Catálogo das coleções entomológicas da Faculdade de Saúde Pública da Universidade de São Paulo - (2ª Série II): Culicidae

Subfamília ANOPHELINAE: Gênero Anopheles Meigen, 1818; Subfamília CULICINAE: Tribo AEDEOMYIINI: Gênero Aedeomyia Theobald, 1901; Tribo AEDINI: Gênero Aedes Meigen, 1818; Gênero Haemagogus Williston, 1896; Gênero Psorophora Robineau-Desvoidy, 1827; Tribo CULICINI: Gênero Culex Linnaeus, 1758; Gênero Deinocerites Theobald, 1901; Tribo MANSONIINI: Gênero Coquillettidia Dyar, 1905; Gênero Mansonia Blanchard, 1901; Tribo ORTHO-PODOMYIINI: Gênero Orthopodomyia Theobald, 1904; Tribo SABETHINI: Gênero Limatus Theobald, 1901; Gênero Phoniomyia Theobald, 1903; Gênero Runchomyia Theobald, 1903; Gênero Sabethes Robineau-Desvoidy, 1827; Gênero Shannoniana Lane e Cerqueira, 1942; Gênero Trichoprosopon Theobald, 1901; Gênero Wyeomyia Theobald, 1901; Tribo URANOTAENIINI: Gênero Uranotaenia Lynch Arribalzaga, 1891.

Contribuição para o conhecimento dos parasitos de peixes do litoral do Estado da Guanabara - parte II

Neste presente trabalho os autores criam uma nova espécie para o subgênero Plagioporus (Plagioporus) Stafford, 1904, P. (P.) dollfusi sp. n. fica no grupo "b" da distribuição de travassos & cols. (1966), mais se aproximando de P. (P.) multilobatus Travassos & cols. 1966, distinguindo-se principalmente por possuir o limite anterior dos vitelinos na zona acetabular, poro genital bifurcal, bolsa do cirro alcançando a zona acetabular e ovos menores. Apresentam como novas ocorrências Enenterum pimelopteri Nagaty 1942 e Pseudopecoelus priacanthi (Mac Callum, 1921) manter, 1947. Apresentam ainda Garrupa sp. como novo hospedeiro de Pseudopecoelus priacanthi. Referem a presença de Hysterolecitha elongata manter, 1931, Bucephalus varicus manter, 1940, Metadena spectanda travassos, Freitas & Bührnheim, 1967 e uma fêmea jovem de Echinorhynchideae Southwell & Macfie, 1925 (Acanthocephala).

Trypanosoma cruzi: inhibition of alpha-hydroxyacid dehydrogenase isozyme II by N-allyl and N-propyl oxamates and their effects on intact epimastigotes

N-allyl (NAOx) and N-propyl (NPOx) oxamates were designed as inhibitors of alpha-hydroxyacid dehydrogenase (HADH) isozyme II from Trypanosoma cruzi. The kinetic studies showed that NAOx and NPOx were competitive inhibitors of HADH-isozyme II (Ki = 72 µM, IC50 = 0.33 mM and 70 µM, IC50 = 0.32 mM, respectively). The attachment of the allylic and propylic chains to nitrogen of the competitive inhibitor oxamate (Ki = 0.91 mM, IC50 = 4.25 mM), increased 12.6 and 13-folds respectively, the affinity for T. cruzi HADH-isozyme II. NAOx and NPOx were selective inhibitors of HADH-isozyme II, because other T. cruzi dehydrogenases were not inhibited by these substances. Since HADH-isozyme II participates in the energy metabolism of T. cruzi, a trypanocidal effect can be expected with these inhibitors. However, we were not able to detect any trypanocidal activity with these oxamates. When the corresponding ethyl esters of N-allyl (Et-NAOx) and N-propyl (Et-NPOx) oxamates were tested as a possible trypanocidal prodrugs, in comparison with nifurtimox and benznidazole, the expected trypanocidal effects were obtained.

A química na educação da Princesa Isabel

The private archive of the Brazilian Imperial Family holds a wealth of little known documents about the education of the daughters of Emperor D. Pedro II, especially of the eldest, Isabel, Princess Imperial. Science, particularly chemistry, for which her father had a particular fondness, occupied an important place in the girl's education. The study of these documents sheds a new light on the contrast between female education in the country in general, during most of the 19th century, and the careful upbringing envisaged by the Emperor for his future successor.

Impregnação do ácido 12-tungstofosfórico em sílica - parte II: efeito de diferentes solventes na impregnação e atividade catalítica na esterificação metílica de ácido esteárico

Materials obtained by the immobilization of 12-tungstophosphoric acid (PTA) on silica using the method of impregnation with excess solution in distinct solvents (aqueous HCl, methanol:H2O, and acetonitrile) were evaluated for use as catalysts in the methyl esterification of stearic acid. Optimum conditions were established for the impregnation of 0.5 g (w/w) of PTA on amorphous silica, under stirring at 150 rpm for 24 h, using 20 mL of 0.1 mol L-1 HCl as the solvent. After calcination at 200 ºC, high conversions were obtained under mild reaction conditions, resulting in high turnover numbers. The catalyst was evaluated in ten catalytic cycles of use, where the activity was reduced only slightly, attesting its stability and the possibility to apply it to industrial production of methylesters.