Social Cognition And Functional Brain Imaging: Extending The Broader Autism Phenotype

Evidence suggests that the social cognition deficits prevalent in autism spectrum disorders (ASDs) are widely distributed in first degree and extended relatives. This ¿broader autism phenotype¿ (BAP) can be extended into non-clinical populations and show wide distributions of social behaviors such as empathy and social responsiveness ¿ with ASDs exhibiting these behaviors on the lower ends of the distributions. Little evidence has previously shown relationships between self-report measures of social cognition and more objective tasks such as face perception in functional magnetic resonance imaging (fMRI) and event-related potentials (ERPs). In this study, three specific hypotheses were addressed: a) increased social ability, as measured by an increased Empathy Quotient, decreased Social Responsiveness Scale (SRS-A) score, and increased Social Attribution Task score, will predict increased activation of the fusiform gyrus in response to faces as compared to houses; b) these same measures will predict N170 amplitude and latency showing decreased latency and increased amplitude for faces as compared to houses with increased social ability; c) increased amygdala volume will predict increased fusiform gyrus activation when viewing faces as compared to houses. Findings supported all of the hypotheses. Empathy scores significantly predicted both right FFG activation [F(1,20) = 4.811, p = .041, ß = .450, R2 = 0.20] and left FFG activation [F(1,20) = 7.70, p = .012, ß = .537, R2 = 0.29]. Based on ERP results increased right lateralization face-related N170 was significantly predicted by the EQ [F(1,54) = 6.94, p = .011, ß = .338, R2 = 0.11]. Finally, total amygdala volume significantly predicted right [F(1,20) = 7.217, p = .014, ß = .515, R2 = 0.27] and left [F(1,20) = 36.77, p < .001, ß = .805, R2 = 0.65] FFG activation. Consistent with the a priori hypotheses, traits attributed to the BAP can significantly predict neural responses to faces in a non-clinical population. This is consistent with the face processing deficits seen in ASDs. The findings presented here contribute to the extension of the BAP from unaffected relatives of individuals with ASDs to the general population. These findings also give continued evidence in support of a continuous distribution of traits found in psychiatric illnesses in place of a traditional, dichotomous ¿all-or-nothing¿ diagnostic framework of neurodevelopmental and neuropsychiatric disorders.

Locational and Temporal Risk Associated With Campus Sexual Assault

The present study investigates the rates of victimization of sexual assault reported by undergraduates at Bucknell University. Specifically, the study aimed to determine where and when sexual assault took place, in order to pinpoint both temporal risks and locational risks associated with certain events on campus. Results of the survey were analyzed for victimization rates across class year, time of year, where victimization took place, as well as where victims and perpetrators met. Data for the study was gathered by means of anonymous survey, sent out to 1752 randomly selected undergraduates via email. Participants filled out the survey which asked if they had ever been sexually assaulted or committed a sexual assault during their past year studying at Bucknell. The results of the survey indicated that dormitories, fraternity houses, and off-campus student houses displayed significantly higher rates of victimization than other locations. In addition, increased risk of unwanted sexual contact in the fall semester was shown to be statistically significant. Moreover, results of the current study support that parties were statistically significant locations for meeting perpetrators of sexual assault. The results suggest that it may be beneficial to direct special attention towards campus sexual assault, specifically to certain locations, times of the year, and campus activities.