1000 resultados para Próteses parciais fixas - Aplicação de cargas axiais e não axiais
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pós-graduação em Reabilitação Oral - FOAR
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Pós-graduação em Reabilitação Oral - FOAR
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Pós-graduação em Agronomia (Energia na Agricultura) - FCA
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The use of refrigeration and air conditioning systems is of fundamental importance when it comes to air-conditioning of environments. Also important is the use of electricity for equipments’ operation related to these systems. Due to high cost of charging for this type of energy, factors economy and efficiency occupy key roles among design parameters of a system. One of the ways to get this economy is the use of a technique called thermal storage, or cold storage, which intends to move the required loads during peak time and also their equalizing, so that the energy is transferred from the peak time to non-peak time, thereby reducing the cost of energy consumed. Cold can be stored in the form of ice or ice water. This work aims to perform a technical-economic analysis of a mall located in Vale do Paraíba checking the feasibility of deploying a thermal storage system to achieve an economy in the cost of the energy used by the establishment. Through the parameters measured by the concessionaire of energy we can get the values of energy demand and power consumed, which will serve as basis for calculation for the study. The results obtained allow the development of two alternative proposals to the current configuration, one chosen by the criteria and results presented by technical-economic and energy analysis
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This work proposes two optimization algorithms for the solution of the Berth Allocation Problem (PAB). Due to the economic development of the country, it became necessary for the improvement of means of transport, which mainly shipping. For this, you need a better system management port, you will receive a lot of ships carrying cargo. In this work the PAB is approached so that the goals are to reduce costs and time handling in ports. For this, we applied two computational techniques, genetic algorithms and optimization for cloud particles, to obtain the best results for this problem. The results obtained with each type of algorithm are compared to conclude which method is more efficient for the port system
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O uso contínuo de antifúngicos tópicos e sistêmicos no tratamento convencional de candidose oral tem resultado no aparecimento de Candida albicans resistente. Por este motivo, novas tecnologias para o desenvolvimento de drogas, como os biofármacos, constituem uma estratégia, além de inovadora devido a seu mecanismo de ação, também promissora no campo da biotecnologia. Verificou-se que esta nova tecnologia possui potencial efeito em diminuir a resistência de microrganismos, especialmente do agente etiológico da candidose bucal. A Candida albicans, agente patológico de origem fúngica, expressa diversos fatores de virulência sendo comumente encontrada na pele, cavidade oral, esôfago, trato gastrointestinal e órgão reprodutor feminino podendo acometer pessoas de idades variadas, imunologicamente comprometidas, ou que utilizam próteses dentárias. Nesse sentido, peptídeos com efeito antifúngico, produzidos por plantas, animais e microrganismos estão sendo utilizados como modelos para o desenvolvimento de novas drogas com aplicações em saúde. A Histatina 5 é um peptídeo encontrado na saliva humana com forte propriedade fungicida in vitro. Este peptídeo é extremamente rico nos aminoácidos histidina e lisina e, em pH fisiológico, possui potencial de inibição da formação do biofilme de Candida albicans, podendo ser aplicado portanto, no tratamento da candidose oral. Nesse contexto, o presente estudo consiste na obtenção de análogos da Histatina-5 com modificações em sua estrutura molecular, com o objetivo de otimizar o seu potencial terapêutico já verificado nos peptídeos da família das Histatinas. A Histatina 5SC possui o aminoácido serina C-terminal substituído pela cisteína, o qual é constituído pelo grupo sulfidrila em sua cadeia lateral, para a formação de dímeros. Os peptídeos foram desenvolvidos sinteticamente pelo método de Síntese Orgânica em Fase Sólida, utilizando-se a estratégia Fmoc e...
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pós-graduação em Ciência dos Materiais - FEIS
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Pós-graduação em Televisão Digital: Informação e Conhecimento - FAAC
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Global competitiveness has been increased significantly in the last decade and, as consequence, companies are always looking for developing better processes in supply chain operations in order to maintain their competitive costs and keep themselves in the business. Logistics operations represent a large part of the product's final cost. Transportation can represent more than fifty percent of final cost sometimes. The solutions for cutting and packing problems consist in simple and low investment actions, as enhancing the arrangement of the transported load in order to decrease both material and room wastes. As per the presented reasons, the objective of this paper is to show and analyze a real application of a mathematical model to solve a manufacturer pallet-loading problem, comparing results from the model execution and the solution proposed by the company studied. This study will not only find the best arrangement to load pallets (which will optimize storage and transportation process), but also to check the effectiveness of existing modeling in the literature. For this study a computational package was used, which consists of a modeling language GAMS with the CPLEX optimization solver and two other existing software in the market, all of them indicating that an accurate mathematical model for solving this kind of problem in a two-dimensional approach is difficult to be found, in addition to a long execution time. However, the study and the software utilization indicate that the problem would be easily solved by heuristics in a shorter execution time
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In this work, the author looks forward to develop a new method capable of incorporate the concepts of the Reliability Theory and Ruin Probability in Deep Foundations, in order to do a better quantification of the uncertainties, which is intrinsic in all geotechnical projects, meanly because we don't know all the properties of the materials that we work with. Using the methodologies of Decourt Quaresma and David Cabral, resistance surfaces have been developed utilizing the data achieved from the Standard Penetration Tests performed in the field of study, in conjecture with the loads defined in the executive project of the piles. The construction of resistance surfaces shows to be a very useful tool for decision making, no matter in which phase it is current on, projecting or execution. The surfaces were developed by Kriging (using the software Surfer® 12), making it easier to visualize the geotechnical profile of the field of study. Comparing the results, the conclusion was that a high safety factor doesn't mean higher security. It is fundamental to consider the loads and resistance of the piles in the whole field, carefully choosing the project methodology responsible to define the diameter and length of the piles