972 resultados para Microsoft Azure


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La tesi presenta una panoramica sull'augmented, virtual e mixed reality, descrivendone le caratteristiche e le modalità di sviluppo. Come caso di studio viene analizzato il dispositivo Microsoft Hololens, descrivendone le caratteristiche concettuali, hardware e software. Per le applicazioni di questo dispositivo viene effettuata una riprogettazione della gestione e del concetto di ologramma all'interno di un'applicazione olografica, analizzandone i motivi e i vantaggi. E' fornita una overview sui dettagli implementativi della riprogettazione al fine di chiarire ogni aspetto dell'applicazione.

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Tem-se verificado um crescente aumento da esperança média de vida e paralelamente um crescente aumento no número de doentes internados. Esta situação alerta-nos para o fato de que os sistemas de informação têm de acompanhar esta evolução, para assim adquirirem sensibilidade na tomada de decisões, quando confrontados com realidades de negócio. Outro fator relevante é que as clínicas e hospitais necessitam de sistemas de informação inovadores e economicamente fiáveis para o controlo de custos e ganhos. O projeto consistiu no desenvolvimento de um módulo designado de Gestão Hospitalar NAV para Internamento, no âmbito da área de negócio da Saúde, desenvolvido em Microsoft Dynamics NAV (MS Dynamics NAV). Sendo o MS Dynamics NAV bastante versátil, verificou-se que é possível acrescentar funcionalidades para adaptar o sistema standard às necessidades do negócio, neste caso específico do internamento na área da saúde com foco no processo administrativo e alguns processos do corpo clínico. Este módulo da Gestão Hospitalar NAV para internamento vai permitir que o administrativo possa registar novos doentes, que efetue admissões de internamento e possa gerir alguns processos do doente durante o seu internamento até ao momento da alta, como por exemplo a gestão de camas, registos de visitas aos doentes e a faturação. Neste módulo também é disponibilizado a gestão de armazém; este processo permite fazer as compras aos fornecedores para repor stocks em falta e repor o stock em falta nos pisos de internamento. Como complemento, este módulo vai permitir ao médico inserir registos clínicos aos doentes internados e dar a alta médica, para assim fechar o processo do doente no internamento.

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À medida que a sociedade evolui, também as profissões evoluem com ela. Uma profissão que tem crescido de forma notável é a de consultor na área das tecnologias de informação. De facto, há alguns anos atrás, esta profissão não tinha o relevo que tem na actualidade, pois com a evolução das tecnologias da informação, as ferramentas ao dispor das empresas diversificaram-se e como tal, a mão-de-obra vai-se especializando nestas ferramentas. As empresas, na impossibilidade de contratar mão-de-obra para instalar, manter e evoluir todas as suas ferramentas, recorrem cada vez mais à experiência de consultores externos; estes são contratados para realizar tarefas específicas que as empresas não têm capacidade de executar com os próprios recursos e a sua ligação com estas entidades termina após a conclusão destas tarefas. Cada vez mais as empresas procuram tirar o máximo partido das ferramentas informáticas à sua disposição e os sistemas de Enterprise Resource Planning não são excepção. À medida que os utilizadores vão usufruindo dos sistemas, surgem novas necessidades que, depois de colmatadas, permitem a sua optimização. Além disso, com a alteração das leis, é preciso adaptar os sistemas para que estes evoluam e possam reflectir os novos requisitos legais. Com o aumento da regulação bancária, as entidades bancárias são obrigadas a comunicar informação sobre as suas finanças ao Banco de Portugal, de modo a que o banco possa analisar a saúde financeira das entidades e emitir recomendações sobre a sua forma de actuar. Esta nova forma de comunicação será efectuada por meio de relatórios em eXtended Business Reporting Language (XBRL). Pretende-se caracterizar a profissão de consultor e apresentar alguns projectos realizados enquanto consultor numa consultora de grande dimensão.

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Con el objetivo de mejorar el rendimiento de los equipos de desarrollo de software se han definido muchas metodologías de desarrollo, entre las que se encuentran las prescriptivas y las ágiles. Pese a esto, los equipos no suelen emplear ninguna por no encontrarlas ajustadas a su contexto particular, y se van directamente a la tarea de programar. En este artículo se propone una metodología de desarrollo de software ligera y adaptada a un contexto preciso y bien definido, que alinea Microsoft Solutions Framework for Agile Software Development (MSF4ASD) con los lineamientos de gestión de proyectos presentados en la Guía del PMBOK. Además, se brindan elementos para la implementación de una plataforma Microsoft de desarrollo de software en equipo para soportarla.

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Universidade Estadual de Campinas . Faculdade de Educação Física

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Universidade Estadual de Campinas. Faculdade de Educação Física

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Universidade Estadual de Campinas . Faculdade de Educação Física

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Background: Plasmodium vivax malaria is a major public health challenge in Latin America, Asia and Oceania, with 130-435 million clinical cases per year worldwide. Invasion of host blood cells by P. vivax mainly depends on a type I membrane protein called Duffy binding protein (PvDBP). The erythrocyte-binding motif of PvDBP is a 170 amino-acid stretch located in its cysteine-rich region II (PvDBP(II)), which is the most variable segment of the protein. Methods: To test whether diversifying natural selection has shaped the nucleotide diversity of PvDBP(II) in Brazilian populations, this region was sequenced in 122 isolates from six different geographic areas. A Bayesian method was applied to test for the action of natural selection under a population genetic model that incorporates recombination. The analysis was integrated with a structural model of PvDBP(II), and T-and B-cell epitopes were localized on the 3-D structure. Results: The results suggest that: (i) recombination plays an important role in determining the haplotype structure of PvDBP(II), and (ii) PvDBP(II) appears to contain neutrally evolving codons as well as codons evolving under natural selection. Diversifying selection preferentially acts on sites identified as epitopes, particularly on amino acid residues 417, 419, and 424, which show strong linkage disequilibrium. Conclusions: This study shows that some polymorphisms of PvDBP(II) are present near the erythrocyte-binding domain and might serve to elude antibodies that inhibit cell invasion. Therefore, these polymorphisms should be taken into account when designing vaccines aimed at eliciting antibodies to inhibit erythrocyte invasion.

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Lentinula edodes, commonly called shiitake, is considered a choice edible mushroom with exotic taste and medicinal quality. L. edodes grows very well and produces a range of enzymes when cultivated on eucalyptus residues. Development of appropriate experimental procedures for recovery and determination of enzymes became a widely important cash crop. In this work, enzymes produced by L. edodes were extracted using different pH buffer and determined regarding peroxidases and proteases. Lignin peroxidase (LiP) was not detected in the extracts based on veratryl alcohol or azure B oxidation. Proteases were very low while Mn-peroxidases (MnP) predominated. The optimal pH for MnP recovery was 5.0, under agitation at 25 degrees C. The oxidation of phenol red decreased after dark-colored small compounds or ions were eliminated by dialysis. The extract of L. edodes contained components of high molecular weight, such as proteases or high polyphenol, that could be involved in the LiP inactivation. L. edodes sample previously submitted to dialysis was also joined to UP of Phanerochaete chrysosporium and a total inhibition of UP was observed. (C) 2007 Elsevier Ltd. All rights reserved.

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Ceriporiopsis subvermispora is a promising white-rot fungus for biopulping. However, the underlying biochemistry involved in lignin removal and insignificant cellulose degradation by this species is not completely understood. This paper addresses this topic focusing on the involvement of ethanol-soluble extractives and wood transformation products in the biodegradation process. Cultures containing ethanol-extracted or in natura wood chips presented similar levels of extracellular enzymes and degradation of wood components. Fe3+-reducing compounds present in undecayed Pinus taeda were rapidly diminished by fungal degradation. Lignin-degradation products released during biodegradation restored part of the Fe3+-reducing activity. However, Fe3+ reduction was ineffective in presence of 0.5 mM oxalate at pH 4.5. Fungal consumption of Fe3+-reducing compounds and secretion of oxalic acid minimized the significance of Fenton`s reaction in the initial stages of wood biotreatment. This would explain limited polysaccharide degradation by the fungus that also lacks a complete set of hydrolytic enzymes. Scientific relevance of the paper: Ceriporiopsis subvermispora is a white-rot fungus suitable for biopulping processes because it degrades lignin selectively and causes significant structural changes on the wood components during the earlier decay stages. However, the intricate mechanism to explain lignin transformation and insignificant cellulose degradation by this species remains poorly understood. Some recent evidences pointed out for lipid peroxidation reactions as all initiating process explaining lignin degradation. On the other hand, alkylitaconic acids produced by the fungus via transformations of fatty acids occurring in wood showed to prevent polysaccharide degradation in Fenton reactions. In this context, one may conclude that the involvement of native wood substances or their transformation products in the overall wood biodegradation process induced by C subvermispora is still a matter of discussion. While free and esterified fatty acids present in wood extractives may be involved in the biosynthesis of alkylitaconic acids and in lipid peroxidation reactions, some extractives and lignin degradation products can reduce Fe3+, providing Fe2+ species needed to form OH radical via Fenton`s reaction. The present study focuses on this topic by evaluating the relevance of ethanol-soluble extractives and wood transformation products on the biodegradation of P. taeda by C subvermispora. For this, solid-state cultures containing ethanol-extracted and in natura wood chips were evaluated in details for up to 4 weeks. (C) 2007 Elsevier Ltd. All rights reserved.

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The brown rot fungus Wolfiporia cocos and the selective white rot fungus Perenniporia medulla-panis produce peptides and phenolate-derivative compounds as low molecular weight Fe(3+)-reductants. Phenolates were the major compounds with Fe(3+)-reducing activity in both fungi and displayed Fe(3+)-reducing activity at pH 2.0 and 4.5 in the absence and presence of oxalic acid. The chemical structures of these compounds were identified. Together with Fe(3+) and H(2)O(2) (mediated Fenton reaction) they produced oxygen radicals that oxidized lignocellulosic polysaccharides and lignin extensively in vitro under conditions similar to those found in vivo. These results indicate that, in addition to the extensively studied Gloeophyllum trabeum-a model brown rot fungus-other brown rot fungi as well as selective white rot fungi, possess the means to promote Fenton chemistry to degrade cellulose and hemicellulose, and to modify lignin. Moreover, new information is provided, particularly regarding how lignin is attacked, and either repolymerized or solubilized depending on the type of fungal attack, and suggests a new pathway for selective white rot degradation of wood. The importance of Fenton reactions mediated by phenolates operating separately or synergistically with carbohydrate-degrading enzymes in brown rot fungi, and lignin-modifying enzymes in white rot fungi is discussed. This research improves our understanding of natural processes in carbon cycling in the environment, which may enable the exploration of novel methods for bioconversion of lignocellulose in the production of biofuels or polymers, in addition to the development of new and better ways to protect wood from degradation by microorganisms.

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As part of ACIAR project ASEM/2003/052, Improving Financial Returns to Smallholder Tree Farmers in the Philippines, plantations of timber trees in Leyte Island, the Philippines were located using a systematic survey of the island. The survey was undertaken in order to compile a database of plantations which could be used to guide the planning of project activities. In addition to recording a range of qualitative and quantitative information for each plantation, the survey spatially referenced each site using a Global Positioning System (GPS) to electronic maps of the island which were held in a Geographical Information System (GIS). Microsoft Excel and Mapsource® software were used as the software links between GPS coordinates and the GIS. Mapping of farm positions was complicated by different datums being used for maps of Leyte Island and this caused GPS positions to be displaced from equivalent positions on the map. Photos of the sites were hyperlinked to their map positions in the GIS in order to assist staff to recall site characteristics.

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The financial and economic analysis of investment projects is typically carried out using the technique of discounted cash flow (DCF) analysis. This module introduces concepts of discounting and DCF analysis for the derivation of project performance criteria such as net present value (NPV), internal rate of return (IRR) and benefit to cost (B/C) ratios. These concepts and criteria are introduced with respect to a simple example, for which calculations using MicroSoft Excel are demonstrated.

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Over the last decade, software architecture emerged as a critical issue in Software Engineering. This encompassed a shift from traditional programming towards software development based on the deployment and assembly of independent components. The specification of both the overall systems structure and the interaction patterns between their components became a major concern for the working developer. Although a number of formalisms to express behaviour and to supply the indispensable calculational power to reason about designs, are available, the task of deriving architectural designs on top of popular component platforms has remained largely informal. This paper introduces a systematic approach to derive, from CCS behavioural specifications the corresponding architectural skeletons in the Microsoft .Net framework, in the form of executable C and Cω code. The prototyping process is fully supported by a specific tool developed in Haskell