Nouvelle méthode d’analyse de l’exploration visuelle

The term visual field corresponds to the angular field of view that is seen by the eyes when they are fixed on a point straight-ahead. In neurological patients--e.g. stroke, trauma, or tumour patients--visual field function can be restricted, depending on lesion site and size. In contrast, the term "functional visual field" describes the area of visual field responsiveness under more ordinary viewing conditions. The visual exploration, i.e. the capacity to explore and analyze our visual world, is dependent on the integrity of the visual system and the oculomotor system which has to move the fovea from one object of interest to the next. In this paper, we present a new method to assess the functional visual field, conceptualized as the area that a patient actively scans with eye movements to detect predefined targets placed on everyday scenes. This method allows us to compare three levels of visual field function: (a) the spatial distribution of successful search (hits, i.e. which targets did the patient find?), (b) the spatial distribution of fixations (i.e. where did the patient preferentially search for targets?), and (c) the retinotopic level (i.e. the visual field assessed by perimetry). By integrating these three levels, one can evaluate functional outcomes of visual field disorders. Of particular importance is the question of how a patient compensates for a visual field loss with appropriate eye movements. A further clinical application of this method is the comparison of pre- with post-treatment data. Patients with visual field disorders usually undergo specific exploration trainings, aimed at enhancing the number and amplitude of saccades towards the region of the visual field deficit. The first experiences and clinical application with this method are presented here.

Relations between adolescents' self-evaluations, time perspectives, motivation for school and their achievement in different countries and at different ages

The present study focused on the relations between the self-efficacy, social self-concept, time perspectives, school investment and academic achievement of students in four different European countries and in different adolescence periods. A total of 1623 students completed questionnaires. The relations between the concepts proved not to be specific to the Western or to the former Communist bloc countries studied. The expected general decline in investment and academic achievement over the adolescence period showed up in all four countries studied. Contrary to our hypothesis, however, this decline could not be explained by growing influences of either social self-concept or time perspectives regarding personal development on their investment. In fact, the effects of social self-concept were strongest for the youngest adolescence group. Students’ social self-concept was the best predictor for their investment, while self-efficacy proved to predict academic achievement best in all adolescence periods.

Screening for lupus anticoagulant: improving the performance of the lupus-sensitive PTT-LA

Introduction: The aim of the present work was to verify whether calculating a ratio between clotting times obtained with the sensitive PTT-LA and a less sensitive activated partial thromboplastin time (aPTT)-reagent may represent a valuable aPTT-based screening strategy for lupus anticoagulants (LA). Methods: For the pilot study, plasma samples from normal subjects (n = 15) and from patients with LA (n = 10), therapeutic anticoagulation with vitamin K-antagonists (VKA) (n = 15) or unfractionated heparin (n = 15), coagulation factors deficiency (n = 16), and inhibitory antibodies against factor VIII or IX (n = 11) were studied. For the evaluation study, 1553 consecutive plasma samples from nonanticoagulated patients investigated for LA between January 2005 and December 2007 at our institution were studied. Following screening strategies were employed: Pathromtin-SL (aPTT-SL), PTT-LA (aPTT-LA), ratio aPTT-LA/aPTT-SL (aPTT-ratio), and Russell's viper venom (RVV) based LA-Check. LA positive samples were identified by mixing studies and diluted RVV confirmation test (LA-Check/LA-Sure). Results: Pilot study: All screening strategies had a 100% sensitivity, and the aPTT-ratio reached the highest specificity (82%; 95%CI: 74-90%). Within the evaluation study, following sensitivities for LA screening were observed: aPTT-SL 59.0% (95%CI: 57-61%), aPTT-LA 82.1% (95%CI: 80-84%), aPTT-ratio 92.3% (95%CI: 91-94), and LA-Check 83.3% (95%CI: 82-85%). Conclusion: Calculating a ratio between the LA-sensitive PTT-LA and the less sensitive Pathromtin-SL improves the performance of the PTT-LA itself and represents a simple and sensitive aPTT-based integrated strategy for LA screening.

Identification et analyse des éléments caractérisant la participation de la population locale et les paramètres à considérer pour l'élaboration d'un plan d'aménagement et de gestion de terroir: Cas du Fokontany Ambohibary Sokafana - Corridor Anjozorobe Angavo

La gestion durable des ressources naturelles est actuellement perçue comme une condition essentielle pour le développement durable, et surtout pour les pays en développement comme Madagascar. Face à la dégradation continue des ressources naturelles et surtout forestières, diverses stratégies sont adoptées par l’état malgache, dont l’extension des aires protégées qui veut allier la protection intégrale de certaines parties des ressources, et la satisfaction des besoins des populations riveraines. Le Code des Aires Protégées constitue un outil destiné à la gestion de ces aires de conservation. Toutefois, l’élaboration du plan d’aménagement ne prend pas souvent en compte des paramètres tels que l’augmentation de la population et les besoins qui s’en suivent, ou bien la participation de ces populations au processus d’élaboration et de mise en oeuvre du plan. Le défi est d’arriver à intégrer ces deux logiques de protection et de satisfaction des besoins de la population locale en réalisant des plans d’aménagement et de gestion concertés. Le cas du fokontany Ambohibary Sokafana dans le Corridor Anjozorobe Angavo est étudié pour identifier les paramètres à considérer si on veut atteindre cet objectif : paramètres écologiques et socio-économiques influençant la gestion des ressources forestières, critères permettant de définir la participation des acteurs dans cette gestion. Une revue des ouvrages spécifiques traitant du sujet ainsi que des observations et rencontres avec les divers acteurs sur terrain ont été menées afin de pouvoir identifier ces divers paramètres. Les analyses ont permis d’avancer deux scénarii qui traduisent l’intégration de la protection des forêts et la satisfaction des besoins en bois et en produits vivriers des populations riveraines, en tenant compte des motivations de ces dernières à participer au processus d’appropriation du plan d’aménagement et de gestion.