GPCRTree:online hierarchical classification of GPCR function

G protein-coupled receptors (GPCRs) play important physiological roles transducing extracellular signals into intracellular responses. Approximately 50% of all marketed drugs target a GPCR. There remains considerable interest in effectively predicting the function of a GPCR from its primary sequence.

Can diversity amongst learners improve online object tracking?

We present a novel analysis of the state of the art in object tracking with respect to diversity found in its main component, an ensemble classifier that is updated in an online manner. We employ established measures for diversity and performance from the rich literature on ensemble classification and online learning, and present a detailed evaluation of diversity and performance on benchmark sequences in order to gain an insight into how the tracking performance can be improved. © Springer-Verlag 2013.