Intelligent Computations for Flood Monitoring

Floods represent the most devastating natural hazards in the world, affecting more people and causing more property damage than any other natural phenomena. One of the important problems associated with flood monitoring is flood extent extraction from satellite imagery, since it is impractical to acquire the flood area through field observations. This paper presents a method to flood extent extraction from synthetic-aperture radar (SAR) images that is based on intelligent computations. In particular, we apply artificial neural networks, self-organizing Kohonen’s maps (SOMs), for SAR image segmentation and classification. We tested our approach to process data from three different satellite sensors: ERS-2/SAR (during flooding on Tisza river, Ukraine and Hungary, 2001), ENVISAT/ASAR WSM (Wide Swath Mode) and RADARSAT-1 (during flooding on Huaihe river, China, 2007). Obtained results showed the efficiency of our approach.

Theoretical Hyperbolic Model of a Partial Agonism: Explicit Formulas for Affinity, Efficacy and Amplification

The quantitative analysis of receptor-mediated effect is based on experimental concentration-response data in which the independent variable, the concentration of a receptor ligand, is linked with a dependent variable, the biological response. The steps between the drug–receptor interaction and the subsequent biological effect are to some extent unknown. The shape of the fitting curve of the experimental data may give some in-sights into the nature of the concentration–receptor–response (C-R-R) mechanism. It can be evaluated by non-linear regression analysis of the experimental data points of the independent and dependent variables, which could be considered as a history of the interaction between the drug and receptors. However, this information is not enough to evaluate such important parameters of the mechanism as the dissociation constant (affinity) and efficacy. There are two ways to provide more detailed information about the C-R-R mechanism: (i) an experimental way for obtaining data with new or