Deciphering a neural code for vision

Deciphering the information that eyes, ears, and other sensory organs transmit to the brain is important for understanding the neural basis of behavior. Recordings from single sensory nerve cells have yielded useful insights, but single neurons generally do not mediate behavior; networks of neurons do. Monitoring the activity of all cells in a neural network of a behaving animal, however, is not yet possible. Taking an alternative approach, we used a realistic cell-based model to compute the ensemble of neural activity generated by one sensory organ, the lateral eye of the horseshoe crab, Limulus polyphemus. We studied how the neural network of this eye encodes natural scenes by presenting to the model movies recorded with a video camera mounted above the eye of an animal that was exploring its underwater habitat. Model predictions were confirmed by simultaneously recording responses from single optic nerve fibers of the same animal. We report here that the eye transmits to the brain robust “neural images” of objects having the size, contrast, and motion of potential mates. The neural code for such objects is not found in ambiguous messages of individual optic nerve fibers but rather in patterns of coherent activity that extend over small ensembles of nerve fibers and are bound together by stimulus motion. Integrative properties of neurons in the first synaptic layer of the brain appear well suited to detecting the patterns of coherent activity. Neural coding by this relatively simple eye helps explain how horseshoe crabs find mates and may lead to a better understanding of how more complex sensory organs process information.

Integrated fossil and molecular data reconstruct bat echolocation

Molecular and morphological data have important roles in illuminating evolutionary history. DNA data often yield well resolved phylogenies for living taxa, but are generally unattainable for fossils. A distinct advantage of morphology is that some types of morphological data may be collected for extinct and extant taxa. Fossils provide a unique window on evolutionary history and may preserve combinations of primitive and derived characters that are not found in extant taxa. Given their unique character complexes, fossils are critical in documenting sequences of character transformation over geologic time and may elucidate otherwise ambiguous patterns of evolution that are not revealed by molecular data alone. Here, we employ a methodological approach that allows for the integration of molecular and paleontological data in deciphering one of the most innovative features in the evolutionary history of mammals—laryngeal echolocation in bats. Molecular data alone, including an expanded data set that includes new sequences for the A2AB gene, suggest that microbats are paraphyletic but do not resolve whether laryngeal echolocation evolved independently in different microbat lineages or evolved in the common ancestor of bats and was subsequently lost in megabats. When scaffolds from molecular phylogenies are incorporated into parsimony analyses of morphological characters, including morphological characters for the Eocene taxa Icaronycteris, Archaeonycteris, Hassianycteris, and Palaeochiropteryx, the resulting trees suggest that laryngeal echolocation evolved in the common ancestor of fossil and extant bats and was subsequently lost in megabats. Molecular dating suggests that crown-group bats last shared a common ancestor 52 to 54 million years ago.

El tratado de Teodomiro en su contexto histórico y paleográfico

Tras una revisión de nuestros conocimientos sobre la escritura en árabe en el año de la firma del tratado de Teodomiro, llegamos a la conclusión que estaba en desarrollo este proceso de escritura y que aún no se escribían los puntos diacríticos en las consonantes. Al hilo de ello, el objetivo principal ha sido hacer una relectura de los dos manuscritos principales representativos de las líneas de transmisión del tratado: el de al-‘Uḏrī y el de al-Ḍabbī. Finalmente, se propone un stemma de transmisión de sus textos.

Análisis de las dos líneas de transmisión del tratado de Tudmīr (94 H./713 e.C.)

Los dos textos principales de las líneas de transmisión del tratado de Tudmīr (94 H/713 e.C.), incluidos por al-‘Uḏrī y al-Ḍabbī en sus respectivas obras, son editados y traducidos en base a la relectura de los manuscritos que los contienen y de ello se extraen una serie de conclusiones sobre su proceso de copia. Luego son comparados los dos textos entre sí y se enumeran una serie de diferencias textuales. Finalmente, como hipótesis interpretativa se propone que el texto de al-‘Uḏrī es el más antiguo, y habría sido copiado de un traslado del original por su autor, mientras que la transmisión de al-Ḍabbī habría sido más reciente y se habría fundado en otra fuente más antigua que habría puesto por escrito un relato oral del texto.

Professor Sewall's lectures on the Hebrew and Oriental languages, Vol. 3d, 1768-1780

This volume contains lectures delivered by Sewall to Harvard students. The volume begins with a continuation of Lecture XIV from Volume 2. The first complete lecture in the volume, Lecture XXXIV, was delivered August 29, 1768; May 18, 1772; September 23, 1776; and June 19 1780. The last lecture in the volume, Lecture LV was delivered February 11, 1771, November 7, 1774, and May 31, 1779.

Man the measure, a new approach to history

"First printing."

Kyŏngyŏn kangŭi /

Photographic reproduction of the Kyujanggak pon in the Seoul National University Library.

End games: Euthanasia under interminable scrutiny

It is increasingly asserted that the disagreements of abstract principle between adversaries in the euthanasia debate fail to account for the complex, particular and ambiguous experiences of people at the end of their lives. A greater research effort into experiences, meaning, connection, vulnerability and motivation is advocated, during which the euthanasia 'question' should remain open. I argue that this is a normative strategy, which is felicitous to the status quo and further medicalises the end of life, but which masquerades as a value-neutral assertion about needing more knowledge.

AMBIGUIDADE COMO INVENTIVIDADE: UM ESTUDO SOBRE O SINCRETISMO RELIGIOSO NA FRONTEIRA ENTRE A ANTROPOLOGIA E A TEOLOGIA

Essa tese é um estudo sobre o problema do sincretismo religioso, quando pensado no diálogo entre a antropologia e a teologia. Para tanto, a pesquisa faz um exercício hermenêutico de ressignificação do conceito, a partir das diversas teorias sobre o sincretismo e seus usos antropológicos e teológicos, buscando subsídios no pensamento de Michel de Certeau e Paul Tillich para tal ressignificação. Assim, a perspectiva certeauniana de uma reflexão heterológica da cultura e a noção de demônico na teologia e filosofia do sentido de Tillich fundamentam a percepção do sincretismo como uma teoria da mediação entre religião e cultura. Isso significa que o sincretismo opera uma relação dialética com o seu pólo denominado, nessa tese, de diacretismo , tornando a dinâmica cultural e religiosa um espaço inventivo, posto que manifesta aspectos ambíguos de criações de sentido positivas (experiência de aproximação sincrética) e criações de sentido distorcidas (experiência de fragmentação diacrética ), essência da relação com o sagrado, vivida culturalmente. A cultura, entendida como espaço para a vivência do religioso, exprime-se em uma profunda relação entre táticas e estratégias, denotando a ambigüidade anteriormente afirmada, quando reconhece que os atores sociais em interação, mesmo que marcados por lugares próprios estrategicamente estabelecidos, enquanto lugares de poder, não inibem a formação de ações táticas que subervertem inventivamente esses mesmos lugares, dando a devida dinâmica cultural. A tese analisa, também, como estudo de caso, as implicações dessa compreensão de sincretismo para a interpretação da experiência religiosa de grupos de indígenas Guarani e Kaiowá, na Terra Indígena de Dourados /MS, na fronteira entre tradição e tradução operada pelos indígenas, a partir do Projeto da Igreja Indígena Presbiteriana (IIP), ressignificando sua alteridade religiosa na interface com os múltiplos cristianismos presentes nas aldeias, afirmando a possibilidade de um teko retã ( jeito de ser plural, múltiplo ) religioso, a partir das relações sincréticas e diacréticas propostas.

A Doutrina da Criação na teologia de Calvino e Barth: A semelhança do método como fundamento da releitura teológica barthiana.

João Calvino é o primeiro nome que nos vem à mente ao falarmos da Reforma Protestante do século XVI. A sua influência em Genebra e especialmente a sua mais famosa e importante obra teológica intitulada Institutas, que também serviu e ainda serve de manual doutrinário para os calvinistas, atestam de fato o significado de Calvino para o rotestantismo. Nas Institutas Calvino reinterpretou todos os dogmas teológicos da igreja cristã. O dogma da criação assume lugar de destaque em sua obra pois é a partir dele que Calvino abordará outros dois, também fundamentais, que são revelação e salvação em Cristo. A característica principal que encontramos no dogma da criação de Calvino é a majestade soberana de Deus. Aliás, essa característica soberania de Deus marcou fortemente o protestantismo e ainda se faz presente na tradição reformada. Se João Calvino é o primeiro nome da Reforma Protestante, talvez, sem exagero, Karl Barth seja o primeiro nome de toda a tradição reformada. Semelhante a Calvino, Barth também reinterpretou todos os dogmas da igreja cristã. Das suas muitíssimas obras destaca-se a Die Kirchliche Dogmatik contendo mais de 9.000 páginas, que também serviu e ainda serve significativamente de referência dogmática para o protestantismo. A característica principal que encontramos no dogma da criação em Barth é o pacto da graça de Deus. A minha pesquisa focalizou o dogma da criação reinterpretado por Calvino e Barth. Ao meu ver, Barth se aproxima teologicamente de Calvino, primeiro, por ser calvinista declarado e segundo, porque sua última fase teológica é exclusivamente marcada pelo dogmatismo. Nessa pesquisa procurei desenvolver os pontos de contato entre Barth e Calvino, por exemplo, a semelhança do método teológico, que também será o fundamento da minha proposta de que Barth faz de seu dogma da criação uma releitura do dogma da criação de Calvino.(AU)

O DEUS ROSIANO: ANÁLISE TEOLÓGICO-LITERÁRIA DAS IMAGENS AMBÍ-GUAS DE DEUS EM GRANDE SERTÃO: VEREDAS

Tudo é e não é . Analisar algumas imagens ambíguas de Deus em Grande Sertão: Veredas foi o objetivo desta dissertação. Para tanto, essa análise é uma tentativa interdisciplinar de leitura e interpretação, em que Teologia e Literatura são interlocutoras. A partir do romance rosiano, sob à luz hermenêutica da crítica literária e da reflexão teológica, tentamos indicar que a escritura de João Guimarães Rosa apresenta Deus de modo ambíguo. Essa assertiva é possível, pois se percebeu na provisoriedade humana, poetizada pelo escritor e personificada por Riobaldo, o traço sine qua non do modo de ver mundos misturados . Ao rememorar e renarrar as estórias sua vida, Riobaldo abre espaço ao Mistério. Nonada . Em cada travessia, o protagonista-narrador reflete acerca de Deus , por meio da fala poética cujas imagens diversas sugerem um Deus muito contrariado . Sem enquadramentos teológicos e/ou filosóficos definitivos, Rosa provoca-nos ao mostrar-nos que o Deus que roda tudo revela-se e evade-se no sertão-universo. Lugar físico-mítico. É no sertão que intentamos seguir os rastros de Deus segundo a íris riobaldiana. Olhar de constante movimento entre o obscuro e o revelado, entre o é e não é.(AU)

Inquiring how a lecturer keeps learning about their teaching:a personal case history on reflective imagination

In order to reverse the use of lecture-based teaching, it is argued that personal reflection can be used as part of the quality assurance process. This paper proposes one response to personal reflection - reflective imagination, which is summarised as an action plan with six activities. It combines two conceptual issues raised in the US, the need to think creatively about learning and the reflective mindset, and one issue raised in the UK, cultivating the entrepreneurial imagination. Reflective imagination is linked to wider social science research, the place of self and reflexivity in scholarship. Finally, a personal history case study is presented which records a visit to Harvard Business School. The visit implements the six activities associated with reflective imagination. This is a method paper exploring reflective imagination.

The UK productivity gap in the service sector: do management practices matter?

Purpose – This paper aims to contribute to the debate on the drivers of the productivity gap that exists between the UK and its major international competitors. Design/methodology/approach – From the macro perspective the paper explores the quantitative evidence on the productivity differentials and how they are measured. From the micro perspective, the article explores the quantitative evidence on the role of management practices claimed to be a key determinant in promoting firm competitiveness and in bridging the UK gap. Findings – This study suggests that management practices are an ambiguous driver of firm productivity and higher firm performance. On the methodological side, qualitative and subjective measures of either management practices or firm performance are often used. This makes the results not comparable across studies, across firms or even within firms over time. Productivity and profitability are often and erroneously interchangeably used while productivity is only one element of firm performance. On the other hand, management practices are multi-dimensional constructs that generally do not demonstrate a straightforward relationship with productivity variables. To assume that they are the only driver of higher productivity may be misleading. Moreover, there is evidence of an inverse causal relationship between management practices and firm performance. This calls into question most empirical results of the extant literature based on the unidirectional assumption of direct causality between management practices and firm performance. Research limitations/implications – These and other issues suggest that more research is needed to deepen the understanding of the UK productivity gap and more quantitative evidence should be provided on the way in which management practices contribute to the UK competitiveness. Their impact is not easily measurable due to their complexity and their complementary nature and this is a fertile ground for further research. Originality/value – This paper brings together the evidence on the UK productivity gap and its main drivers, provided by the economics, management and performance measurement literature. This issue scores very highly in the agenda of policy makers and academics and has important implications for practitioners interested in evaluating the impact of managerial best practices.

Institutional reforms, productivity and profitability:from rents to competition?

This paper explores the divergent effects of institutional reforms on firm's productivity and profits. To assess this empirically, we investigate the impact of various components of economic liberalisation on the performance of firms from Central and Eastern European countries from 1998 to 2006. The impact of reforms on profitability vis-à-vis productivity differs, which we interpret as an indication that profitability is an ambiguous measure of performance: one needs to distinguish between unproductive rents and productivity-based quasi-rents. We find that competition-enhancing liberalisation measures have more impact on state owned firms as compared with domestic and foreign owned firms. © 2012 Association for Comparative Economic Studies.

Avaliação da atenção humanizada ao abortamento em maternidade-escola, em Natal, Rio Grande do Norte

Unplanned pregnancy is experienced by millions of women worldwide. Such fact increases the risk of abortion-related morbimortality, which represents a serious public health problem. This study aims to evaluate the advances and challenges of the implementation of Humanized Abortion Care at the Maternity-School in Natal, state of Rio Grande do Norte. The research was evaluative, was preceded by an Evaluative Study, and resulted in a Case Study. The intentional sample totaled 102 subjects (60 users, 39 professionals and 3 managers). The collection techniques included documental analysis, semi-structured interview and observation with a field diary. The documental analysis was descriptive, while the Content Analysis by Bardin was used for semi-structured interviews and field diary. The Evaluative Study observed that Humanized Abortion Care is an evaluative program with preparation and pact of the logical model, of the matrix of indicators and evaluative questions. The Case Study showed that users were satisfied with the problem-solving capacity and access to the service; however, is also showed that they pointed out inadequacy in terms of environment, qualified hearing and reproductive planning. Professionals reported that the inefficiency of service consists of infrastructure and environment, which are considered inefficient and inadequate to humanized care, especially regarding patient accommodation, the lack of hospital beds, the reduced number of rooms in the surgical center and the lack of laboratory inside the maternity. Moreover, reproductive planning does not consist of an institutionalized practice in the service, and integrality with other services or partnership with the community is not in place. The Maternity Board emphasizes that the excessive demand of patients is one of the reasons that hinders the appropriate implementation of the technical standard. We then conclude that although satisfied regarding problem-solving capacity in terms of service and ease of access, there is room for improvement in qualified hearing systems, in the creation of a system to promote team work, implementation of ombudsman and satisfaction surveys. The right of shared choice did not prevail among users and health professionals with regard to the option of uterine evacuation procedure. Environment was the most mentioned category as that requiring more changes, seeing as a limited factor for the development of humanized and welcoming practices. Health professionals do not establish a periodic routine of planning practices, and such practices are not aligned with the Technical Standard. Incorporation of guidelines and availability of a plurality of methods and possibilities of choices for family planning are required. There is no institutionalization of reference and counter-reference, or partnerships with the community, which makes integrality of care not viable. The Standard needs to be included in the action plans of managers as one of the priorities in the construction of care strategies for women's health, in order to enable, allied to other initiatives, the real integration among safe conduct service, primary care network and social organizations. As a result, respect for human rights and adequate humanized care, as a way of attention and prevention of abortion, can be secured.