521 resultados para Cardano, Girolamo.
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Viñeta en port
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Viñeta en port
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Marca tip. en port
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Brefeldin A, a fungal metabolite that inhibits membrane transport, induces the mono(ADP-ribosyl)ation of two cytosolic proteins of 38 and 50 kDa as judged by SDS/PAGE. The 38-kDa substrate has been previously identified as glyceraldehyde-3-phosphate dehydrogenase (GAPDH). We report that the 50-kDa BFA-induced ADP-ribosylated substrate (BARS-50) has native forms of 170 and 130 kDa, as determined by gel filtration of rat brain cytosol, indicating that BARS-50 might exist as a multimeric complex. BARS-50 can bind GTP, as indicated by blot-overlay studies with [alpha-32P]GTP and by photoaffinity labeling with guanosine 5'-[gamma-32P] [beta,gamma-(4-azidoanilido)]triphosphate. Moreover, ADP-ribosylation of BARS-50 was completely inhibited by the beta gamma subunit complex of G proteins, while the ADP-ribosylation of GAPDH was unmodified, indicating that this effect was due to an interaction of the beta gamma complex with BARS-50, rather than with the ADP-ribosylating enzyme. Two-dimensional gel electrophoresis and immunoblot analysis shows that BARS-50 is a group of closely related proteins that appear to be different from all the known GTP-binding proteins.
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Inscripción en ángulo derecho: "2"
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Reprint: Rassegna Nazionale (Firenze : Ufficio della Rassegna Nazionale), anno 12, fasc. 478.
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The plates are engraved by A. Rivelanti and Girolamo Carattoni.
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Includes index.
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Mode of access: Internet.
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Reprint of the ed. published in Venice in 1885.
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Guido Cavalcanti.-Fra Giocondo.-Girolamo Beniviene.-Vittorio Alfieri.
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Mode of access: Internet.
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Corrigenda: B3-B4r. Register: B4r.
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Índice.
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Mode of access: Internet.