1 resultado para ACTIN-BINDING PROTEINS
em Brunel University
Filtro por publicador
- KUPS-Datenbank - Universität zu Köln - Kölner UniversitätsPublikationsServer (1)
- ABACUS. Repositorio de Producción Científica - Universidad Europea (1)
- Aberdeen University (1)
- Aberystwyth University Repository - Reino Unido (2)
- Academic Archive On-line (Stockholm University; Sweden) (2)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (1)
- Adam Mickiewicz University Repository (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (7)
- Aquatic Commons (1)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (11)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (4)
- Aston University Research Archive (15)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (13)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (21)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (56)
- Brock University, Canada (2)
- Brunel University (1)
- Bucknell University Digital Commons - Pensilvania - USA (1)
- CaltechTHESIS (10)
- Cambridge University Engineering Department Publications Database (1)
- CentAUR: Central Archive University of Reading - UK (19)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (16)
- Cochin University of Science & Technology (CUSAT), India (1)
- Coffee Science - Universidade Federal de Lavras (1)
- CORA - Cork Open Research Archive - University College Cork - Ireland (4)
- Deakin Research Online - Australia (16)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (9)
- Digital Commons at Florida International University (3)
- DigitalCommons@The Texas Medical Center (57)
- DRUM (Digital Repository at the University of Maryland) (2)
- Duke University (59)
- Glasgow Theses Service (1)
- Helda - Digital Repository of University of Helsinki (27)
- Indian Institute of Science - Bangalore - Índia (52)
- Instituto Gulbenkian de Ciência (5)
- Instituto Politécnico do Porto, Portugal (2)
- National Center for Biotechnology Information - NCBI (229)
- Portal de Revistas Científicas Complutenses - Espanha (1)
- QSpace: Queen's University - Canada (2)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (72)
- Queensland University of Technology - ePrints Archive (63)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (1)
- Repositório do Centro Hospitalar de Lisboa Central, EPE - Centro Hospitalar de Lisboa Central, EPE, Portugal (1)
- Repositório Institucional da Universidade de Aveiro - Portugal (2)
- Repositório Institucional da Universidade de Brasília (1)
- Repositorio Institucional de la Universidad Pública de Navarra - Espanha (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (50)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (2)
- School of Medicine, Washington University, United States (1)
- Universidad del Rosario, Colombia (1)
- Universidad Politécnica de Madrid (7)
- Universidade de Lisboa - Repositório Aberto (1)
- Universidade Federal do Rio Grande do Norte (UFRN) (10)
- Universita di Parma (1)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (3)
- Université de Lausanne, Switzerland (17)
- Université de Montréal (2)
- Université de Montréal, Canada (24)
- Université Laval Mémoires et thèses électroniques (1)
- University of Queensland eSpace - Australia (31)
- University of Washington (2)
Resumo:
Since its identification in the 1990s, the RNA interference (RNAi) pathway has proven extremely useful in elucidating the function of proteins in the context of cells and even whole organisms. In particular, this sequence-specific and powerful loss-of-function approach has greatly simplified the study of the role of host cell factors implicated in the life cycle of viruses. Here, we detail the RNAi method we have developed and used to specifically knock down the expression of ezrin, an actin binding protein that was identified by yeast two-hybrid screening to interact with the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) spike (S) protein. This method was used to study the role of ezrin, specifically during the entry stage of SARS-CoV infection.