Escribir en pasado. La invención de las fechas en las reediciones y reescrituras de Ricardo Piglia

En 2005, Ricardo Piglia publica en la editorial Anagrama, que ya venía reeditando casi toda su obra, el primer libro que antes de ser enviado a la imprenta por Jorge Herralde no existía : El último lector. La edición de éste, tanto como la de La invasión de 2006 revelan el empeño del escritor en la construcción de un atraso del tiempo literario que consiste en volverse y volver sus libros siempre un poco más remotos. Piglia construye su obra como si estuviera formada siempre por textos del pasado o fijados en el pasado y consolida desde allí su anacronismo como un bien

Escritores de marca : Voces argentinas en el catálogo de Anagrama

El interés de la industria editorial española por la literatura hispanoamericana resurge a partir de los años noventa del siglo XX, al tiempo que se fomentan otras relaciones culturales y económicas de diverso tipo. Por un lado, los grandes grupos apuestan con riesgos mínimos y controlados; por otro, editoriales independientes tienen por objetivo descubrir nuevas voces con talento y calidad literaria. En el caso de Anagrama se ha abierto el catálogo a escritores como Bolaño, Aira, Pitol, Neuman o Pauls, pero también se ha creado una especie de redil anagramático, en palabras de Herralde, y así un grupo de escritores "de marca" disfruta del capital simbólico de la editorial, al tiempo que lo incrementa con el suyo propio gracias a su notable producción y su proyección internacional

Escribir en pasado. La invención de las fechas en las reediciones y reescrituras de Ricardo Piglia

En 2005, Ricardo Piglia publica en la editorial Anagrama, que ya venía reeditando casi toda su obra, el primer libro que antes de ser enviado a la imprenta por Jorge Herralde no existía : El último lector. La edición de éste, tanto como la de La invasión de 2006 revelan el empeño del escritor en la construcción de un atraso del tiempo literario que consiste en volverse y volver sus libros siempre un poco más remotos. Piglia construye su obra como si estuviera formada siempre por textos del pasado o fijados en el pasado y consolida desde allí su anacronismo como un bien

Escritores de marca : Voces argentinas en el catálogo de Anagrama

El interés de la industria editorial española por la literatura hispanoamericana resurge a partir de los años noventa del siglo XX, al tiempo que se fomentan otras relaciones culturales y económicas de diverso tipo. Por un lado, los grandes grupos apuestan con riesgos mínimos y controlados; por otro, editoriales independientes tienen por objetivo descubrir nuevas voces con talento y calidad literaria. En el caso de Anagrama se ha abierto el catálogo a escritores como Bolaño, Aira, Pitol, Neuman o Pauls, pero también se ha creado una especie de redil anagramático, en palabras de Herralde, y así un grupo de escritores "de marca" disfruta del capital simbólico de la editorial, al tiempo que lo incrementa con el suyo propio gracias a su notable producción y su proyección internacional

Escribir en pasado. La invención de las fechas en las reediciones y reescrituras de Ricardo Piglia

En 2005, Ricardo Piglia publica en la editorial Anagrama, que ya venía reeditando casi toda su obra, el primer libro que antes de ser enviado a la imprenta por Jorge Herralde no existía : El último lector. La edición de éste, tanto como la de La invasión de 2006 revelan el empeño del escritor en la construcción de un atraso del tiempo literario que consiste en volverse y volver sus libros siempre un poco más remotos. Piglia construye su obra como si estuviera formada siempre por textos del pasado o fijados en el pasado y consolida desde allí su anacronismo como un bien

Escritores de marca : Voces argentinas en el catálogo de Anagrama

El interés de la industria editorial española por la literatura hispanoamericana resurge a partir de los años noventa del siglo XX, al tiempo que se fomentan otras relaciones culturales y económicas de diverso tipo. Por un lado, los grandes grupos apuestan con riesgos mínimos y controlados; por otro, editoriales independientes tienen por objetivo descubrir nuevas voces con talento y calidad literaria. En el caso de Anagrama se ha abierto el catálogo a escritores como Bolaño, Aira, Pitol, Neuman o Pauls, pero también se ha creado una especie de redil anagramático, en palabras de Herralde, y así un grupo de escritores "de marca" disfruta del capital simbólico de la editorial, al tiempo que lo incrementa con el suyo propio gracias a su notable producción y su proyección internacional

Macrophage and TGF-beta immunohistochemical expression in Jorge Lobo`s disease

Jorge Lobo`s disease, or lacaziosis, is a chronic deep mycosis that clinically manifests as solid, variable-sized nodular parakeloidal lesions. Few studies have characterized the in situ cellular and humoral immune response, especially the involvement of cytokines with immunosuppressive effects such as TGF-beta. The objective this paper was to analyze the expression of TGF-beta in cutaneous lesions in lacaziosis and investigate its importance in the etiopathogy of the disease. The results indicate that the abundance of collagen bands, together with weak immunolabeling for CD68 seen in macrophages, indicates a concomitant effect of TGF-beta inhibiting macrophages and inducing fibrosis, which is responsible for the keloid aspect frequently acquired by these lesions. Finally, the evolution of the infection supports the hypothesis that TGF-beta plays a fundamental role in the etiopathology of Lacazia loboi infection, either by inhibiting the cellular immune response mainly mediated by macrophages or by inducing fibrosis. Further studies are necessary to better characterize the phenotype of the inflammatory infiltrate as well as the participation of other cytokines and growth factors in the tissue response of the host in Jorge Lobo`s disease. (C) 2008 Published by Elsevier Inc.

Immunohistochemical study of Langerhans cells in cutaneous lesions of the Jorge Lobo`s disease

Jorge Lobo`s disease is a chronic infection caused by the fungus Lacazia loboi endemic in South America. The infection is characterized by the appearance of parakeloidal, ulcerated or verrucous nodular or plaque-like cutaneous lesions. The histopathological aspect is characterized by poorly organized granulomas with histiocytes and multinucleated giant cells. Little is known about local immune response in lobomycosis skin lesions. Thirty-three skin biopsies from patients with Jorge Lobo`s disease were selected from Ambulatory of Dermatology, UFPA. The control group was constituted by ten biopsies from normal skin. Langerhans cells were identified by immunohistochemistry using anti-CD1a antibody (Serotec). The number of positive cells was statistically analyzed. Langerhans cells were visualized along the epidermis in biopsies from Jorge Lobo`s disease and the morphology and the number of Langerhans cells did not differ from normal skin (p > 0.05). In Jorge Lobo`s disease, this cell population probably presents some escape mechanism of the local immune system to evade the antigen presentation by those cells. (C) 2010 Published by Elsevier B.V.

Detection of cytokines and nitric oxide synthase in skin lesions of Jorge Lobo`s disease patients

Studies investigating the immunopathological aspects of Jorge Lobo`s disease have shown that the inflammatory infiltrate consists mainly of histiocytes and multinucleated giant cells involving numerous yeast-like cells of Lacazia loboi, with the T lymphocytes more common than B lymphocytes and plasma cells. The quantification of cytokines in peripheral blood mononuclear cells culture supernatant has revealed alterations in the cytokines profile, characterized by predominance of a Th2 profile. In view of these findings and of the role of cytokines in cell interactions, the objective of the present study was to investigate the presence of the cytokines IL-10, TGF-ss 1 and TNF-alpha, as well as iNOS enzyme in granulomas induced by L. loboi. Histological sections obtained from skin lesions of 16 patients were analyzed by immunohistochemistry for the presence of these cytokines and iNOS. The results showed that TGF-ss 1 was the cytokine most frequently expressed by cells present in the inflammatory infiltrate, followed by IL-10. There was a minimum to discrete positivity of cells expressing TNF-alpha and iNOS. The results suggest that the presence of immunosuppressive cytokines in skin lesions of patients with the mycosis might be responsible for the lack of containment of the pathogen as demonstrated by the presence of numerous fungi in the granuloma.

Caminhos da tradução: Cavafy, Montale e Jorge de Sena -Divagações-

Revista Lusófona de Línguas, Culturas e Tradução

Entre Nós : entrevista a José Jorge Letria

Emissões - Entre Nós

Jorge Silva Melo: "Filmar tem de ser tão simples como estar ali naturalmente"

O projecto “Principais tendências no cinema português contemporâneo” nasceu no Departamento de Cinema da ESTC, com o objectivo de desenvolver investigação especializada a partir de um núcleo formado por alunos da Licenciatura em Cinema e do Mestrado em Desenvolvimento de Projecto Cinematográfico, a que se juntaram professores-investigadores membros do CIAC e convidados. O que agora se divulga corresponde a dois anos e meio de trabalho desenvolvido pela equipa de investigação, entre Abril de 2009 e Novembro de 2011. Dada a forma que ele foi adquirindo, preferimos renomeá-lo, para efeitos de divulgação, “Novas & velhas tendências no cinema português contemporâneo”.

Jorge Cramez: "Imagino-me a agradecer um Óscar"

O projecto “Principais tendências no cinema português contemporâneo” nasceu no Departamento de Cinema da ESTC, com o objectivo de desenvolver investigação especializada a partir de um núcleo formado por alunos da Licenciatura em Cinema e do Mestrado em Desenvolvimento de Projecto Cinematográfico, a que se juntaram professores-investigadores membros do CIAC e convidados. O que agora se divulga corresponde a dois anos e meio de trabalho desenvolvido pela equipa de investigação, entre Abril de 2009 e Novembro de 2011. Dada a forma que ele foi adquirindo, preferimos renomeá-lo, para efeitos de divulgação, “Novas & velhas tendências no cinema português contemporâneo”.

Multi-stage evolution of a sub-aerial volcanic ridge over the last 1.3 Myr: S. Jorge Island, Azores Triple Junction

New K/Ar dating and geochemical analyses have been carried out on the WNW-ESE elongated oceanic island of S. Jorge to reconstruct the volcanic evolution of a linear ridge developed close to the Azores triple junction. We show that S. Jorge sub-aerial construction encompasses the last 1.3 Myr, a time interval far much longer than previously reported. The early development of the ridge involved a sub-aerial building phase exposed in the southeast end of the island and now constrained between 1.32 +/- 0.02 and 1.21 +/- 0.02 Ma. Basic lavas from this older stage are alkaline and enriched in incompatible elements, reflecting partial melting of an enriched mantle source. At least three differentiation cycles from alkaline basalts to mugearites are documented within this stage. The successive episodes of magma rising, storage and evolution suggest an intermittent reopening of the magma feeding system, possibly due to recurrent tensional or trans-tensional tectonic events. Present data show a gap in sub-aerial volcanism before a second main ongoing building phase starting at about 750 ka. Sub-aerial construction of the S. Jorge ridge migrated progressively towards the west, but involved several overlapping volcanic episodes constrained along the main WNW-ESE structural axis of the island. Malic magmas erupted during the second phase have been also generated by partial melting of an enriched mantle source. Trace element data suggest, however, variable and lower degrees of partial melting of a shallower mantle domain, which is interpreted as an increasing control of lithospheric deformation on the genesis and extraction of primitive melts during the last 750 kyr. The multi-stage development of the S. Jorge volcanic ridge over the last 1.3 Myr has most likely been greatly influenced by regional tectonics, controlled by deformation along the diffuse boundary between the Nubian and the Eurasian plates, and the increasing effect of sea-floor spreading at the Mid-Atlantic Ridge.

Palaeomagnetic study of a subaerial volcanic ridge (Sao Jorge Island, Azores) for the past 1.3 Myr: evidence for the Cobb Mountain Subchron, volcano flank instability and tectonomagmatic implications

We present a palaeomagnetic study on 38 lava flows and 20 dykes encompassing the past 1.3 Myr on S. Jorge Island (Azores ArchipelagoNorth Atlantic Ocean). The sections sampled in the southeastern and central/western parts of the island record reversed and normal polarities, respectively. They indicate a mean palaeomagnetic pole (81.3 degrees N, 160.7 degrees E, K= 33 and A95= 3.4 degrees) with a latitude shallower than that expected from Geocentric Axial Dipole assumption, suggesting an effect of non-dipolar components of the Earth magnetic field. Virtual Geomagnetic Poles of eight flows and two dykes closely follow the contemporaneous records of the Cobb Mountain Subchron (ODP/DSDP programs) and constrain the age transition from reversed to normal polarity at ca. 1.207 +/- 0.017 Ma. Volcano flank instabilities, probably related to dyke emplacement along an NNWSSE direction, led to southwestward tilting of the lava pile towards the sea. Two spatially and temporally distinct dyke systems have been recognized on the island. The eastern is dominated by NNWSSE trending dykes emplaced before the end of the Matuyama Chron, whereas in the central/western parts the eruptive fissures oriented WNWESE controlled the westward growth of the S. Jorge Island during the Brunhes Chron. Both directions are consistent with the present-day regional stress conditions deduced from plate kinematics and tectonomorphology and suggest the emplacement of dykes along pre-existing fractures. The distinct timing and location of each dyke system likely results from a slight shift of the magmatic source.