Effectiveness of improved cookstoves to reduce indoor air pollution in developing countries. The case of the cassamance natural subregion, Western Africa

The Spanish NGO "Alianza por la Solidaridad" has installed improved cookstoves in 3000 households during 2012 and 2013 to improve energy efficiency reducing fuelwood consumption and to improve in-door air quality. The type of cookstoves were Noflaye Jeeg and Noflaye Jaboot and were installed in the Cassamance Natural Subregion covering part of Senegal, The Gambia and Guinea-Bissau. The Technical University of Madrid (UPM) has conducted a field study on a sample of these households to assess the effect of improved cookstoves on kitchen air quality. Measurements of carbon monoxide (CO) and fine particle matter (PM2.5) were taken for 24-hr period before and after the installation of improved cook-stoves. The 24-hr mean CO concentrations were lower than the World Health Organization (WHO) guidelines for Guinea-Bissau but higher for Senegal and Gambia, even after the installation of improved cookstoves. As for PM2.5 concentrations, 24-hr mean were always higher than these guidelines. However, improved cookstoves produced significant reductions on 24-hr mean CO and PM2.5 concentrations in Senegal and for mean and maximum PM2.5 concentration on Gambia. Although this variability needs to be explained by further research to determine which other factors could affect indoor air pollution, the study provided a better understanding of the problem and envisaged alternatives to be implemented in fu-ture phases of the NGO project.

Effectiveness of improved cookstoves to reduce indoor air pollution in developing countries. The case of the Cassamance Natural Subregion, Western Africa

The Spanish NGO "Alianza por la Solidaridad" has installed improved cookstoves in 3000 households during 2012 and 2013 to improve energy efficiency reducing fuelwood consumption and to improve indoor air quality. The type of cookstoves were Noflaye Jeeg and Noflaye Jaboot and were installed in the Cassamance Natural Subregion covering part of Senegal, The Gambia and Guinea-Bissau. The Technical University of Madrid (UPM) has conducted a field study on a sample of these households to assess the effect of improved cookstoves on kitchen air quality. Measurements of carbon monoxide (CO) and fine particle matter (PM2.5) were taken for 24-hr period before and after the installation of improved cookstoves. The 24-hr mean CO concentrations were lower than the World Health Organization (WHO) guidelines for Guinea-Bissau but higher for Senegal and Gambia, even after the installation of improved cookstoves. As for PM2.5 concentrations, 24-hr mean were always higher than these guidelines. However, improved cookstoves produced significant reductions on 24-hr mean CO and PM2.5 concentrations in Senegal and for mean and maximum PM2.5 concentration on Gambia. Although this variability needs to be explained by further research to determine which other factors could affect indoor air pollution, the study provided a better understanding of the problem and envisaged alternatives to be implemented in future phases of the NGO project.

Molecular analysis of CaMnt1p, a mannosyl transferase important for adhesion and virulence of Candida albicans

There is an immediate need for identification of new antifungal targets in opportunistic pathogenic fungi like Candida albicans. In the past, efforts have focused on synthesis of chitin and glucan, which confer mechanical strength and rigidity upon the cell wall. This paper describes the molecular analysis of CaMNT1, a gene involved in synthesis of mannoproteins, the third major class of macromolecule found in the cell wall. CaMNT1 encodes an α-1,2-mannosyl transferase, which adds the second mannose residue in a tri-mannose oligosaccharide structure which represents O-linked mannan in C. albicans. The deduced amino acid sequence suggests that CaMnt1p is a type II membrane protein residing in a medial Golgi compartment. The absence of CaMnt1p reduced the ability of C. albicans cells to adhere to each other, to human buccal epithelial cells, and to rat vaginal epithelial cells. Both heterozygous and homozygous Camnt1 null mutants of C. albicans showed strong attenuation of virulence in guinea pig and mouse models of systemic candidosis, which, in guinea pigs, could be attributed to a decreased ability to reach and/or adhere internal organs. Therefore, correct CaMnt1p-mediated O-linked mannosylation of proteins is critical for adhesion and virulence of C. albicans.

Decoding temporally encoded sensory input by cortical oscillations and thalamic phase comparators

The temporally encoded information obtained by vibrissal touch could be decoded “passively,” involving only input-driven elements, or “actively,” utilizing intrinsically driven oscillators. A previous study suggested that the trigeminal somatosensory system of rats does not obey the bottom-up order of activation predicted by passive decoding. Thus, we have tested whether this system obeys the predictions of active decoding. We have studied cortical single units in the somatosensory cortices of anesthetized rats and guinea pigs and found that about a quarter of them exhibit clear spontaneous oscillations, many of them around whisking frequencies (≈10 Hz). The frequencies of these oscillations could be controlled locally by glutamate. These oscillations could be forced to track the frequency of induced rhythmic whisker movements at a stable, frequency-dependent, phase difference. During these stimulations, the response intensities of multiunits at the thalamic recipient layers of the cortex decreased, and their latencies increased, with increasing input frequency. These observations are consistent with thalamocortical loops implementing phase-locked loops, circuits that are most efficient in decoding temporally encoded information like that obtained by active vibrissal touch. According to this model, and consistent with our results, populations of thalamic “relay” neurons function as phase “comparators” that compare cortical timing expectations with the actual input timing and represent the difference by their population output rate.

West & North Africa, ca. 1710 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Carte de la Barbarie, le [sic] la Nigritie et del la Guinée, par Guillaume de l'Isle de l'Academie Royale des Sciences. It was published by ex officina Nicolai Visscher, ca. 1710. Scale [ca.1:9,000,000]. Covers West and North Africa. Map in French.The image inside the map neatline is georeferenced to the surface of the earth and fit to the Africa Sinusoidal projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, routes and roads, territorial boundaries, shoreline features, and more. Relief shown pictorially. Includes notes.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

West & North Africa, ca. 1730 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Carte de la Barbarie, le la Nigritie et de la Guinée, par Guill[au]me Del'Isle, de l'Academie Royale des Sciences. It was published by Chez Jean Cóvens et Corneille Mortier, Geographes ca. 1730. Scale [ca.1:9,250,000]. Covers West and North Africa. Map in French.The image inside the map neatline is georeferenced to the surface of the earth and fit to the Africa Sinusoidal projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, roads and routes, territorial boundaries, shoreline features, and more. Relief shown pictorially. Includes notes.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

North & West Africa, 1655 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: L'Afrique, ou Lybie ulterieure : ou sont le Saara, ou desert, le pays des Negres, la Guinee, et les pays circonv. tirée en partie de Sanut, et de l'Arabe de Nubie, en partie de diverses cartes veües jusques a present par le S. Sanson d'Abbeville, geog. ordre. du Roy ; I. Somer Pruthenus, sculp. It was published by Chez Pierre Mariette, rue St. Iacques a l'Esperance in 1655. Scale [ca. 1:10,500,000]. Covers portions of North and West Africa. Map in French.The image inside the map neatline is georeferenced to the surface of the earth and fit to the World Miller Cylindrical projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, territorial boundaries, shoreline features, and more. Relief shown pictorially.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

West & Central Africa, ca. 1690 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Effigies ampli Regni auriferi Guineae in Africa siti, extensum inde ad insulis Atlanticis, vulgo dictis, de Cabo Verde : ad flumen Benin, us[que], ad cujus ripam sita est Regia urbs et magna Benin, at[que] inde ad promontorium Lopi Gonsalvi, delineata per S. Rovelascum, et politioribus lineamentis figurata per Lodovicum Texeram, protocosmographum Regis Hispaniarum ; Baptista Doetechomius sculpsit ; Carolus Allardt excudit. It was published by Carolus Allardt ca. 1690. Scale [ca. 1:8,000,000]. Covers portions of West and Central Africa. Map in Latin and Portuguese.The image inside the map neatline is georeferenced to the surface of the earth and fit to the World Miller Cylindrical projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, shoreline features, and more. Includes also illustrations and text.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

West & Central Africa, ca. 1752 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Guinea propria : nec non Nigritiae vel terrae Nigrorum maxima pars : Geographis hodiernis dicta utraque Aethiopia Inferior, & huius quidem pars australis ex delineationibus Anvillianis itineri Guineensi D. de Marchais insertis secundum Leges proiectionis stereographicae Hasianae, designata & edita studio & labore Homannianorum Heredum A. 1743 = Guinée de meme que la plus grande parties du pais des Negres : appellées par les geographes modernes Ethiopie inferieure et meridionale, tirées des morceaux geographiques de Mr. d'Anville, qu'il a inseres au voyage du Chev. de Marchais, & puis dessinées suivant les loix de la nouvelle projection de feu Mr. le prof. Has, par les Heritiers d'Homan. A 1743. It was published by edita studio & labore Homannianorum Heredum ca. 1752. Scale [ca. 1:7,400,000]. Covers portions of West and Central Africa. Map in Latin.The image inside the map neatline is georeferenced to the surface of the earth and fit to the World Miller Cylindrical projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, territorial boundaries, shoreline features, and more. Relief shown pictorially. Includes also notes.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

West & Central Africa, ca. 1753 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: A new and correct map of the coast of Africa : from Cape Blanco lat. 20°40'. N. to the coast of Angola lat. 11°. S. : with explanatory notes of all the forts and settlements belonging to the several European powers, R. W. Seale, sculp. It was published by J. & P. Knapton ca. 1753. Scale [ca. 1:10,000,000]. Covers portions of West and Central Africa.The image inside the map neatline is georeferenced to the surface of the earth and fit to the World Miller Cylindrical projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, territorial claims, forts, factories, shoreline features, and more. Includes also notes, index, and inset: A separate map of the Gold Coast, upon a larger scale.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

West & Central Africa, 1809 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Charte von Senegambien und Ober-Guinea : nebst dem innern Nigritien : nach den neuesten Nachrichten entworfen. It was published by im Verl. des Geograph. Instituts in 1809. Scale [ca. 1:9,250,000]. Covers portions of West and Central Africa. Map in German.The image inside the map neatline is georeferenced to the surface of the earth and fit to the World Miller Cylindrical projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, roads, cities and other human settlements, territorial boundaries, shoreline features, and more. Relief shown pictorially. Includes also notes.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.