1 resultado para kinetic resolution of activated cyclopropanes
em Digital Knowledge Repository of Central Drug Research Institute
Filtro por publicador
- Repository Napier (1)
- Abertay Research Collections - Abertay University’s repository (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (4)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (3)
- Aquatic Commons (2)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (3)
- Archimer: Archive de l'Institut francais de recherche pour l'exploitation de la mer (1)
- Archive of European Integration (21)
- Aston University Research Archive (34)
- Biblioteca de Teses e Dissertações da USP (1)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (18)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (19)
- Biodiversity Heritage Library, United States (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (35)
- Boston University Digital Common (2)
- Brock University, Canada (9)
- Bulgarian Digital Mathematics Library at IMI-BAS (1)
- CaltechTHESIS (9)
- Cambridge University Engineering Department Publications Database (9)
- CentAUR: Central Archive University of Reading - UK (49)
- Center for Jewish History Digital Collections (7)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (94)
- Cochin University of Science & Technology (CUSAT), India (4)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (6)
- CORA - Cork Open Research Archive - University College Cork - Ireland (7)
- CUNY Academic Works (1)
- Deakin Research Online - Australia (17)
- Department of Computer Science E-Repository - King's College London, Strand, London (1)
- Digital Commons - Michigan Tech (1)
- Digital Knowledge Repository of Central Drug Research Institute (1)
- DigitalCommons@The Texas Medical Center (8)
- DRUM (Digital Repository at the University of Maryland) (1)
- Duke University (4)
- Greenwich Academic Literature Archive - UK (3)
- Harvard University (1)
- Helda - Digital Repository of University of Helsinki (2)
- Illinois Digital Environment for Access to Learning and Scholarship Repository (1)
- Indian Institute of Science - Bangalore - Índia (72)
- Institutional Repository of Leibniz University Hannover (1)
- Instituto Politécnico de Leiria (2)
- Instituto Politécnico de Santarém (2)
- Instituto Superior de Psicologia Aplicada - Lisboa (1)
- National Center for Biotechnology Information - NCBI (45)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (3)
- Publishing Network for Geoscientific & Environmental Data (105)
- QSpace: Queen's University - Canada (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (90)
- Queensland University of Technology - ePrints Archive (32)
- Repositório Alice (Acesso Livre à Informação Científica da Embrapa / Repository Open Access to Scientific Information from Embrapa) (1)
- Repositório Científico da Universidade de Évora - Portugal (3)
- Repositório Científico do Instituto Politécnico de Santarém - Portugal (1)
- Repositório digital da Fundação Getúlio Vargas - FGV (1)
- Repositorio Institucional da UFLA (RIUFLA) (1)
- Repositorio Institucional de la Universidad de Málaga (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (60)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (2)
- SAPIENTIA - Universidade do Algarve - Portugal (1)
- School of Medicine, Washington University, United States (4)
- Universidad Autónoma de Nuevo León, Mexico (3)
- Universidad de Alicante (15)
- Universidade Complutense de Madrid (3)
- Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP) (1)
- Universidade Federal de Uberlândia (1)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (3)
- Université de Lausanne, Switzerland (6)
- Université de Montréal (1)
- Université de Montréal, Canada (6)
- University of Michigan (65)
- University of Queensland eSpace - Australia (36)
- Worcester Research and Publications - Worcester Research and Publications - UK (1)
Resumo:
A one-pot, general synthesis of highly functionalized quateraryls through carbanion-induced, base-catalyzed ring transformation of 5,6-diaryl-2H-pyran-2-ones and core-substituted phenylacetones is delineated. These conversions were found to give diversely functionalized benzenes bearing peripheral aryl rings, some of which possess inherent atropisomerism. Exemplarily for one of the quateraryls, the optical resolution of the respective atropo-enantiomers by HPLC on a chiral phase and the assignment of their absolute axial configurations succeeded by LC-CD coupling in combination with semiempirical CNDO/S and TDDFT CD calculations. This synthetic approach offers – in a transition metal-free environment – high flexibility in the construction of quateraryls with the desired conformational freedom along the molecular axis, which may help in exploring and developing new potential ligands for asymmetric synthesis.