106 resultados para decay scheme
Filtro por publicador
- Aberdeen University (1)
- Academic Research Repository at Institute of Developing Economies (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (6)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (4)
- Applied Math and Science Education Repository - Washington - USA (1)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (13)
- Archive of European Integration (96)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (10)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (45)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (106)
- Brock University, Canada (3)
- Bucknell University Digital Commons - Pensilvania - USA (1)
- CentAUR: Central Archive University of Reading - UK (141)
- Cochin University of Science & Technology (CUSAT), India (7)
- Coffee Science - Universidade Federal de Lavras (1)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (7)
- Consorci de Serveis Universitaris de Catalunya (CSUC), Spain (51)
- Dalarna University College Electronic Archive (1)
- Digital Commons - Michigan Tech (1)
- Digital Commons @ DU | University of Denver Research (1)
- Digital Peer Publishing (2)
- DigitalCommons - The University of Maine Research (2)
- DigitalCommons@The Texas Medical Center (8)
- DigitalCommons@University of Nebraska - Lincoln (5)
- Digitale Sammlungen - Goethe-Universität Frankfurt am Main (1)
- Diposit Digital de la UB - Universidade de Barcelona (9)
- Doria (National Library of Finland DSpace Services) - National Library of Finland, Finland (3)
- Institute of Public Health in Ireland, Ireland (27)
- Instituto Politécnico do Porto, Portugal (10)
- Iowa Publications Online (IPO) - State Library, State of Iowa (Iowa), United States (1)
- Lume - Repositório Digital da Universidade Federal do Rio Grande do Sul (1)
- Martin Luther Universitat Halle Wittenberg, Germany (2)
- Massachusetts Institute of Technology (2)
- Ministerio de Cultura, Spain (1)
- National Center for Biotechnology Information - NCBI (10)
- Publishing Network for Geoscientific & Environmental Data (11)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (4)
- Repositório digital da Fundação Getúlio Vargas - FGV (1)
- Repositório Digital da UNIVERSIDADE DA MADEIRA - Portugal (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (132)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (4)
- School of Medicine, Washington University, United States (1)
- Scielo Saúde Pública - SP (11)
- Scottish Institute for Research in Economics (SIRE) (SIRE), United Kingdom (2)
- Universidad Autónoma de Nuevo León, Mexico (1)
- Universidad de Alicante (5)
- Universidad del Rosario, Colombia (1)
- Universidad Politécnica de Madrid (28)
- Universidade de Lisboa - Repositório Aberto (1)
- Universidade do Minho (9)
- Universitat de Girona, Spain (3)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (5)
- Université de Lausanne, Switzerland (22)
- Université de Montréal, Canada (4)
- University of Connecticut - USA (1)
- University of Michigan (5)
- University of Queensland eSpace - Australia (19)
- University of Southampton, United Kingdom (6)
Resumo:
Nonsense-mediated mRNA decay (NMD) was originally coined to define a quality control mechanism that targets mRNAs with truncated open reading frames due to the presence of a premature termination codon. Meanwhile, it became clear that NMD has a much broader impact on gene expression and additional biological functions beyond quality control are continuously being discovered. We review here the current views regarding the molecular mechanisms of NMD, according to which NMD ensues on mRNAs that fail to terminate translation properly, and point out the gaps in our understanding. We further summarize the recent literature on an ever-rising spectrum of biological processes in which NMD appears to be involved, including homeostatic control of gene expression, development and differentiation, as well as viral defense.