Catalogi codicum manuscriptorum bibliothecae Bodleianae...

Title and imprint of some of the volumes vary: pt.7,v.2, and pts.12- have imprint: Oxford Clarendon Press, 1886-19 .

Lancelot of the Laik; a Scottish metrical romance, (about 1490-1500 A.D.) re-edited from a manuscript in the Cambridge University Library,

"A loose paraphrase of not quite fourteen folios of the first three volumes of the French romance of Lancelot du Lac."--Pref.

Chronicum Scotorum. A chronicle of Irish affairs, from the earliest times to A. D. 1135; with a supplement, containing the events from 1141 to 1150; edited, with a translation,

Transcribed by Duald MacFirbis.

The annals of Loch Cé : a chronicle of Irish affairs from A.D. 1014 to A.D. 1590 /

"Owner and part compiler, Brian MacDermot"--Pref.

The episcopal succession in England, Scotland and Ireland A.D. 1400 to 1875, with appointments to monasteries and extracts from consistorial acts taken from mss. in public and private libraries in Rome, Florence, Bologna, Ravenna and Paris,

"Additions and corrections" to v. I-III: v. III, p. [477]-522.

[Pamphlets]

no.1 The Railroad question. 1919?--no.2 Labor and reconstruction. 1919?--no.3 Education. 1919?--no.4 Buffer employment, land, housing. 1919?--no.5 New marketing systems, the farmer and reconstruction. 1919?--no.6 International. 1919?--no.7 Popular government. 1919?--no.8 Kent, William. Democracy and efficiency. 1913.--no.9 King, Judson. The state-wide initiative and referendum. 1917.--no.10 Vrooman, C.S. Initiative and referendum in Switzerland. 1913.--no.11 Haynes, J.R. Direct government in California. 1917.--no.12 Lewis, W.D. Recall of judicial decisions in state constitutional question.--no.13 American federation of labor. Executive council. Initiative, referendum and recall. [1913?]--no. 14 Thieme, T.F. A new state constitution for Indiana. 1914?--no.15 Montague, R.W. The Oregon system at work. 1914?--no. 16 Committee to inquire into the status of democracy. [1910?]--no. 17 National popular government league, Washington, D.C. The first year and a look ahead. 1915?--no. 18 Committee to inquire into the status of democracy. The confusion of property with privilege. [1910]--no. 19 United States. Congress. Senate. Committee on privileges and elections. Publicity and control of campaign contributions and disbursements. [1917]--no. 20 Bettman, Alfred and Hale, Swinburne. Do we need more sedition laws? [1902]--no. 21 Johnson, L.J. The preferential ballot as a substitute for the direct primary. 1915.

The Roman empire: essays on the constitutional history from the accession of Domitian (81 A. D.) to the retirement of Nicephorus III (1081 A.D.).

Mode of access: Internet.

Botanical expeditions. Col. J.C. Frémont. Col. W.H. Emory. Howard Stansbury. Jno. Torrey. 1843-8.

[No. 1] is extracted from J.C. Frémont. Report of exploring expedition to the Rocky Mountains in the year 1842; [no. 2-3] from U.S. Engineer dept. Notes of a military reconnoissance from Fort Leavenworth, in Missouri, to San Diego, in California ... By Lieut. Col. W.H. Emory; [no. 4] from U.S. Engineer dept. Exploration and survey of the valley of the Great Salt Lake in Utah.

Alpine plants,

"In presenting the accompanying work ... it should be mentioned that M. Graf ... died before he had been able to complete it, the thread being then taken up by his successor, M. Petrasch."--Pref.

Lord Milner's work in South Africa : from its commencement in 1897 to the peace of Vereeniging in 1902 containing hitherto unpublished information /

"First edition, November 1906. Reprinted before publication."

Proteolytic activation of Chlamydia trachomatis HTRA is mediated by PDZ1 domain interactions with protease domain loops L3 and LC and beta strand β5

Chlamydia trachomatis is a bacterial pathogen responsible for one of the most prevalent sexually transmitted infections worldwide. Its unique development cycle has limited our understanding of its pathogenic mechanisms. However, CtHtrA has recently been identified as a potential C. trachomatis virulence factor. CtHtrA is a tightly regulated quality control protein with a monomeric structural unit comprised of a chymotrypsin-like protease domain and two PDZ domains. Activation of proteolytic activity relies on the C-terminus of the substrate allosterically binding to the PDZ1 domain, which triggers subsequent conformational change and oligomerization of the protein into 24-mers enabling proteolysis. This activation is mediated by a cascade of precise structural arrangements, but the specific CtHtrA residues and structural elements required to facilitate activation are unknown. Using in vitro analysis guided by homology modeling, we show that the mutation of residues Arg362 and Arg224, predicted to disrupt the interaction between the CtHtrA PDZ1 domain and loop L3, and between loop L3 and loop LD, respectively, are critical for the activation of proteolytic activity. We also demonstrate that mutation to residues Arg299 and Lys160, predicted to disrupt PDZ1 domain interactions with protease loop LC and strand β5, are also able to influence proteolysis, implying their involvement in the CtHtrA mechanism of activation. This is the first investigation of protease loop LC and strand β5 with respect to their potential interactions with the PDZ1 domain. Given their high level of conservation in bacterial HtrA, these structural elements may be equally significant in the activation mechanism of DegP and other HtrA family members.

Low temperature pretreatment of sugarcane bagasse at atmospheric pressure using mixtures of ethylene carbonate and ethylene glycol

A low temperature lignocellulose pretreatment process was developed using acid-catalysed mixtures of alkylene carbonate and alkylene glycol. Pretreatment of sugarcane bagasse with mixtures of ethylene carbonate (EC) and ethylene glycol (EG) was more effective than that with mixtures of propylene carbonate (PC) and propylene glycol (PG). These mixtures were more effective than the individual components in making bagasse cellulose more amenable to cellulase digestion. Glucan digestibilities of ≥87% could be achieved with a wide range of EC to EG ratios from 9:1 to 1:1 (w/w). Pretreatment of bagasse by the EC/EG mixture with a ratio of 4:1 in the presence of 1.2% H2SO4 at 90 °C for 30 min led to the highest glucan enzymatic digestibility of 93%. The high glucan digestibilities obtained under these acidic conditions were due to (a) the ability of alkylene carbonate to cause significant biomass size reduction, (b) the ability of alkylene glycol to cause biomass defibrillation, (c) the ability of alkylene carbonate and alkylene glycol to remove xylan and lignin, and (d) the magnified above attributes in the mixtures of alkylene carbonate and alkylene glycol.