2 resultados para Prescrição farmacêutica
em Universidade Federal de Uberlândia
Resumo:
Based on the theoretical approach on the structure and functioning of the capitalist mode of production in the light of the Marxian perspective of Althusser, Poulanzas and Saes, the objective of this study is to describe and analyze the career path of the deployment process of education workers public state of Minas Gerais, in the context of neoliberal educational policies implemented in the period 2003-2014. This study will make use of the techniques of bibliographical and documentary research; to do so, we will try, at first, to establish the correspondence of this peculiar mode of production (capitalism) and the bourgeois state, trying to understand their legal and political structure, characterized by the right and the bourgeois bureaucracy, highlighting the importance of the state apparatus to conditioning ideologies and their structures for prescription of social practices. In the second phase, we will present to the prevailing ideologies School appear in the form of speech and legal and governmental practices in today's society. Finally, we will seek to understand the applicability of the theory studied in the concrete reality of educational public policies implemented in Minas Gerais, in the perspective of democratic government, modernized and efficient state, as opposed to the interests of the Single Union of Education Workers (Sind-UTE / MG). Thus, we can conclude that our work object is to analyze the educational policies of the bourgeois state, focusing on career path in the context of Minas Gerais, from 2003 to 2014, and its social, political and economic education for workers Minas Gerais state and the society today.
Resumo:
Oral route of administration is considered to be the most comfortable, safe and greater adaptation for patients. But, oral route presents some disadvantages such as drugs bioavailability and side effects on the stomach. Some technologies are studied to soften and/or resolve these problems, such as coating with polymeric films, which are able to protect the pharmaceutical form of the acid stomachic environment and to act in the drug release, and mucoadhesive systems, which allow the pharmaceutical form remains a greater time interval in the intestine, increasing the effectiveness of the drug. Cellulose triacetate (CTA) films were produced from cellulose extracted from sugar cane bagasse. The films were prepared with different morphologies (with and without water, acting as non-solvent) and concentrations (3, 6.5 and 10%) of CTA and characterized using scanning electron microscopy (SEM), water vapor permeability (WVP), puncture resistance (PR), enzymatic digestion (DE), and mucoadhesive force evaluation (MF). Microscopy showed the formation of symmetric and asymmetric morphologies. WVP data showed that more concentrated films have higher values for WVP; moreover, asymmetric films had higher values than symmetric films. PR measurements showed that symmetric membranes are more resistant than asymmetric ones. More concentrated films were also more puncture resistant, except for symmetric membranes with CTA concentrations of 6.5 and 10% that did not show significant differences. All of the films presented large mucoadhesive capacities independent of their morphology and CTA concentration. From the results of WVP and RP, a symmetric filme with 6.5% CTA showed better ability and mechanical resistance, therefore, was selected to serve as coating of gellan gum (GG) particles incorporating ketoprofen (KET), which was confirmed by SEM. The selected film presented low values in measurements of the swelling index (SI) and in a dissolution test (DT). TGA analysis showed that the CTA coating does not influence the thermal stability of the particles and there is no incompatibility evidence between CTA, GG and KET. Coated particles released 100% of the ketoprofen in 24 h, while uncoated particles released the same amount in 4 h. The results of this study highlight the potential of CTA in the development of new controlled oral delivery systems.