Testing the involvement of the prefrontal cortex in lucid dreaming: A tDCS study

Recent studies suggest that lucid dreaming (awareness of dreaming while dreaming) might be associated with increased brain activity over frontal regions during rapid eye movement (REM) sleep. By applying transcranial direct current stimulation (tDCS), we aimed to manipulate the activation of the dorsolateral prefrontal cortex (DLPFC) during REM sleep to induce lucid dreaming. Nineteen participants spent three consecutive nights in a sleep laboratory. On the second and third nights they randomly received either 1 mA tDCS for 10 min or sham stimulation during each REM period starting with the second one. According to the participants' self-ratings, tDCS over the DLPFC during REM sleep increased lucidity in dreams. The effects, however, were not strong and found only in frequent lucid dreamers. While this indicates some preliminary support for the involvement of the DLPFC in lucid dreaming, further research, controlling for indirect effects of stimulation and including other brain regions, is needed.

The phenomenology of lucid dreaming: An online survey.

In lucid dreams the dreamer is aware that he or she is dreaming. Although such dreams are not that uncommon, many aspects of lucid dream phenomenology are still unclear. An online survey was conducted to gather data about lucid dream origination, duration, active or passive participation in the dream, planned actions for lucid dreams, and other phenomenological aspects. Among the 684 respondents who filled out the questionnaire, there were 571 lucid dreamers (83.5%). According to their reports, lucid dreams most often originate spontaneously in adolescence. The average lucid dream duration is about 14 minutes. Lucid dreamers are likely to be active in their lucid dreams and plan to accomplish different actions (e.g., flying, talking with dream characters, or having sex), yet they are not always able to remember or successfully execute their intentions (most often because of awakening or hindrances in the dream environment). The frequency of lucid dream experience was the strongest predictor of lucid dream phenomenology, but some differences were also observed in relation to age, gender, or whether the person is a natural or self-trained lucid dreamer. The findings are discussed in light of lucid dream research, and suggestions for future studies are provided.

Lucid dreaming during NREM sleep: Two case reports

Lucid dreams – dreams in which the dreamer is aware that is dreaming – most frequently occur during REM sleep, yet there is some evidence suggesting that lucid dreaming can occur during NREM sleep as well. By conducting a sleep laboratory study on lucid dreams, we found two possible instances of lucidity during NREM sleep which are reported here. While lucid dreaming during NREM sleep seems to be much rarer and more difficult to achieve, it appears to be possible and is most likely to occur during N1 sleep, somewhat less likely during N2 sleep and yet to be observed during N3 sleep. Future studies should explore induction methods, underlying neural mechanisms and perceptual/dream content differences between REM and NREM lucid dreams. Furthermore, a consensus agreement is needed to define what is meant by lucid dreaming and create a vocabulary that is helpful in clarifying variable psychophysiological states that can support self-reflective awareness.

Meta-Awareness During Day and Night: The Relationship Between Mindfulness and Lucid Dreaming

The present study explored the relationship between lucidity in dreams (awareness of dreams while dreaming) and mindfulness during wakefulness, also considering meditation as a possible moderating variable. An online survey was completed by 528 respondents, of whom 386 (73.1%) had lucid dream experiences. The reported frequency of lucid dreams was found to be positively related to higher dispositional mindfulness in wakefulness. This relationship was only present in those participants who reported acquaintance with meditation. Regarding the dimensions of mindfulness, lucid dream frequency was more strongly associated with mindful presence rather than acceptance. The findings support the notion of an existing relationship between lucidity in dreams and mindfulness during wakefulness, yet it remains unclear whether the relationship is influenced by actual meditation practice or whether it reflects some natural predispositions. Future studies should examine the role of different meditation practices, investigate personality variables that might influence the relationship, and explore how different facets of mindfulness and lucidity interrelate.

Generation of long, fully modified, and serum-resistant oligonucleotides by rolling circle amplification

Rolling Circle Amplification (RCA) is an isothermal enzymatic method generating single-stranded DNA products consisting of concatemers containing multiple copies of the reverse complement of the circular template precursor. Little is known on the compatibility of modified nucleoside triphosphates (dN*TPs) with RCA, which would enable the synthesis of long, fully modified ssDNA sequences. Here, dNTPs modified at any position of the scaffold were shown to be compatible with rolling circle amplification, yielding long (>1 kb), and fully modified single-stranded DNA products. This methodology was applied for the generation of long, cytosine-rich synthetic mimics of telomeric DNA. The resulting modified oligo-nucleotides displayed an improved resistance to fetal bovine serum.

4D/3D reduction of dualities: mirrors on the circle

We engineer a brane picture for the reduction of Seiberg dualities from 4D to 3D, valid also in the presence of orientifold planes. We obtain effective 3D dualities on the circle by T-duality, geometrizing the non-perturbative superpotential which is an affine Toda potential. When reducing to pure 3D, we define a double-scaling limit which creates a sector of interacting singlets, giving a unified mechanism for the brane reduction of dualities.

The Circle: Die neue Kolonisierung des inneren Menschen

Mit Hilfe des zeitgenössischen Romans 'The Circle' von Dave Eggers werden Entgrenzungs- und Verdichtungstendenzen moderner subjektivierter Arbeit illustriert, die einen Zusammenhang mit Burnout- und Erschöpfungsdepressionsdiagnosen plausibilisieren. Angesichts der Uneindeutigkeit der empirischen Evidenz wird vorgeschlagen, die Problematik der modernen Gestalt der Erwerbsarbeit – vor allem für diejenigen am unteren Ende der jeweiligen Hierarchien – nicht nur anhand ihrer Krankheitsträchtigkeit, sondern mit Hilfe des Konzepts der Lebensformen und ihrer normativen Aufladung zu kritisieren: Massiv entgrenzte und verdichtete Arbeit erscheint dann als Bruch des 'Arbeitsversprechens', das sich mit Entstehung der Arbeitsgesellschaft im 19. Jh. herausgebildet hat.