Reaching the bar

Reports on the issues addressed at the Bar Council-Aimhigher widening participation conference, "How to get to the Bar" held at St Philips Chambers, Birmingham on July 12, 2010 and attended by 80 sixth form students.

Unrepeatered DP-QPSK transmission over 350 km standard fibre using URFL based amplification

Unrepeatered 115.6 Gbit/s per channel WDM DP-QPSK transmission with novel URFL based amplification is demonstrated. Transmission of 1.4 Tb/s was possible in 350 km link and 2.2 Tb/s was achieved in 325 km without employing ROPA or speciality fibres.

Unrepeatered DP-QPSK transmission over 352.8 km SMF using random DFB fiber laser amplification

Unrepeatered 100 Gbit/s per channel wave-divisionmultiplexed dual-polarization-QPSK transmission with random distributed feedback fiber laser-based Raman amplification using fiber Bragg grating is demonstrated. Transmission of 1.4 Tb/s (14 × 100 Gbit/s) was possible in 352.8 km link and 2.2 Tb/s (22 × 100 Gbit/s) was achieved in 327.6 km without employing remote optically pumped amplifier or speciality fibers.

Obstructive sleep apnoea is associated with sight threatening retinopathy and predicts the developement of preproliferative and proliferative retinopathy in patients with type 2 diabetes:a longitudinal analysis

troduct I on . An observational longitudinal study. P ur P ose . Assess the relationship between obstructive sleep apnoea (OSA) and DR cross-sectionally and longitudinally. M ethods . Adults with Type 2 diabetes mellitus (T2DM), who were re - cruited from a hospital-based diabetes clinic in the UK. Patients with pre-existing OSA, end-stage renal disease and non-diabetic retinopa - thy were excluded. OSA (apnoea hypopnea index ≥ 5 events/hour) was assessed by a single overnight home-based cardio-respiratory study (Alice PDX, Philips Respironics, USA). DR was assessed us - ing retinal images between 2007 and 2012. Sight threatening diabetic retinopathy (STDR) was defined as presence of pre-proliferative or proliferative DR, maculopathy or photocoagulation. Advanced DR was defined as pre-proliferative or proliferative DR. r esults . 199 patients were included (57.3% (n=114) men, 47.7% (n=95) White Europeans). STDR and OSA prevalence were 38.7% (n=77) and 62.8% respectively. A t b A sel I ne . STR prevalence was higher in patients with OSA (OSA+) compared to those without OSA (OSA-) [48.8% n=61 vs. 21.6% n=16, p<0.001]. After adjustment for confounders, OSA remained independently associated with STR (OR 3.7, 95% CI 1.6-8.9, p=0.006), maculopathy (OR 4.5, 95% CI 1.8-11.4, p=0.002) and advanced DR (OR 3.9, 95% CI 1.02-15.3, p=0.047). Mild and moderate to severe OSA were independently associated with STR and maculopathy and only moderate to severe OSA was associated with advanced DR following adjustment for con - founders. l ong I tud I n A lly . Over the follow-up period of (4.4±1 years), more OSA+ patients progressed from no or background DR to advanced DR (15.3% (n=17) vs. 3% (n=2), p=0.01). OSA was an independent pre - dictor of advanced DR development after adjustment for confounders (OR 6.6, 95% CI 1.2-35.1, p=0.03). OSA did not predict the develop - ment of maculopathy. c onclus I ons . OSA is independently associated with STR and predicts the development of preproliferative and proliferative DR. Intervention - al studies are needed to assess the impact of OSA treatment on DR.