4 resultados para Molecular modeling algorithms
em Bulgarian Digital Mathematics Library at IMI-BAS
Resumo:
Accelerated probabilistic modeling algorithms, presenting stochastic local search (SLS) technique, are considered. General algorithm scheme and specific combinatorial optimization method, using “golden section” rule (GS-method), are given. Convergence rates using Markov chains are received. An overview of current combinatorial optimization techniques is presented.
Resumo:
The polyparametric intelligence information system for diagnostics human functional state in medicine and public health is developed. The essence of the system consists in polyparametric describing of human functional state with the unified set of physiological parameters and using the polyparametric cognitive model developed as the tool for a system analysis of multitude data and diagnostics of a human functional state. The model is developed on the basis of general principles geometry and symmetry by algorithms of artificial intelligence systems. The architecture of the system is represented. The model allows analyzing traditional signs - absolute values of electrophysiological parameters and new signs generated by the model – relationships of ones. The classification of physiological multidimensional data is made with a transformer of the model. The results are presented to a physician in a form of visual graph – a pattern individual functional state. This graph allows performing clinical syndrome analysis. A level of human functional state is defined in the case of the developed standard (“ideal”) functional state. The complete formalization of results makes it possible to accumulate physiological data and to analyze them by mathematics methods.
Resumo:
In this paper we propose a model of encoding data into DNA strands so that this data can be used in the simulation of a genetic algorithm based on molecular operations. DNA computing is an impressive computational model that needs algorithms to work properly and efficiently. The first problem when trying to apply an algorithm in DNA computing must be how to codify the data that the algorithm will use. In a genetic algorithm the first objective must be to codify the genes, which are the main data. A concrete encoding of the genes in a single DNA strand is presented and we discuss what this codification is suitable for. Previous work on DNA coding defined bond-free languages which several properties assuring the stability of any DNA word of such a language. We prove that a bond-free language is necessary but not sufficient to codify a gene giving the correct codification.
Resumo:
Summarizing the accumulated experience for a long time in the polyparametric cognitive modeling of different physiological processes (electrocardiogram, electroencephalogram, electroreovasogram and others) and the development on this basis some diagnostics methods give ground for formulating a new methodology of the system analysis in biology. The gist of the methodology consists of parametrization of fractals of electrophysiological processes, matrix description of functional state of an object with a unified set of parameters, construction of the polyparametric cognitive geometric model with artificial intelligence algorithms. The geometry model enables to display the parameter relationships are adequate to requirements of the system approach. The objective character of the elements of the models and high degree of formalization which facilitate the use of the mathematical methods are advantages of these models. At the same time the geometric images are easily interpreted in physiological and clinical terms. The polyparametric modeling is an object oriented tool possessed advances functional facilities and some principal features.