Reabilitação do edifício localizado na rua Miguel Bombarda nº 69 em Loulé

Trabalho Final de Mestrado para a obtenção do grau de Mestre em Engenharia Civil na Área de Especialização de Edificações

A contribuição de técnicas modernas de reabilitação estrutural para autenticidade e integridade de edificações patrimoniais

This work discusses the study of the application of structural reinforcement and rehabilitation using modern techniques for interventions in repair works of historical buildings as well as the verification of the behavior of works that have already undergone different structural intervention techniques, with the objective of obtaining data to allow a comparative analysis of the advantages/disadvantages of techniques adapted in each case, regarding the interferences related the authenticity and integrity of the buildings belong to the constructed patrimony so as to obtain a basis for the theoretical foundation for choosing the best solution to be adopted in the case study which consists in an intervention of structural rehabilitation of the old historic building in the primary school "Augusto Severo"

Aplicação da geologia de engenharia na redução de risco geológico urbano em Itapecerica da Serra - SP: estudo de caso

O município de Itapecerica da Serra, Região Metropolitana de São Paulo (RMSP), possui uma população de 162 mil habitantes e cerca de 150 km² de área. As características geológicas e geomorfológicas do seu território e o fato de localizar-se quase inteiramente em área de proteção aos mananciais que abastecem a RMSP implicam restrições ao uso do solo e à expansão da ocupação nos moldes em que vem ocorrendo. O diagnóstico das áreas de risco geológico do município foi uma das atividades implementadas para a execução do Plano Municipal de Redução de Riscos (PMRR) do município. O PMRR tem por objetivo apresentar os resultados da identificação e da análise das situações de risco geológico-geotécnico, criando propostas de intervenções estruturais para a sua eliminação e/ou redução, estimativas de custo e estratégias para a gestão de risco no município. O mapeamento do risco geológico foi realizado em 35 áreas, onde foram identificados 66 setores de risco englobando, 419 moradias, sendo 175 moradias em setores cujo grau de risco foi classificado como alto ou muito alto. As propostas de intervenção estrutural buscaram a aderência entre o processo geodinâmico atuante e a tipologia de intervenção sugerida para estabilização e controle. A definição de critérios para a hierarquização das intervenções propostas contribuiu para a inserção das propostas do PMRR no planejamento plurianual do município de Itapecerica da Serra.

Impacto gerado na vida das mulheres removidas das favelas

Interventions that seek to change the areas occupied by squatters have been one of the most common forms of Urban Management Policies, trying revolver one of the major problems of Brazilian metropolises, namely the precarious living conditions of a large part of the population in the city. A Pedreira Prado Lopes, a slum located in the northwestern region of Belo Horizonte, is one of twelve local benefit program by urbanization of slums Vila Viva, a program of structural intervention in Slums at the municipal level. These interventions, which are benefiting 9,000 residents have funds of R$37,4 millions the PAC (Growth Acceleration Program) and were guided by PGE - Specific Global Plan prepared by technicians URBEL (Urbanization Company of Belo Horizonte) in 1998. This project intervention was the creation of a set of housing for former slum housing. The objective of this research is to know how this intervention impacted the lives of residents after settling in condominiums, seeking to describe the changes on the horizon of women who are in most household heads residents of these buildings, as shown by studies of the IBGE (Brazilian Institute of Geography and Statistics), 2011

Impacto gerado na vida das mulheres removidas das favelas

Interventions that seek to change the areas occupied by squatters have been one of the most common forms of Urban Management Policies, trying revolver one of the major problems of Brazilian metropolises, namely the precarious living conditions of a large part of the population in the city. A Pedreira Prado Lopes, a slum located in the northwestern region of Belo Horizonte, is one of twelve local benefit program by urbanization of slums Vila Viva, a program of structural intervention in Slums at the municipal level. These interventions, which are benefiting 9,000 residents have funds of R$37,4 millions the PAC (Growth Acceleration Program) and were guided by PGE - Specific Global Plan prepared by technicians URBEL (Urbanization Company of Belo Horizonte) in 1998. This project intervention was the creation of a set of housing for former slum housing. The objective of this research is to know how this intervention impacted the lives of residents after settling in condominiums, seeking to describe the changes on the horizon of women who are in most household heads residents of these buildings, as shown by studies of the IBGE (Brazilian Institute of Geography and Statistics), 2011

Impacto gerado na vida das mulheres removidas das favelas

Interventions that seek to change the areas occupied by squatters have been one of the most common forms of Urban Management Policies, trying revolver one of the major problems of Brazilian metropolises, namely the precarious living conditions of a large part of the population in the city. A Pedreira Prado Lopes, a slum located in the northwestern region of Belo Horizonte, is one of twelve local benefit program by urbanization of slums Vila Viva, a program of structural intervention in Slums at the municipal level. These interventions, which are benefiting 9,000 residents have funds of R$37,4 millions the PAC (Growth Acceleration Program) and were guided by PGE - Specific Global Plan prepared by technicians URBEL (Urbanization Company of Belo Horizonte) in 1998. This project intervention was the creation of a set of housing for former slum housing. The objective of this research is to know how this intervention impacted the lives of residents after settling in condominiums, seeking to describe the changes on the horizon of women who are in most household heads residents of these buildings, as shown by studies of the IBGE (Brazilian Institute of Geography and Statistics), 2011

A contribuição de técnicas modernas de reabilitação estrutural para autenticidade e integridade de edificações patrimoniais

This work discusses the study of the application of structural reinforcement and rehabilitation using modern techniques for interventions in repair works of historical buildings as well as the verification of the behavior of works that have already undergone different structural intervention techniques, with the objective of obtaining data to allow a comparative analysis of the advantages/disadvantages of techniques adapted in each case, regarding the interferences related the authenticity and integrity of the buildings belong to the constructed patrimony so as to obtain a basis for the theoretical foundation for choosing the best solution to be adopted in the case study which consists in an intervention of structural rehabilitation of the old historic building in the primary school "Augusto Severo"

Convento de S. Francisco em Montemor-o-Novo: contributos para a sua recuperação e valorização

O convento de S. Francisco, em Montemor-o-Novo, que durante cerca de quatro séculos esteve implantado fora do contexto urbano local, está, na actualidade, envolvido pela malha habitacional e por equipamentos colectivos. O estado de parcial abandono e de degradação acelerada em que se encontra o conjunto, obriga a que, por todas as formas, haja empenho da comunidade social na sua urgente recuperação e valorização cultural. É efectuada uma leitura do conjunto edificado remanescente, uma análise dos materiais aplicados e das técnicas construtivas utilizadas, a que se segue um diagnóstico do estado patológico, identificando-se as anomalias mais relevantes, de natureza estrutural e não estrutural. Apresentam-se propostas para a reparação e eliminação dos factores de alteração. Finalmente, sugerem-se algumas possibilidades para a valorização futura do conjunto, enquanto peça importante do nosso património colectivo. ABSTRACT; The St. Francisco convent in Montemor-o-Novo which during about four centuries was outside the urban context, is nowadays completely involved by the urban agglomerate and collective facilities. The situation of partial abandonment and the accelerated degradation where the joint is, requires to, by all the ways have interest by the social community in its urgent recovery and in its cultural valorization. Is done a reading of the built joint, an analyse of the employed materials and the techniques of construction used, which is followed by a diagnostic of the pathological condition, identifying the most outstanding anomalies, of structural and not structural character, presenting suggestions to its reparation and reduce of the transformation agents. Finally, are enumerate some possibilities to the future benefit of the joint, while important piece of our collective heritage.

A contribuição de técnicas modernas de reabilitação estrutural para autenticidade e integridade de edificações patrimoniais

This work discusses the study of the application of structural reinforcement and rehabilitation using modern techniques for interventions in repair works of historical buildings as well as the verification of the behavior of works that have already undergone different structural intervention techniques, with the objective of obtaining data to allow a comparative analysis of the advantages/disadvantages of techniques adapted in each case, regarding the interferences related the authenticity and integrity of the buildings belong to the constructed patrimony so as to obtain a basis for the theoretical foundation for choosing the best solution to be adopted in the case study which consists in an intervention of structural rehabilitation of the old historic building in the primary school "Augusto Severo"

Assessment by doppler ultrasound of entheseal lesions in spondyloarthritis : a longitudial study to determine structural damage and disease activity lesions

RESUMO: Enthesitis is the hallmark of spondyloarthritis (SpA), and is observed in all subtypes. Wide information on SpA abnormalities, including synovitis, tendinitis and enthesitis, can be efficiently perceived by Doppler ultrasound. Furthermore, several studies on imaging of enthesis showed that imaging techniques are better than clinical examination to detect enthesis alterations; and vascularized enthesitis detected by Doppler ultrasound appears to be a valuable diagnostic tool to confirm SpA diagnosis. However, data published until now concerning entheseal elementary alterations that characterize SpA enthesitis (enthesis inflammatory activity) or enthesopathy (permanent structural changes) reflect rather the authors’ empiric opinion than a methodological validation process. In this sense it seems crucial to identify elementary entheseal lesions associated with activity or damage, in order to improve monitoring and treatment response in SpA patients. The development of better assessment tools is today a challenge and a need in SpA. The first study of this thesis focused on the analysis of the reliability of inter-lector and inter-ultrasonography equipment of Madrid sonography enthesitis index (MASEI). Fundamental data for the remaining unrolling project validity. In the second and third studies we concerned about two entheseal elemental lesions: erosions and bursa. In literature erosions represent a permanent structural damage, being useful for monitoring joint injury, disease activity and therapeutic response in many rheumatic diseases; and to date, this concept has been mostly applied in rheumatoid arthritis (RA). Unquestionably, erosion is a tissue-related damage and a structural change. However, the hypothesis that we decided to test was if erosions represent a permanent structural change that can only grow and worsen over time, as occurs in RA, or a transitory alteration. A longitudinal study of early SpA patients was undertaken, and the Achilles enthesis was used as a model. Our results strongly suggested that previously detected erosions could disappear during the course of the disease, being consistent with the dynamic behavior of erosion over time. Based on these striking results it seems reasonable to suggest that the new-bone formation process in SpA could be associated with the resolution of cortical entheseal erosion over time. These results could also be in agreement with the apparent failure of anti-tumor necrosis factor (TNF) therapies to control bone proliferation in SpA; and with the relation of TNF-α, Dickkopf-related protein 1 (Dkk-1) and the regulatory molecule of the Wnt signaling pathway in the bone proliferation in SpA. In the same model, we then proceeded to study the enthesis bursa. Interestingly, the Outcome Measures in Rheumatology Clinical Trials (OMERACT) enthesopathy definition does not include bursa as an elementary entheseal lesion. Nonetheless, bursa was included in 46% of the enthesis studies in a recently systematic literature review, being in agreement with the concept of “synovio-entheseal complex” that includes the link between enthesitis and osteitis in SpA. It has been clarified in recent data that there is not only a close functional integration of the enthesis with the neighboring bone, but also a connection between enthesitis and synovitis. Therefore, we tried to assess the prevalence and relevance of the bursa-synovial lesion in SpA. Our findings showed a significant increase of Achilles bursa presence and thickness in SpA patients compared to controls (healthy/mechanical controls and RA controls). These results raise awareness to the need to improve the enthesopathy ultrasonographic definition. In the final work of this thesis, we have explored new perspectives, not previously reported, about construct validity of enthesis ultrasound as a possible activity outcome in SpA. We performed a longitudinal Achilles enthesis ultrasound study in patients with early SpA. Achilles ultrasound examinations were performed at baseline, six- and twelve-month time periods and compared with clinical outcome measures collected at basal visit. Our results showed that basal erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are higher in patients with Doppler signal in enthesis, and even that higher basal ESR, CRP and Ankylosing Spondylitis Disease Activity Score (ASDAS) predicted a higher Doppler signal (an ultrasound alteration accepted as representative of inflammation) six months later. Patients with very high disease activity assessed by ASDAS (>3.5) at baseline had significantly higher Achilles total ultrasound score verified at the same time; and ASDAS <1.3 predicted no Doppler signal at six and twelve months. This seems to represent a connection between classical biomarkers and clinical outcomes associated with SpA activity and Doppler signal, not only at the same time, but also for the following months. Remarkably, patients with inactive disease (ASDAS < 1.3) at baseline had no Doppler signal at six and twelve months. These findings reinforce the potential use of ultrasound related techniques for disease progression assessment and prognosis purposes. Intriguingly, Ankylosing Spondylitis Disease Activity Index (BASDAI) didn’t show significant differences between different cut-offs concerning ultrasound lesions or Doppler signal, while verified with ASDAS. These results seem to indicate that ASDAS reflects better than BASDAI what happens in the enthesis. The work herein discussed clearly shows the potential utility of ultrasound in enthesis assessment in SpA patients, and can be important for the development of ultrasound activity and structural damage scores for diagnosis and monitoring purposes. Therefore, local promotion of this technique constitutes a medical intervention that is worth being tested in SpA patients for diagnosis, monitoring and prognosis purposes.

Neurocognitive profile and cognitive intervention in Alzheimer's disease

Tese de Doutoramento em Psicologia (Especialidade de Psicologia Clínica)

Intermediary and structural determinants of early childhood health in Colombia: exploring the role of communities

This study examines how structural determinants influence intermediary factors of child health inequities and how they operate through the communities where children live. In particular, we explore individual, family and community level characteristics associated with a composite indicator that quantitatively measures intermediary determinants of early childhood health in Colombia. We use data from the 2010 Colombian Demographic and Health Survey (DHS). Adopting the conceptual framework of the Commission on Social Determinants of Health (CSDH), three dimensions related to child health are represented in the index: behavioural factors, psychosocial factors and health system. In order to generate the weight of the variables and take into account the discrete nature of the data, principal component analysis (PCA) using polychoric correlations are employed in the index construction. Weighted multilevel models are used to examine community effects. The results show that the effect of household’s SES is attenuated when community characteristics are included, indicating the importance that the level of community development may have in mediating individual and family characteristics. The findings indicate that there is a significant variance in intermediary determinants of child health between-community, especially for those determinants linked to the health system, even after controlling for individual, family and community characteristics. These results likely reflect that whilst the community context can exert a greater influence on intermediary factors linked directly to health, in the case of psychosocial factors and the parent’s behaviours, the family context can be more important. This underlines the importance of distinguishing between community and family intervention programmes.