Information Discovery on Electronic Health Records Using Authority Flow Techniques

Background As the use of electronic health records (EHRs) becomes more widespread, so does the need to search and provide effective information discovery within them. Querying by keyword has emerged as one of the most effective paradigms for searching. Most work in this area is based on traditional Information Retrieval (IR) techniques, where each document is compared individually against the query. We compare the effectiveness of two fundamentally different techniques for keyword search of EHRs. Methods We built two ranking systems. The traditional BM25 system exploits the EHRs' content without regard to association among entities within. The Clinical ObjectRank (CO) system exploits the entities' associations in EHRs using an authority-flow algorithm to discover the most relevant entities. BM25 and CO were deployed on an EHR dataset of the cardiovascular division of Miami Children's Hospital. Using sequences of keywords as queries, sensitivity and specificity were measured by two physicians for a set of 11 queries related to congenital cardiac disease. Results Our pilot evaluation showed that CO outperforms BM25 in terms of sensitivity (65% vs. 38%) by 71% on average, while maintaining the specificity (64% vs. 61%). The evaluation was done by two physicians. Conclusions Authority-flow techniques can greatly improve the detection of relevant information in EHRs and hence deserve further study.

Web Based Bicycle Trip Planning for Broward County, Florida

To promote the use of bicycle transportation mode in times of increasing urban traffic congestion, Broward County Metropolitan Planning Organization funded the development of a Web-based trip planner for cyclists. This presentation demonstrates the integration of the ArcGIS Server 9.3 environment with the ArcGIS JavaScript Extension for Google Maps API and the Google Local Search Control for Maps API. This allows the use of Google mashup GIS functionality, i.e., Google local search for selection of trip start, trip destination, and intermediate waypoints, and the integration of Google Maps base layers. The ArcGIS Network Analyst extension is used for the route search, where algorithms for fastest, safest, simplest, most scenic, and shortest routes are imbedded. This presentation also describes how attributes of the underlying network sources have been combined to facilitate the search for optimized routes.

MIUS News: Maps and Imagery User Services @ FIU Green Library: Vol. 1, Issue 1 2007

Fall 2007 Newsletter for FIU's Maps and Imagery User Services department.

MUIS News: Maps and User Imagery Services @ FIU Green Library Vol. 2, Issue 1 2008

Florida International University's Fall 2008 Map and User Imagery Services Newsletter.

MIUS News: Maps and Imagery User Services @ FIU Green Library: Vol. 2, Issue 2 Spring 2009

Florida International University's Spring 2009 Map and User Imagery Services Newsletter.

MIUS News: Maps and Imagery User Services @ FIU Green Library: Vol. 3, Issue 1 Fall 2009

Florida International University's Fall 2009 Map and User Imagery Services Newsletter.

MIUS News: Maps and Imagery User Services @ FIU Green Library: Vol. 3, Issue 2 Fall 2009

Florida International University's Fall 2009 Map and User Imagery Services Newsletter; Vol. 3, issue 2.

MIUS News: Maps and Imagery User Services @ FIU Green Library: Vol. 3, Issue 2, Spring 2010

Florida International University's Spring 2010 Map and User Imagery Services Newsletter.

MIUS News: Maps and Imagery User Services @ FIU Green Library: Vol. 4, Issue 1 Fall 2012

Florida International University's Fall 2012 Map and User Imagery Services Newsletter.

MIUS News: Maps and Imagery User Services @ FIU Green Library: Vol. 4, Issue 2 Spring/Summer 2013

Florida International University's Spring/Summer 2013 Map and User Imagery Services Newsletter.

Coral Gables Virtual History

Florida International University has partnered with the City of Coral Gables to create a geospatially-enabled Virtual Historic City. With this tool, users may navigate to any point in the city at a selected time period (e.g. the Biltmore Hotel from the 1920s to 1940s) and experience the city as it was, through a wide variety of cultural artifacts and textual materials. A virtual walking tour of Coral Gables was also created, which includes an audio narration and 3D simulations providing the façades of historic buildings and landscape. Students, educators, historians, public policy administrators, architects, sociologists, environmental analysts, urban planners, and the general public can explore over 8,000 historical documents, photographs, oral histories, and maps that have been spatially registered to their relevant locations and time.

Serial evolutionary networks of within-patient HIV-1 sequences reveal patterns of evolution of X4 strains

Background The HIV virus is known for its ability to exploit numerous genetic and evolutionary mechanisms to ensure its proliferation, among them, high replication, mutation and recombination rates. Sliding MinPD, a recently introduced computational method [1], was used to investigate the patterns of evolution of serially-sampled HIV-1 sequence data from eight patients with a special focus on the emergence of X4 strains. Unlike other phylogenetic methods, Sliding MinPD combines distance-based inference with a nonparametric bootstrap procedure and automated recombination detection to reconstruct the evolutionary history of longitudinal sequence data. We present serial evolutionary networks as a longitudinal representation of the mutational pathways of a viral population in a within-host environment. The longitudinal representation of the evolutionary networks was complemented with charts of clinical markers to facilitate correlation analysis between pertinent clinical information and the evolutionary relationships. Results Analysis based on the predicted networks suggests the following:: significantly stronger recombination signals (p = 0.003) for the inferred ancestors of the X4 strains, recombination events between different lineages and recombination events between putative reservoir virus and those from a later population, an early star-like topology observed for four of the patients who died of AIDS. A significantly higher number of recombinants were predicted at sampling points that corresponded to peaks in the viral load levels (p = 0.0042). Conclusion Our results indicate that serial evolutionary networks of HIV sequences enable systematic statistical analysis of the implicit relations embedded in the topology of the structure and can greatly facilitate identification of patterns of evolution that can lead to specific hypotheses and new insights. The conclusions of applying our method to empirical HIV data support the conventional wisdom of the new generation HIV treatments, that in order to keep the virus in check, viral loads need to be suppressed to almost undetectable levels.