Tem orixá no samba: Clara Nunes e a presença do candomblé e da umbanda na música popular brasileira

Algumas informações sobre as religiões afro-brasileiras (candomblé e umbanda) nos chegam por meios como a indústria fonográfica, o rádio e a televisão. Nesse cenário, a música popular brasileira (MPB) ocupa importante papel de divulgadora dessa religiosidade. Em vista disso, nesse trabalho procuro interpretar os modos pelos quais os valores dessas religiões aparecem na MPB tendo como campo empírico a produção artística de Clara Nunes (análise de letra de música, da performance em shows, clipes e apresentações em programas de TV, assim como dos símbolos escolhidos na divulgação de seu trabalho, presentes em encartes e capas de LPs).

Protein folding: a perspective for biology, medicine and biotechnology

At the present time, protein folding is an extremely active field of research including aspects of biology, chemistry, biochemistry, computer science and physics. The fundamental principles have practical applications in the exploitation of the advances in genome research, in the understanding of different pathologies and in the design of novel proteins with special functions. Although the detailed mechanisms of folding are not completely known, significant advances have been made in the understanding of this complex process through both experimental and theoretical approaches. In this review, the evolution of concepts from Anfinsen's postulate to the "new view" emphasizing the concept of the energy landscape of folding is presented. The main rules of protein folding have been established from in vitro experiments. It has been long accepted that the in vitro refolding process is a good model for understanding the mechanisms by which a nascent polypeptide chain reaches its native conformation in the cellular environment. Indeed, many denatured proteins, even those whose disulfide bridges have been disrupted, are able to refold spontaneously. Although this assumption was challenged by the discovery of molecular chaperones, from the amount of both structural and functional information now available, it has been clearly established that the main rules of protein folding deduced from in vitro experiments are also valid in the cellular environment. This modern view of protein folding permits a better understanding of the aggregation processes that play a role in several pathologies, including those induced by prions and Alzheimer's disease. Drug design and de novo protein design with the aim of creating proteins with novel functions by application of protein folding rules are making significant progress and offer perspectives for practical applications in the development of pharmaceuticals and medical diagnostics.

Repercussions of a sleep medicine outreach program

Despite the high prevalence of sleep disorders, many healthcare professionals and lay people have little knowledge of Sleep Medicine. Mindful of such a reality, in 2001 the Sleep Institute of the Associação Fundo de Incentivo à Psicofarmacologia launched a campaign to increase Sleep Medicine awareness. Media features, exhibitions, inserts, and classes were used to reach 2,000,000 people and 55,000 healthcare professionals during the period from 2001 to 2004. To evaluate this program, we compared data for polysomnography referrals to the Institute in 2000 and in 2004. A total of 8805 referrals were evaluated (2000: 2164; 2004: 6641). Over the 4 years of the program, the number of beds increased by 43%; more women were referred (31 vs 37%; P < 0.001), mainly with a diagnostic hypothesis of sleep-disorder breathing (SDB). SDB was the most frequent diagnostic hypothesis in 2000 and 2004. In 2004 there were fewer referrals without a diagnostic hypothesis (27 vs 21%; P < 0.001) and for controlling surgically treated SDB (2.3 vs 1.6%; P < 0.05), and an increase in the following diagnostic hypotheses: non-invasive treatment of SDB (8.3 vs 12.3%; P < 0.001) and insomnia (3.5 vs 6.5%; P < 0.001). Insomnia diagnostic hypothesis was better correlated with SDB on referral documents in 2004 and less with a diagnostic hypothesis of limb movement disturbance. The program helped increase polysomnography referrals, particularly among women. Healthcare professionals appear to have a more developed understanding of sleep disorders.

Evaluation of cardiovascular toxicity of carbon nanotubes functionalized with sodium hyaluronate in oral regenerative medicine

It has been demonstrated that carbon nanotubes (CNTs) associated with sodium hyaluronate (HY-CNTs) accelerate bone repair in the tooth sockets of rats. Before clinical application of HY-CNTs, it is important to assess their biocompatibility. Moreover, cardiac toxicity may be caused by the translocation of these particles to the blood stream. The aim of this study was to evaluate possible changes in cardiovascular function in male Wistar rats whose tooth sockets were treated with either CNTs or HY-CNTs (100 μg/mL, 0.1 mL). Blood pressure and heart rate were monitored in conscious rats 7 days after treatment. Cardiac function was evaluated using the Langendorff perfusion technique. The data showed no changes in blood pressure or heart rate in rats treated with either CNTs or HY-CNTs, and no significant changes in cardiac function were found in any of the groups. To confirm these findings, experiments were conducted in rats injected intraperitoneally with a high concentration of either CNTs or HY-CNTs (0.75 mg/kg). The same parameters were analyzed and similar results were observed. The results obtained 7 days following injection indicate that the administration of low concentrations of CNTs or HY-CNTs directly into tooth sockets did not cause any significant change in cardiovascular function in the rats. The present findings support the possibility of using these biocomposites in humans.

Starter cultures used in probiotic dairy product preparation and popular probiotic dairy drinks

Dairy products that contain probiotic bacteria are those that are produced with various fermentation methods, especially lactic acid fermentation, by using starter cultures and those that have various textures and aromas. Fermented dairy products are popular due to their differences in taste and their favourable physiological effects. Today, fermented dairy beverages in general are produced locally by using traditional methods. Recently, due to the increased demand for natural nutrients and probiotic products, fermented dairy beverages have reached a different position and are considered to have an important impact on human health and nutrition. In this article, probiotic bacteria and functional dairy products that are produced by using probiotic bacteria are discussed.

Diabo e cultura popular

O presente trabalho focaliza a figura do diabo participando de duas expressões da chamada cultura popular medieval. Por meio de espetáculos como o Carnaval, a Festa dos Loucos, a Festa do Asno, procurei aprender, através da figura demoníaca, o intercâmbio entre duas formas de cultura - uma, séria, religiosa, feudal - relacionada com o mundo das instituições medievais - outra, cômica, irreverente, profana - ligada ao mundo medieval não institucionalizado.

Science and the values of popular movements

First an overall view is provided of Lacey’s ideas concerning science in its relation with the values of popular movements, and of the World Social Forum. Then, as an exercise in the building of conceptual bridges betweeen philosophical and political discourses about science, an analysis is provided of a speech delivered by Brazil’s new minister for science and technology in the occasion of his taking office.

A cooriginariedade entre direitos humanos e soberania popular: a crítica de Habermas a Kant e Rousseau

O texto busca compreender e avaliar as influências das filosofias políticas de Rousseau e Kant no pensamento habermasiano. Ele se atém sobretudo à ideia fundamental de Direito e democracia, segundo a qual há uma cooriginariedade lógica entre direitos humanos, interpretados como direitos fundamentais de liberdade individual, e a soberania popular, interpretada como direitos políticos de participação e comunicação, no processo de formação pública da opinião e vontade. Defende-se que a crítica habermasiana a Rousseau e a Kant se deve ao projeto de radicalização da democracia, para o qual as contribuições dos dois filósofos apresentam ainda alguns obstáculos. Porém, ao mesmo tempo, pode-se dizer que, segundo Habermas, a contribuição de um serve para sanar os problemas presentes na contribuição do outro.

Propostas de educação popular em Campinas: "as aulas noturnas"

Utilizando-se da pesquisa realizada em escritos da época, década de 1870, como jornais e almanaques, e da documentação encontrada sobre a fundação das "aulas noturnas", mantidas pela Sociedade Propagadora de Instrução, em Campinas, pretende-se conceituar a educação oferecida por essa escola como além do objetivo primeiro de toda e qualquer educação elementar, a alfabetização. Nela, esperava-se que as crianças e os adultos, ao se formarem, fossem inseridos em uma nova sociedade que se acreditava em formação. Assim, o artigo busca encontrar na educação a formação de homem, mundo e sociedade que a elite cafeicultora propunha para essa camada pobre presente no então espaço urbano nascente.