6 resultados para Salisbury, Robert Cecil, Earl of, 1563-1612.

em Aston University Research Archive


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Almost everyone who has an email account receives from time to time unwanted emails. These emails can be jokes from friends or commercial product offers from unknown people. In this paper we focus on these unwanted messages which try to promote a product or service, or to offer some “hot” business opportunities. These messages are called junk emails. Several methods to filter junk emails were proposed, but none considers the linguistic characteristics of junk emails. In this paper, we investigate the linguistic features of a corpus of junk emails, and try to decide if they constitute a distinct genre. Our corpus of junk emails was build from the messages received by the authors over a period of time. Initially, the corpus consisted of 1563, but after eliminating the duplications automatically we kept only 673 files, totalising just over 373,000 tokens. In order to decide if the junk emails constitute a different genre, a comparison with a corpus of leaflets extracted from BNC and with the whole BNC corpus is carried out. Several characteristics at the lexical and grammatical levels were identified.

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Objective: To determine the efficacy of cholinesterase inhibitors (ChEIs) in improving the behavioral and psychological symptoms of dementia (BPSD) in patients with Alzheimer’s disease (AD). Data sources: We searched MEDLINE, Cochrane Registry, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) from 1966 to 2007. We limited our search to English Language, full text, published articles and human studies. Data extraction: We included randomized, double-blind, placebo-controlled trials evaluating the efficacy of donepezil, rivastigmine, or galantamine in managing BPSD displayed by AD patients. Using the United States Preventive Services Task Force (USPSTF) guidelines, we critically appraised all studies and included only those with an attrition rate of less than 40%, concealed measurement of the outcomes, and intention to treat analysis of the collected data. All data were imputed into pre-defined evidence based tables and were pooled using the Review Manager 4.2.1 software for data synthesis. Results: We found 12 studies that met our inclusion criteria but only nine of them provided sufficient data for the meta-analysis. Among patients with mild to severe AD and in comparison to placebo, ChEIs as a class had a beneficial effects on reducing BPSD with a standard mean difference (SMD) of -0.10 (95% confidence interval [CI]; -0.18, -0.01) and a weighted mean difference (WMD) of -1.38 neuropsychiatry inventory point (95% CI; -2.30, -0.46). In studies with mild AD patients, the WMD was -1.92 (95% CI; -3.18, -0.66); and in studies with severe AD patients, the WMD was -0.06 (95% CI; -2.12, +0.57). Conclusion: Cholinesterase inhibitors lead to a statistical significant reduction in BPSD among patients with AD, yet the clinical relevance of this effect remains unclear.

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Central aspects of new regime for taxation of intangible assets introduced by FA 2002 which seeks to align tax treatment with accounting treatment of intellectual property

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The Models@run.time workshop (MRT) series offers a discussion forum for the rising need to leverage modeling techniques at runtime for the software of the future. MRT has become a mature research topic, which is, e.g., reflected in separate sessions at conferences covering MRT approaches only. The target venues of the workshops audience changed from workshops to conferences. Hence, new topics in the area of MRT need to be identified, which are not yet mature enough for conferences. In consequence, the main goal of this edition was to reflect on the past decade of the workshop's history and to identify new future directions for the workshop.

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