16 resultados para Socio-educational approach
Filtro por publicador
- Repository Napier (3)
- Abertay Research Collections - Abertay University’s repository (1)
- Academic Research Repository at Institute of Developing Economies (2)
- Adam Mickiewicz University Repository (4)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (9)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (3)
- Aquatic Commons (7)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (2)
- Archive of European Integration (1)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (1)
- Aston University Research Archive (19)
- B-Digital - Universidade Fernando Pessoa - Portugal (1)
- Biblioteca de Teses e Dissertações da USP (1)
- Biblioteca Digital | Sistema Integrado de Documentación | UNCuyo - UNCUYO. UNIVERSIDAD NACIONAL DE CUYO. (2)
- Biblioteca Digital da Câmara dos Deputados (1)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (8)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (3)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (15)
- Bioline International (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (16)
- Brock University, Canada (16)
- Bucknell University Digital Commons - Pensilvania - USA (1)
- Bulgarian Digital Mathematics Library at IMI-BAS (2)
- CentAUR: Central Archive University of Reading - UK (18)
- Central European University - Research Support Scheme (1)
- Cochin University of Science & Technology (CUSAT), India (3)
- Collection Of Biostatistics Research Archive (1)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (9)
- CORA - Cork Open Research Archive - University College Cork - Ireland (3)
- Corvinus Research Archive - The institutional repository for the Corvinus University of Budapest (1)
- CUNY Academic Works (1)
- Dalarna University College Electronic Archive (5)
- Deakin Research Online - Australia (105)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (1)
- Digital Archives@Colby (1)
- Digital Commons - Michigan Tech (1)
- Digital Commons at Florida International University (11)
- Digital Peer Publishing (8)
- DigitalCommons@The Texas Medical Center (8)
- DRUM (Digital Repository at the University of Maryland) (1)
- Escola Superior de Educação de Paula Frassinetti (1)
- Fachlicher Dokumentenserver Paedagogik/Erziehungswissenschaften (1)
- FUNDAJ - Fundação Joaquim Nabuco (2)
- Glasgow Theses Service (3)
- Helda - Digital Repository of University of Helsinki (10)
- Illinois Digital Environment for Access to Learning and Scholarship Repository (2)
- Indian Institute of Science - Bangalore - Índia (1)
- Instituto de Engenharia Nuclear, Brazil - Carpe dIEN (1)
- Instituto Politécnico de Castelo Branco - Portugal (1)
- Instituto Politécnico de Leiria (1)
- Instituto Politécnico de Santarém (4)
- Instituto Politécnico de Viseu (6)
- Instituto Politécnico do Porto, Portugal (7)
- Memoria Académica - FaHCE, UNLP - Argentina (15)
- Ministerio de Cultura, Spain (5)
- Nottingham eTheses (1)
- Open University Netherlands (1)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (1)
- Portal de Revistas Científicas Complutenses - Espanha (9)
- Publishing Network for Geoscientific & Environmental Data (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (33)
- Queensland University of Technology - ePrints Archive (123)
- RDBU - Repositório Digital da Biblioteca da Unisinos (1)
- ReCiL - Repositório Científico Lusófona - Grupo Lusófona, Portugal (4)
- Repositório Aberto da Universidade Aberta de Portugal (1)
- REPOSITÓRIO ABERTO do Instituto Superior Miguel Torga - Portugal (2)
- Repositorio Académico de la Universidad Nacional de Costa Rica (6)
- Repositório Científico da Universidade de Évora - Portugal (2)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (31)
- Repositório Científico do Instituto Politécnico de Santarém - Portugal (3)
- Repositorio de la Universidad de Cuenca (1)
- Repositório digital da Fundação Getúlio Vargas - FGV (4)
- Repositório Institucional da Universidade de Aveiro - Portugal (9)
- Repositório Institucional da Universidade de Brasília (2)
- Repositório Institucional da Universidade Estadual de São Paulo - UNESP (1)
- Repositório Institucional da Universidade Federal do Rio Grande do Norte (2)
- Repositório Institucional da Universidade Tecnológica Federal do Paraná (RIUT) (1)
- Repositorio Institucional de la Universidad de Málaga (3)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (83)
- Research Open Access Repository of the University of East London. (3)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (2)
- SAPIENTIA - Universidade do Algarve - Portugal (3)
- School of Medicine, Washington University, United States (1)
- Scielo España (1)
- Universidad de Alicante (3)
- Universidad del Rosario, Colombia (15)
- Universidad Politécnica de Madrid (13)
- Universidade Complutense de Madrid (1)
- Universidade de Lisboa - Repositório Aberto (1)
- Universidade Federal de Uberlândia (1)
- Universidade Federal do Pará (11)
- Universidade Federal do Rio Grande do Norte (UFRN) (25)
- Universidade Metodista de São Paulo (11)
- Universita di Parma (1)
- Universitat de Girona, Spain (3)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (7)
- Université de Lausanne, Switzerland (2)
- Université de Montréal (3)
- Université de Montréal, Canada (28)
- University of Canberra Research Repository - Australia (1)
- University of Connecticut - USA (1)
- University of Michigan (4)
- University of Queensland eSpace - Australia (9)
- University of Washington (3)
- WestminsterResearch - UK (3)
- Worcester Research and Publications - Worcester Research and Publications - UK (5)
Resumo:
OBJECTIVE The repair of cartilaginous lesions within synovial joints is still an unresolved and weighty clinical problem. Although research activity in this area has been indefatigably sustained, no significant progress has been made during the past decade. The aim of this educational review is to heighten the awareness amongst students and scientists of the basic issues that must be tackled and resolved before we can hope to escape from the whirlpool of stagnation into which we have fallen: cartilage repair redivivus! DESIGN Articular-cartilage lesions may be induced traumatically (e.g., by sports injuries and occupational accidents) or pathologically during the course of a degenerative disease (e.g., osteoarthritis). This review addresses the biological basis of cartilage repair and surveys current trends in treatment strategies, focussing on those that are most widely adopted by orthopaedic surgeons [viz., abrasive chondroplasty, microfracturing/microdrilling, osteochondral grafting and autologous-chondrocyte implantation (ACI)]. Also described are current research activities in the field of cartilage-tissue engineering, which, as a therapeutic principle, holds more promise for success than any other experimental approach. RESULTS AND CONCLUSIONS Tissue engineering aims to reconstitute a tissue both structurally and functionally. This process can be conducted entirely in vitro, initially in vitro and then in vivo (in situ), or entirely in vivo. Three key constituents usually form the building blocks of such an approach: a matrix scaffold, cells, and signalling molecules. Of the proposed approaches, none have yet advanced beyond the phase of experimental development to the level of clinical induction. The hurdles that need to be surmounted for ultimate success are discussed.