2 resultados para diagnostic process

em Digital Commons at Florida International University


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We presented a unique case of a high school athlete who suffered from a coracoid process fracture following a collision with an opposing player. This fracture is commonly misdiagnosed as a clavicular fracture or AC joint sprain. Initial radiographic examination may fail to identify the fracture site. Understanding the clinical features of this injury is an important prerequisite to its overall management. Any misdiagnosis or alteration from the appropriate course of treatment can inhibit return to play and may be avoided by using indicated diagnostic evaluation tools.

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Nanoparticles have enormous potential in diagnostic and therapeutic studies. We have demonstrated that the amyloid beta mixed with and conjugated to dihydrolipoic acid- (DHLA) capped CdSe/ZnS quantum dots (QDs) of size approximately 2.5 nm can be used to reduce the fibrillation process. Transmission electron microscopy (TEM) and atomic force microscopy (AFM) were used as tools for analysis of fibrillation. There is a significant change in morphology of fibrils when amyloid β (1–42) (Aβ (1–42)) is mixed or conjugated to the QDs. The length and the width of the fibrils vary under modified conditions. Thioflavin T (ThT) fluorescence supports the decrease in fibril formation in presence of DHLA-capped QDs.