Organic reactions in ionic liquids: ionic liquid-accelerated cyclocondensation of alpha-tosyloxyketones with 2-aminopyridine

The room temperature ionic liquid it-butylpyridinium tetrafluoroborate (BPyBF4) is used as a `green' recyclable alternative to classical molecular solvents for the cyclocondensation of alpha-tosyloxyketones with 2-aminopyridine. Significant rate enhancements and improved yields have been observed.