Inactivation of V79 cells by low-energy protons, deuterons and helium-3 ions

Previous work by ourselves and by others has demonstrated that protons with a linear energy transfer (LET) about 30 V mu m(-1) are more effective at killing cells than doubly charged particles of the same LET. In this work we show that by using deuterons, which have about twice the range of protons with the same LET, it is possible to extend measurements of the RBE of singly charged particles to higher LET (up to 50 keV mu m(-1)). We report the design and use of a new arrangement for irradiating V79 mammalian cells. Cell survival. measurements have been made using protons in the energy range 1.0-3.7 MeV, deuterons in the energy range 0.9-3.4 MeV and He-3(2+) ions in the energy range 3.4-6.9 MeV;. This corresponds to volume-averaged LET (within the cell nucleus) between 10 and 28 keV mu m(-1) for protons, 18-50 keV mu m(-1) for deuterons, and 59-106 keV mu m(-1) for helium ions. Our results show no difference in the effectiveness of protons and deuterons matched for LET. However, for LET above about 30 keV mu m(-1) singly charged particles are more effective at inactivating cells than doubly-charged particles of the same LET and that this difference can be understood in terms of the radial dose distribution around the primary ion track.

Spin dependence of slow neutron scattering by deuterons /

Work performed at the Argonne National Laboratory.

Attenuation and high energy neutron production measurements for 190 mev deuterons and 340 mev protons /

"Issued August 29, 1951"

Coulomb expansion of deuterated methane clusters irradiated by an ultrashort intense laser pulse

The simulations of three-dimensional particle dynamics show that when irradiated by an ultrashort intense laser pulse, the deuterated methane cluster expands and the majority of deuterons overrun the more slowly expanding carbon ions, resulting in the creation of two separated subclusters. The enhanced deuteron kinetic energy and a narrow peak around the energy maximum in the deuteron energy distribution make a considerable contribution to the efficiency of nuclear fusion compared with the case of homonuclear deuterium clusters. With the intense laser irradiation, the nuclear fusion yield increases with the increase of the cluster size, so that deuterated heteronuclear clusters with larger sizes are required to achieve a greater neutron yield.

Nuclear fusion from Coulomb explosions of deuterated methane clusters subjected to ultraintense femtosecond laser pulses

This paper reports that Coulomb explosions taken place in the experiment of heteronuclear deuterated methane clusters ((CD4)(n)) in a gas jet subjected to intense femtosecond laser pulses (170 mJ, 70 fs) have led to table-top laser driven DD nuclear fusion. The clusters produced in supersonic expansion had an average energies of deuterons produced in the laser-cluster interaction were 60 and 1.5 KeV, respectively. From DD collisons of energetic deuterons, a yield of 2.5(+/-0.4)x10(4) fusion neutrons of 2.45 MeV per shot was realized, giving rise to a neutron production efficiency of about 1.5 x 10(5) per joule of incident laser pulse energy. Theoretical calculations were performed and a fairly good agreement of the calculated neutron yield with that obtained from the present experiment was found.

The deuteron-deuteron reaction and the stopping cross section of D_2O ice below 600 kev

The energy loss of protons and deuterons in D_2O ice has been measured over the energy range, E_p 18 - 541 kev. The double focusing magnetic spectrometer was used to measure the energy of the particles after they had traversed a known thickness of the ice target. One method of measurement is used to determine relative values of the stopping cross section as a function of energy; another method measures absolute values. The results are in very good agreement with the values calculated from Bethe’s semi-empirical formula. Possible sources of error are considered and the accuracy of the measurements is estimated to be ± 4%.

The D(dp)H^3 cross section has been measured by two methods. For E_D = 200 - 500 kev the spectrometer was used to obtain the momentum spectrum of the protons and tritons. From the yield and stopping cross section the reaction cross section at 90° has been obtained.

For E_D = 35 – 550 kev the proton yield from a thick target was differentiated to obtain the cross section. Both thin and thick target methods were used to measure the yield at each of ten angles. The angular distribution is expressed in terms of a Legendre polynomial expansion. The various sources of experimental error are considered in detail, and the probable error of the cross section measurements is estimated to be ± 5%.

Two overrun phenomena and their effects on fusion yield in the Coulomb explosion of heteronuclear clusters

Two overrun effects in the Coulomb explosion dynamics of heteronuclear clusters have been investigated theoretically by the use of a simplified electrostatic model. When the charge-to-mass ratio of light ions is higher than that of heavy ions, the light ions can overtake the heavy ions inside the cluster and acquire a higher kinetic energy. Further, if the charge density of the heavy ions is twice as high as that of the light ions, i.e. a proposed competitive parameter xi = rho BqB/rho AqA > 2, the inner light ions can overtake those light ions on the surface of the cluster and form a shock shell during the explosion, which might drive the intracluster collision and fusion of the light ions. Different regimes of nuclear fusion are discussed and the corresponding neutron yields are estimated. Our analysis indicates that the probability of intracluster fusion is quite low even if deuterated heteronuclear clusters such as (DI)(n) with large size and high competitive parameter are employed. However, heteronuclear clusters are still a better candidate compared with homonuclear clusters for enhancing the total intercluster fusion yield because both a higher energy region and a higher proportion of deuterons distributing in the energy region can be created in the deuterated heteronuclear clusters.

Electromagnetic decay of the 1.7- and 2.43-MeV levels in ^9Be

The 1.7- and 2.43-MeV levels in ⁹Be were populated with the reaction ¹¹B(d, α)⁹Be* by bombarding thin boron on carbon foils with 1.7-MeV deuterons. The alpha particles were analyzed in energy with a surface-barrier counter set at the unique kinematically determined angle and the recoiling ⁹Be nuclei at 90^o were analyzed in rigidity with a magnetic spectrometer, in energy by a surface-barrier counter at the spectrometer focus, and in velocity by the time delay between an alpha and a ⁹Be count. When a pulse from the spectrometer counter was in the appropriate delayed coincidence with a pulse from the alpha counter, the two pulses were recorded in a two-dimensional pulse height analyzer. Most of the ⁹Be* decay by particle breakup. Only those that gamma decay are detected by the spectrometer counter. Thus the experiment provides a direct measurement of Γ_rad/Γ. Analysis of 384 observed events gives Γ_rad/Γ = (1.16 ± 0.14) X 10^-4 for the 2.43-MeV level. Combining this ratio with the value of Γ_rad = 0.122 ± 0.015 eV found from inelastic electron scattering gives Γ = (1.05 ± 0.18) keV. For the 1.7-MeV level, an upper limit, Γ_rad/Γ ≤ 2.4 = 10^-5, was determined.

Luminosity determination for the dd→αK+K-experiment atANKE/COSY

High resolution studies of a0/f0(980) decays into channels involving open strangeness are currently being performed at COSY-Jülich. As a “filter” for isospin-zero intermediate states, i.e. to selectively produce the f0(980) resonance, the dd→αK+K− reaction was measured with the magnetic ANKE spectrometer. In order to determine the luminosity of this experiment, the elastically and quasi-elastically scattered deuterons were recorded simultaneously with the αK+K− events. Here we report about the luminosity determination via investigating the (quasi-) elastic deuterons at ANKE.

First-principles study of ferroelectricity and isotope effects in H-bonded KH2PO4 crystals

By means of extensive first-principles calculations we studied the ferroelectric phase transition and the associated isotope effect in KH2PO4 (KDP). Our calculations revealed that the spontaneous polarization of the ferroelectric phase is due to electronic charge redistributions and ionic displacements which are a consequence of proton ordering, and not vice versa. The experimentally observed double-peaked proton distribution in the paraelectric phase cannot be explained by a dynamics of only protons. This requires, instead, collective displacements within clusters that include also the heavier ions. These tunneling clusters can explain the recent evidence of tunneling obtained from Compton scattering measurements. The sole effect of mass change upon deuteration is not sufficient to explain the huge isotope effect. Instead, we find that structural modifications deeply connected with the chemistry of the H bonds produce a feedback effect on tunneling that strongly enhances the phenomenon. The resulting influence of the geometric changes on the isotope effect agrees with experimental data from neutron scattering. Calculations under pressure allowed us to analyze the issue of universality in the disappearance of ferroelectricity upon compression. Compressing DKDP so that the distance between the two peaks in the deuteron distribution is the same as for protons in KDP, corresponds to a modification of the underlying double-well potential, which becomes 23 meV shallower. This energy difference is what is required to modify the O-O distance in such a way as to have the same distribution for protons and deuterons. At the high pressures required experimentally, the above feedback mechanism is crucial to explain the magnitude of the geometrical effect.

Bright Laser-Driven Neutron Source Based on the Relativistic Transparency of Solids

Neutrons are unique particles to probe samples in many ?elds of research ranging from biology to material sciences to engineering and security applications. Access to bright, pulsed sources is currently
limited to large accelerator facilities and there has been a growing need for compact sources over the recent years. Short pulse laser driven neutron sources could be a compact and relatively cheap way to
produce neutrons with energies in excess of 10 MeV. For more than a decade experiments have tried to obtain neutron numbers suf?cient for applications. Our recent experiments demonstrated an ion acceleration mechanism based on the concept of relativistic transparency. Using this new mechanism, we produced an intense beam of high energy (up to 170 MeV) deuterons directed into a Be converter to
produce a forward peaked neutron ?ux with a record yield, on the order of 1010 n=sr. We present results comparing the two acceleration mechanisms and the ?rst short pulse laser generated neutron radiograph.

Monitoring the positioning of short polycationic peptides in model lipid bilayers by combining hydrogen/deuterium exchange and electrospray ionization mass spectrometry

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Kohärente Elektroproduktion von neutralen Pionen am Deuteron nahe der Schwelle

Im Rahmen dieser Arbeit wurde das an derDrei-Spektrometer-Anlage derA1-Kollaboration des Institutes für Kernphysik derUniversität Mainzdurchgeführte Koinzidenz-Experiment zur Elektroproduktionvon neutralenPionen nahe der Schwelle am Deuteron bei einemViererimpulsübertrag vonq^2=-0.1 GeV^2/c^2 vorgestellt. Diese Messung stellt denerstenexperimentellen Zugang zum longitudinalen Anteil desWirkungsquerschnittes dieser Reaktion überhaupt dar. ZurSeparationder verschiedenen Wirkungsquerschnittsanteile wurden Datenbei dreiPolarisationen des virtuellen Photons bis 4 MeV oberhalb derPionproduktionsschwelle genommen. Eine besondereHerausforderung ergabsich aus der mit beta=0.16 geringsten bisher mit demDetektorsystem nachgewiesenen Teilchengeschwindigkeit derDeuteronenund dem erstmaligen kohärenten Nachweis des Deuterons. Aus den in zwei Strahlzeiten gewonnenen Daten wurden mitHilfe einerRosenbluth-Separation der longitudinale und transversaleAnteil desWirkungsquerschnittes ermittelt. Unter Verwendung aller 144Datenpunkte derdifferentiellen Wirkungsquerschnitte konnten bei schwachenAnnahmen für dieImpulsabhängigkeit der p-Wellen-Beiträge die Beträge ders-Wellen-Amplituden Ed und Ld an der Schwelle extrahiertwerden: |Ed|<0.68*10^(-3)/M_pi+ und |Ld|=(0.81+/-0.18)*10^(-3)/M_pi+ Die experimentell bestimmten Werte liegen weit unter denVorhersagen der chiralen Störungstheorie. Ausgedrückt durchdens-Wellen-Wirkungsquerschnitt a_0 entspricht der gemesseneWert nurca. 1/6 der Vorhersage. Die gemessenen Winkelverteilungenderdifferentiellen Wirkungsquerschnitte können als wichtigeGrundlage zurIntegration der bisher in den Modellen nicht enthaltenenp-Wellen-Beiträge dienen.