Portrait of Elizabeth Krakauer nee Gottschalk with pigtails; Hannover, Germany.

This portrait shows Elizabeth with pig tails. In a defiant mood, she cut them off.

Portrait of the six Gottschalk children Walter, Ursula, Freddy, Hal, Elizabeth and Kurt in garden; Hannover, Germany. Portraits Children

Front row from left to right: Walter, Ursula, and Freddy; back row from left to right: Hal, Elizabeth, and Kurt Godshaw; picture was probably taken in their backyard on Seelhorststrasse in Hannover, Germany

Therese Godshaw (Gottschalk) nee Molling reading with her daughter Elizabeth; Hannover, Germany.

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Therese Godshaw (Gottschalk) nee Molling walking with Elizabeth Krakauer nee Gottschalk; Prescott, Arizona Portraits Family

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Elizabeth Gottschalk with unidentified classmates on a field trip from Sophienschule; Hannover, Germany. Institutions; Educational; Schools; Portraits; Groups

Elizabeth Gottschalk is probably the student far left on the horse wagon

The six Gottschalk children Ursula, Elizabeth, Hal, Kurt, Freddy and Walter seated in a Strandkorb (roofed wicker beach chair); Nordeney, Germany. Portraits Children

Front row Walter (left) and Freddy; middle row Kurt (left) and Hal; back row Ursula (left) and Elizabeth

Elizabeth Gottschalk hiking in the Alps with an unidentified guide.

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Three generations of Therese Gottschalk nee Molling, her daughter Elizabeth Gottschalk and Grandmother Henny Molling; Hannover, Germany.

From left to right: Therese Gottschalk nee Molling, Elizabeth Gottschalk, Henny Molling

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic consequences independent of overall adiposity. WHR is heritable, but few genetic variants influencing this trait have been identified. We conducted a meta-analysis of 32 genome-wide association studies for WHR adjusted for body mass index (comprising up to 77,167 participants), following up 16 loci in an additional 29 studies (comprising up to 113,636 subjects). We identified 13 new loci in or near RSPO3, VEGFA, TBX15-WARS2, NFE2L3, GRB14, DNM3-PIGC, ITPR2-SSPN, LY86, HOXC13, ADAMTS9, ZNRF3-KREMEN1, NISCH-STAB1 and CPEB4 (P = 1.9 × 10−9 to P = 1.8 × 10−40) and the known signal at LYPLAL1. Seven of these loci exhibited marked sexual dimorphism, all with a stronger effect on WHR in women than men (P for sex difference = 1.9 × 10−3 to P = 1.2 × 10−13). These findings provide evidence for multiple loci that modulate body fat distribution independent of overall adiposity and reveal strong gene-by-sex interactions.

Elizabeth Krakauer nee Gottschalk conducting an experiment in a Oberprima (high school) chemistry laboratory; Sophienschule; Hannover, Germany.

This picture was taken during her last year of high school. The chemistry teacher, Professor Schmigielski was one of Elizabeth's favorite teachers.

Elizabeth Krakauer nee Gottschalk seated in a Oberprima (high school) chemistry laboratory; Sophienschule; Hannover, Germany.

This picture was taken during her last year of high school. The chemistry teacher, Professor Schmigielski was one of Elizabeth's favorite teachers.

Walter Gottschalk and Fritz Gottschalk (Papa) saying goodbye to Elizabeth and Hans Krakauer who are on board the ship Koenigstein leaving to emigrate to America; Antwerp, Belgium.

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Therese Gottschalk with her daughter Elizabeth outdoors; Marienbad.

Verso: addressed to Herrn u. Frau Louis Gottschalk; Hannover; Elizabeth Gottschalk, born 1911

"Klo-KU-BA", Hans and Elizabeth Krakauer's first marital apartment in the basement of the Jewish Hospital; Hannover, Germany Architecture; Residences; Interior

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Portrait of four generations of women: Henny Molling nee Meyerhof, Elizabeth Gottschalk, Julie Meyerhof nee Oppenheimer and Therese Gottschalk nee Molling Portraits; Family

From left to right: Henny Molling, born Meyerhof, Elizabeth Gottschalk, Julie Meyerhof born Oppenheimer, and Therese Gottschalk, born Molling.