17 resultados para Hepatie auto-imune

em BORIS: Bern Open Repository and Information System - Berna - Suiça


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Milk cortisol concentration was determined under routine management conditions on 4 farms with an auto-tandem milking parlor and 8 farms with 1 of 2 automatic milking systems (AMS). One of the AMS was a partially forced (AMSp) system, and the other was a free cow traffic (AMSf) system. Milk samples were collected for all the cows on a given farm (20 to 54 cows) for at least 1 d. Behavioral observations were made during the milking process for a subset of 16 to 20 cows per farm. Milk cortisol concentration was evaluated by milking system, time of day, behavior during milking, daily milk yield, and somatic cell count using linear mixed-effects models. Milk cortisol did not differ between systems (AMSp: 1.15 +/- 0.07; AMSf: 1.02 +/- 0.12; auto-tandem parlor: 1.01 +/- 0.16 nmol/L). Cortisol concentrations were lower in evening than in morning milkings (1.01 +/- 0.12 vs. 1.24 +/- 0.13 nmol/L). The daily periodicity of cortisol concentration was characterized by an early morning peak and a late afternoon elevation in AMSp. A bimodal pattern was not evident in AMSf. Finally, milk cortisol decreased by a factor of 0.915 in milking parlors, by 0.998 in AMSp, and increased by a factor of 1.161 in AMSf for each unit of ln(somatic cell count/1,000). We conclude that milking cows in milking parlors or AMS does not result in relevant stress differences as measured by milk cortisol concentrations. The biological relevance of the difference regarding the daily periodicity of milk cortisol concentrations observed between the AMSp and AMSf needs further investigation.

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OBJECTIVE: To describe an alternative method for the treatment of non-responsive self-mutilation injuries in three dogs after carpal/tarsal arthrodesis. STUDY DESIGN: Case series ANIMALS: Two dogs with carpal injury and one dog with tarsal injury treated by arthrodesis METHODS: All dogs developed self-mutilation injuries due to licking and/or chewing of the toes within 21-52 days of surgery. Clinical signs did not resolve within one week after conservative treatment with wound debridement and protective bandages. Following general anaesthesia, a deep horseshoe-shaped skin incision, including the subdermal tissue, was performed proximal to the self-mutilation injury transecting the sensory cutaneous afferent nerves. The skin incision was closed with simple interrupted sutures. RESULTS: All wounds healed without complication. Self-mutilation resolved completely within 24 hours after surgery in all dogs. No recurrence was observed (5 months to 3 years). CONCLUSION: Non-selective cutaneous sensory neurectomy may lead to resolution of self-mutilation following arthrodesis in dogs. CLINICAL RELEVANCE: Failure of conservative treatment in self-mutilation injuries often leads to toe or limb amputation as a last resort. The technique described in this case series is a simple procedure that should be considered prior to amputation. The outcome of this procedure in dogs self-multilating due to neurological or behavioral disturbances unrelated to carpal or tarsal arthrodesis is not known.

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Der Schweizer Tänzer und Choreograph Thomas Hauert und seine 1998 gegründeten Kompanie ZOO arbeiten seit Jahren mit Tanzimprovisation. Sie nutzen diese als choreographische Methode, als Mittel zur Bewegungsfindung während des Probenprozesses und als Kompositionsmittel während der Live-Aufführungen. In der Improvisation geht es immer um ein gemeinschaftliches Tun, um ein Miteinander, um Interaktion und gegenseitige Rücksichtnahme. In meinem Vortrag möchte ich diskutieren, inwiefern sich die Improvisation im Stück You’ve Changed (2010) dezidiert als kollaborative und gemeinschaftliche Praxis zeigt und wie hierin die Generierung eines interaktiv erzeugten Ereignisses evident wird. Um zu verdeutlichen, wie sich in diesem Tanzstück Gruppen bilden, wie Sozialität, Kollektivität und Gemeinschaft performativ hervorgebracht und verhandelt werden, benutze ich den Tierschwarm als Metapher und Denkfigur. Der Schwarm als performatives, dynamisches Gebilde, als Bewegungskollektiv von gleichberechtigten Teilnehmern, bietet sich als Erklärungsmodell an. Ähnlich wie der Tierschwarm wird auch die hier stattfindende Live-Improvisation durch Unvorhersehbarkeit, Performativität, Ephemeralität, Dynamik und kinästhetische Übertragungsbewegungen zwischen den einzelnen Mitgliedern charakterisiert. Ausgehend von Jean- Luc Nancys Schrift Singulär plural sein werden des Weiteren philosophische Überlegungen zur Gemeinschaft hergestellt und die Frage verhandelt, wie sich der Begriff der Singularität für die Betrachtung der ‚choreographierten Improvisation’ You’ve Changed fruchtbar machen lässt.

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Autoimmune hepatitis is a systemic disease, difficult to diagnose due the high variability of the clinical presentation and some non specific histological features. The recent identification of additional autoantibodies used as serological markers, as well as simplified diagnostic criteria should help the primary care physician to advance with the diagnostic process. These progresses are crucial as undiagnosed and therefore untreated autoimmune hepatitis has a poor prognosis, whereas immunosuppressive therapy leads to remission in a majority of cases.