2 resultados para urinary 2,5-hexanodione determination


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En el centro de salud Nº 66 “El Mirador" Rivadavia, se observó, un grupo etario, (niños de 2-5 años), con un marcado déficit nutricional. Esto marcó un interés que lleva a investigar más profundo para determinar los factores que afectan a este grupo en particular. Los objetivos de este trabajo son: identificar factores que inciden en la desnutrición en niños de 2 a 5 años que asisten al centro de salud N° 66, analizar los recursos socio económico de la familia responsable de los niños, conocer hábitos alimenticios de la familia, determinar nivel cultural de los adultos responsables y establecer parámetros de grado de nutrición.

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Polybrominated diphenyl ethers (PBDEs) are considered persistent organic pollutants because of their ubiquity, persistence and bioaccumulation. Its harmful effects on human health and the environment, has led to its inclusion of the Stockholm Convention. Little information is found about PBDEs in abiotic systems of the South America in open literature. This paper reports the presence and concentration level of four PBDEs congeners in Mendoza River, Argentina. The selected PBDEs were: 2,2',4,4'-tetrabromodiphenyl ether (BDE-47), 2,2',4,4',5-pentabromodiphenyl ether (BDE-99), 2,2',4,4',6-pentabromodiphenyl ether (BDE- 100) and 2,2',4,4',5,5'-hexabromodiphenyl ether (BDE-153). The analytical methodology used was head space-solid phase micro extraction combined with gas chromatographymass spectrometry (HS-SPME-GC-MS/MS). Several variables, including pH, salting out, extraction technique type and extraction time were studied and optimized over the relative response the target analytes. The precision of HS-SPME-GC-MS/MS evaluated over five replicate, leading RSDs values <13%, detection limits (S/N=3) ranging from 0.03 pg ml-1 to 0.12 pg ml-1 and the calibration graph was linear with r2=0.9959. BDE-47 and BDE-100 were the predominant congeners found in the analyzed samples. Their concentrations ranged from not detected to 1.9 pg ml-1 and to 0.5 pg ml-1, respectively.