos de tensão isotrópica. Complementarmente, dezenove ensaios triaxiais drenados foram realizados em amostras artificialmente cimentadas curadas sob diferentes tensões confinantes e índices de vazios de forma a analisar as modificações dos parâmetros de resistência, deformabilidade e plastificação em função do índice de vazios e tensão de cura. Por final, um novo modelo matemático foi proposto para simular os ensaios isotrópicos das amostras curadas com diferentes índices de vazios e teores de cura, descrevendo o comportamento teórico dos elementos de solo situados nas diferentes profundidades do depósito fictício de solo cimentado. A capacidade do modelo de simular os resultados dos ensaios isotrópicos para uma gama ampla de índice de vazios de cura e teores de cimento também foi apresentada. Comentários acerca das respostas obtidas com simulações de amostras curadas a altos e baixos índices de vazios, e solicitadas a elevadas tensões isotrópicas, também são apresentadas juntamente com uma análise dos três parâmetros adicionais requeridos pelo modelo em relação ao modelo Cam Clay: um parâmetro de medida de nível de cimentação, um parâmetro definidor do tipo de comportamento da estrutura cimentante (rígido, rígido-plástico, linear, etc.), e um parâmetro que relaciona a magnitude das tensões da estrutura cimentante com o nível de cimentação da amostra.

The Effect of Residence Time on the Tensile Properties of Superelastic and Thermal Activated Ni-Ti Orthodontic Wires

Since the 1980s, different devices based on superelastic alloys have been developed to fulfill orthodontic applications. Particularly in the last decades several researches have been carried out to evaluate the mechanical behavior of Ni-Ti alloys, including their tensile, torsion and fatigue properties. However, studies regarding the dependence of elastic properties on residence time of Ni-Ti wires in the oral cavity are scarce. Such approach is essential since metallic alloys are submitted to mechanical stresses during orthodontic treatment as well as pH and temperature fluctuations. The goal of the present contribution is to provide elastic stress-strain results to guide the orthodontic choice between martensitic thermal activated and austenitic superelastic Ni-Ti alloys. From the point of view of an orthodontist, the selection of appropriate materials and the correct maintenance of the orthodontic apparatus are essential needs during clinical treatment. The present work evaluated the elastic behavior of Ni-Ti alloy wires with diameters varying from 0.014 to 0.020 inches, submitted to hysteresis tensile tests with 8% strain. Tensile tests were performed after periods of use of 1, 2 and 3 months in the oral cavity of patients submitted to orthodontic treatment. The results from the hysteresis tests allowed to exam the strain range covered by isostress lines upon loading and unloading, as well as the residual strain after unloading for both superelastic and thermal activated Ni-Ti wires. Superelastic Ni-Ti wires exhibited higher load isostress values compared to thermal activated wires. It was found that such differences in the load isostress values can increase with increasing residence time.

Estudo do comportamento mecânico de areias artificialmente cimentadas

Soil improved with the addition of cement have been utilized as an alternative to the construction of various types of geotechnical works, almost always present economic and environmental advantages. This paper presents a study on the usage of cement in the improvement of mechanical properties of sandy soils, characteristic of the region of Natal, collected from its dunes. This research was made in order to analyze the influence of cement content, voids, and also including water immersion and confining pressure. Samples molded from cement-soil mixtures were tested for unconfined compression tests and triaxial tests. The samples had the percentage of cement mixed in 2.5%, 5% and 10% by weight. The cement agent used was the Portland Cement of High Early strength(CPV-ARI), which promoted agility to the experimental procedure for presenting a rapid gain in strenght. The void ratio used ranged from 0.7 (more compact), 0,9 and 1,1(softer). The soil under study can be considered as pure sand. In general, it can be stated that the larger the amount of cement added to the sand studied is, the greater ultimate strength will be. Likewise, as more compact the soil is, the less void ratio and more resistant it will be present. The confining pressure tends to increase the resistance of the specimens. The cementing adopted grades showed that the use of different criteria for failure did not significantly alter the stress-strain parameters for the sand studied. The angle of friction values were found within the typical range of medium and compact sands. Cementing acted in the sand providing an intercepted cohesion which increased enhancing the potential cementation. In triaxial compression tests, the sand with void ratio is equal to 0.7 and showed the expected behavior for a compact sand while the stress-strain behavior of the same sand with the void ratio of 0.9 tended to be expected for the soft sand as well

Análise tribológica das malhas multifuncionais obtidas por multicamadas

The present work consists in the analysis of tribologycal properties of basic and multifunctional knitted fabrics. This knowledge has fundamental importance for the textile industry since it can quantify, in an objective way, the tactil. The fabrics used were characterized by friction and mechanical tests for determining the viscoelastic region, wear resistance and friction coefficient of the fabrics used. The stress-strain curve was obtained by the method Kawabata, KES-FB1. Wear tests performed with the aid of equipment Martindale. The measurement of friction coefficient, two methods were used and analyzed comparatively. The first was a method already established worldwide known as KES-FB4 and the second was an innovative method called FRICTORQ, developed by the University of Minho. These two methods were compared taking into account the relative motion between the tribologycal pairs are different from each method. While the first motion is translational, the second is rotational. It was formal that the knitted had a multifunctional fabrics tribologycal performance which was better than the basic knitted fabrics, as the viscoelastic region, was laager highlighting a multifunctional structure, with greater wear resistance mainly on the back side of the knitted fabrics and lower friction coefficient. Performing a comparative analysis between two methods used to measure the friction coefficient, it was formal that both methods were consistent in terms of results. In operational terms, the FRICTORQ showed ease of operation and increased reproducibility of results

Effect of cantilever length and framework alloy on the stress distribution of mandibular-cantilevered implant-supported prostheses

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Mechanical behavior of isolated intervertebral disc

The study on several components of intervertebral joints is essential to understand the spine's degenerative mechanisms and to assess the best method for their treatment. For such study it is necessary to know the mechanical properties of the isolated intervertebral disc (ID) mechanical properties and, it is necessary to evaluate its stresses and strains. In order to assess the ID displacements, a fine, U-shaped blade was developed, over which two extensometers connected in a Wheatstone bridge were placed. The device was then tested on porcine spine ID, where compression loads were applied and the extremities displacements of the blade coupled to the intervertebral disc were measured. Stress/strain diagram, both on the compression and on the decompression phases, evidencing the non-linear nature of such relationship. With the experiment, it was possible to obtain approximate values of the longitudinal elasticity module (E) of the disc material and of the Poisson coefficient (n ). After several tests, E results are compatible with those obtained by others studies, with very simple and low-cost device. This experiments can be used for obtained others mechanical properties of isolated ID with precision and accuracy.