998 resultados para Mitochondria division


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A Spatial Light Modulator is used to optically demultiplex modal channels on the basis of degenerate propagation constants using a shared phase mask for all channels. This allows groups of modes to be routed to common output fibres eliminating the need for MIMO equalization to transmit 2x56Gb/s QPSK over 2km of OM2 grade 50μm core MMF. © 2012 OSA.

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We review our recent exploratory investigations on mode division multiplexing using hollow-core photonic bandgap fibers (HC-PBGFs). Compared with traditional multimode fibers, HC-PBGFs have several attractive features such as ultra-low nonlinearities, low-loss transmission window around 2 μm etc. After having discussed the potential and challenges of using HC-PBGFs as transmission fibers for mode multiplexing applications, we will report a number of recent proof-of-concept results obtained in our group using direct detection receivers. The first one is the transmission of two 10.7 Gbit/s non-return to zero (NRZ) data signals over a 30 m 7-cell HC-PBGF using the offset mode launching method. In another experiment, a short piece of 19-cell HC-PBGF was used to transmit two 20 Gbit/s NRZ channels using a spatial light modulator for precise mode excitation. Bit-error-ratio (BER) performances below the forward-error-correction (FEC) threshold limit (3.3×10-3) are confirmed for both data channels when they propagate simultaneously. © 2013 IEEE.

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Mode Division Multiplexing is performed over 2km and 8km of 50μm graded-index multimode fibre using (de)multiplex phase masks based around optical vortex modes to transmit 2x56Gbps QPSK signals without MIMO equalization. © 2013 OSA.

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MIMO DSP is employed to improve the performance of degenerate mode-group division multiplexing in 8 km of conventional GI-MMF. Compensation of the mode coupling, induced by the launch and propagation, between and inside each degenerate mode-group is investigated in order to reduce the DSP complexity. © 2013 IEEE.

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A Spatial Light Modulator is used to optically demultiplex modal channels on the basis of degenerate propagation constants using a shared phase mask for all channels. This allows groups of modes to be routed to common output fibres eliminating the need for MIMO equalization to transmit 2×56Gb/s QPSK over 2km of OM2 grade 50μm core MMF. © 2012 Optical Society of America.

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A Spatial Light Modulator is used to optically demultiplex modal channels on the basis of degenerate propagation constants using a shared phase mask for all channels. This allows groups of modes to be routed to common output fibres eliminating the need for MIMO equalization to transmit 2x56Gb/s QPSK over 2km of OM2 grade 50μm core MMF. © 2012 OSA.

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This paper demonstrates how techniques from computational holography can be employed to significantly improve the modal selectivity of phase masks used in mode division multiplexing. © 2012 OSA.

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We demonstrate quantum key distribution (QKD) with bidirectional 10 Gb/s classical data channels in a single fiber using dense wavelength division multiplexing. Record secure key rates of 2.38 Mbps and fiber distances up to 70km are achieved. Data channels are simultaneously monitored for error-free operation. The robustness of QKD is further demonstrated with a secure key rate of 445 kbps over 25km, obtained in the presence of data lasers launching conventional 0 dBm power. We discuss the fundamental limit for the QKD performance in the multiplexing environment. © 2014 AIP Publishing LLC.

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A novel method for sending MIMO wireless signals to remote antenna units over a single multimode fibre is proposed. MIMO streams are sent via different fibre modes using mode division multiplexing. Combined channel measurements of 2km MMF and a typical indoor radio environment show in principle a 2×2 MIMO link at carrier frequencies up to 6GHz. © 2012 Optical Society of America.

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We propose a new low-cost solution using orthogonal transmission of non-return-tozero and carrierless-amplitude-and-phase format data to realize a coarse OFDM transmission system. Using low bandwidth electronics and optoelectronic components, the system is demonstrated at 37.5Gb/s. © OSA/ CLEO 2011.

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This paper demonstrates how techniques from computational holography can be employed to significantly improve the modal selectivity of phase masks used in mode division multiplexing. © 2012 OSA.

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Each mode of a multimode fibre is excited using binary phase patterns on a Spatial Light Modulator and verified by observation of the near-field leaving the fibre and analysis of the step response. © 2011 OSA.

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Specific fibre modes are deliberately excited in a few-mode and multimode fibre using holography. The same system is also used to demonstrate holography's ability to detect and route individual fibre modes. © OSA/OFC/NFOEC 2011.

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Polybrominated diphenyl ethers (PBDEs) are used extensively as flame-retardants and are ubiquitous in the environment and in wildlife and human tissue. Recent studies have shown that PBDEs induce neurotoxic effects in vivo and apoptosis in vitro. However, the signaling mechanisms responsible for these events are still unclear. In this study, we investigated the action of a commercial mixture of PBDEs (pentabrominated diphenyl ether, DE-71) on a human neuroblastoma cell line, SK-N-SH. A cell viability test showed a dose-dependent increase in lactate dehydrogenase leakage and 3-(4,5-dimethylthia-zol-2-yl)-2,5-diphenyl-tetrazolium bromide reduction. Cell apoptosis was observed through morphological examination, and DNA degradation in the cell cycle and cell apoptosis were demonstrated using flow cytometry and DNA laddering. The formation of reactive oxygen species was not observed, but DE-71 was found to significantly induce caspase-3, -8, and -9 activity, which suggests that apoptosis is not induced by oxidative stress but via a caspase-dependent pathway. We further investigated the intracellular calcium ([Ca2+](i)) levels using flow cytometry and observed an increase in the intracellular Ca2+ concentration with a time-dependent trend. We also found that the N-methyl d-aspartate (NMDA) receptor antagonist MK801 (3 mu M) significantly reduced DE-71-induced cell apoptosis. The results of a Western blotting test demonstrated that DE-71 treatment increases the level of Bax translocation to the mitochondria in a dose-dependent fashion and stimulates the release of cytochrome c (Cyt c) from the mitochondria into the cytoplasm. Overall, our results indicate that DE-71 induces the apoptosis of ([Ca2+](i)) in SK-N-SH cells via Bax insertion, Cyt c release in the mitochondria, and the caspase activation pathway.

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For the first time, mode group division multiplexing is achieved in a multimode fiber link using a 2-D Hermite-Gaussian mode launch. 20 Gb/s error-free transmission is achieved over a 250 m worst-case OM1 multimode fiber link. © OSA 2014.