Data mining traditional Chinese medicine (TCM) lessons learnt from mining in law and allopathic medicine

Key decisions at the collection, pre-processing, transformation, mining and interpretation phase of any knowledge discovery from database (KDD) process depend heavily on assumptions and theorectical perspectives relating to the type of task to be performed and characteristics of data sourced. In this article, we compare and contrast theoretical perspectives and assumptions taken in data mining exercises in the legal domain with those adopted in data mining in TCM and allopathic medicine. The juxtaposition results in insights for the application of KDD for Traditional Chinese Medicine.

Performance analysis of TCM with generalized selection combining on Rayleigh fading channels

We derive the computational cutoff rate, R-o, for coherent trellis-coded modulation (TCM) schemes on independent indentically distributed (i.i.d.) Rayleigh fading channels with (K, L) generalized selection combining (GSC) diversity, which combines the K paths with the largest instantaneous signal-to-noise ratios (SNRs) among the L available diversity paths. The cutoff rate is shown to be a simple function of the moment generating function (MGF) of the SNR at the output of the (K, L) GSC receiver. We also derive the union bound on the bit error probability of TCM schemes with (K, L) GSC in the form of a simple, finite integral. The effectiveness of this bound is verified through simulations.

Terapia dietética com triglicerídeos de cadeia média(TCM) como coadjuvante do tratamento fisioterapêutico em mulheres portadoras de linfedema de membro superior

Pós-graduação em Alimentos e Nutrição - FCFAR

Maturação in vitro de ovócitos equinos : comparação entre os meios TCM 199, SOFaa e HTF:BME, e avaliação de FSH bovino, FSH equino e do hormônio de crescimento equino por meio da transferência de ovócitos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A substituição do meio TCM pelo meio BARC, suplementado com SFB, BSA ou PVA, para maturação de oócitos bovinos in vitro, não incrementa a subsequente produção de blastocistos

This study was carried out to assess the influence of bovine embryo culture medium Beltsville Agriculture Research Center (BARC), supplemented with FCS, BSA or PVA, on the in vitro oocyte maturation, evidenced by cleavage rate and blastocysts production at different developmental stages. Three experiments were performed, as follows: exp.1: addition of FCS to BARC medium at concentrations of 0, 5 and 10%; exp. 2: addition of BSA to BARC medium at concentrations of 0, 4 and 8 mg/ml; exp. 3: addition of PVA to BARC medium at concentrations of 0, 0.5 and 1.0 mg/ml. TCM 199 supplemented with bicarbonate, pyruvate, gentamicin sulfate, FSH, LH and FCS was used as control group. Oocytes obtained from cow ovaries at slaughterhouse were selected in PBS, and then matured in BARC medium supplemented with FSH, LH and gentamicin sulfate, according to the experimental design. Percoll gradient was used for sperm selection and TALP medium for IVF. In vitro embryo culture was in SOF-m medium; a humidified atmosphere with 5% CO2, in air, at 38.7oC was used for all steps. The number of oocytes reaching blastocyst, expanded blastocyst, and hatched blastocyt stages was recorded, respectively at 72 and 168 h post-insemination. ANOVA and Bonferroni t test were used to determine differences among groups. Differences of P<0.05 were taken as significant. Higher percentage (P<0.05) of cleaved oocytes was observed in group TCM + FCS than for the other groups matured in BARC supplemented with FCS or BSA, regardless the concentration used. However, the cleavage rate was similar between groups BARC plus PVA with 1 mg/ml (85.7%) and TCM + FCS (90.8%). Significant difference was found among groups for the production of blastocysts, with the control group yielding a higher number of blastocysts (results ranging from 47.4 to 51.4%, in comparison with groups using BARC + FCS (4.1 to 19.7%), BSA (1.4 to 5.6%) and PVA (5.7 to 10.6%). In conclusion, BARC medium supplemented with different macromolecules did not promote a beneficial effect on in vitro oocyte maturation, resulting in lower rate of cleavage and blastocyst production when compared with TCM + FCS medium.

Estudio y simulación de sistemas de comunicaciones digitales TCM

Desde que las Tecnologías de la Información y la Comunicación comenzaron a adquirir una gran importancia en la sociedad, uno de los principales objetivos ha sido conseguir que la información transmitida llegue en perfectas condiciones al receptor. Por este motivo, se hace necesario el desarrollo de nuevos sistemas de comunicación digital capaces de ofrecer una transmisión segura y fiable. Con el paso de los años, se han ido mejorando las características de los mismos, lo que significa importantes avances en la vida cotidiana. En este contexto, uno de los sistemas que más éxito ha tenido es la Modulación Reticulada con Codificación TCM, que aporta grandes ventajas en la comunicación digital, especialmente en los sistemas de banda estrecha. Este tipo de código de protección contra errores, basado en la codificación convolucional, se caracteriza por realizar la modulación y codificación en una sola función. Como consecuencia, se obtiene una mayor velocidad de transmisión de datos sin necesidad de incrementar el ancho de banda, a costa de pasar a una constelación superior. Con este Proyecto Fin de Grado se quiere analizar el comportamiento de la modulación TCM y cuáles son las ventajas que ofrece frente a otros sistemas similares. Se propone realizar cuatro simulaciones, que permitan visualizar diversas gráficas en las que se relacione la probabilidad de bit erróneo BER y la relación señal a ruido SNR. Además, con estas gráficas se puede determinar la ganancia que se obtiene con respecto a la probabilidad de bit erróneo teórica. Estos sistemas pasan de una modulación QPSK a una 8PSK o de una 8PSK a una 16QAM. Finalmente, se desarrolla un entorno gráfico de Matlab con el fin de proporcionar un sencillo manejo al usuario y una mayor interactividad. ABSTRACT. Since Information and Communication Technologies began to gain importance on society, one of the main objectives has been to achieve the transmitted information reaches the receiver perfectly. For this reason, it is necessary to develop new digital communication systems with the ability to offer a secure and reliable transmission. The systems characteristics have improved over the past years, what it means important progress in everyday life. In this context, one of the most successful systems is Trellis Coded Modulation TCM, that brings great advantages in terms of digital communications, especially narrowband systems. This kind of error correcting code, based on convolutional coding, is characterized by codifying and modulating at the same time. As a result, a higher data transmission speed is achieved without increasing bandwidth at the expense of using a superior modulation. The aim of this project is to analyze the TCM performance and the advantages it offers in comparison with other similar systems. Four simulations are proposed, that allows to display several graphics that show how the Bit Error Ratio BER and Signal Noise Ratio SNR are related. Furthermore, it is possible to calculate the coding gain. Finally, a Matlab graphic environment is designed in order to guarantee the interactivity with the final user.

TCM analyst 1.0 and user's guide.

Texas Department of Transportation, Austin

Fingerprinting of complex mixtures with the use of high performance liquid chromatography, inductively coupled plasma atomic emission spectroscopy and chemometrics

The molecular and metal profile fingerprints were obtained from a complex substance, Atractylis chinensis DC—a traditional Chinese medicine (TCM), with the use of the high performance liquid chromatography (HPLC) and inductively coupled plasma atomic emission spectroscopy (ICP-AES) techniques. This substance was used in this work as an example of a complex biological material, which has found application as a TCM. Such TCM samples are traditionally processed by the Bran, Cut, Fried and Swill methods, and were collected from five provinces in China. The data matrices obtained from the two types of analysis produced two principal component biplots, which showed that the HPLC fingerprint data were discriminated on the basis of the methods for processing the raw TCM, while the metal analysis grouped according to the geographical origin. When the two data matrices were combined into a one two-way matrix, the resulting biplot showed a clear separation on the basis of the HPLC fingerprints. Importantly, within each different grouping the objects separated according to their geographical origin, and they ranked approximately in the same order in each group. This result suggested that by using such an approach, it is possible to derive improved characterisation of the complex TCM materials on the basis of the two kinds of analytical data. In addition, two supervised pattern recognition methods, K-nearest neighbors (KNNs) method, and linear discriminant analysis (LDA), were successfully applied to the individual data matrices—thus, supporting the PCA approach.