222 resultados para scienza
Resumo:
Questo lavoro intende offrire una prima panoramica generale del carteggio di Ulisse Aldrovandi (1522-1605), contenuto prevalentemente presso il Fondo Aldrovandi della Biblioteca Universitaria di Bologna. Lo studioso di storia naturale bolognese aveva infatti scambiato oltre 2.100 lettere con corrispondenti provenienti da zone anche geograficamente remote. Del totale complessivo di queste lettere, solo poche sono state pubblicate, mentre una percentuale significativa di lettere rimane ancora oggi inedita. La presente ricerca non ha tuttavia come obiettivo l’edizione delle lettere, ma uno studio analitico delle funzioni e delle caratteristiche preminenti di questa corrispondenza esaminata nella sua totalità.
Resumo:
Using Computational Wind Engineering, CWE, for solving wind-related problems is still a challenging task today, mainly due to the high computational cost required to obtain trustworthy simulations. In particular, the Large Eddy Simulation, LES, has been widely used for evaluating wind loads on buildings. The present thesis assesses the capability of LES as a design tool for wind loading predictions through three cases. The first case is using LES for simulating the wind field around a ground-mounted rectangular prism in Atmospheric Boundary Layer (ABL) flow. The numerical results are validated with experimental results for seven wind attack angles, giving a global understanding of the model performance. The case with the worst model behaviour is investigated, including the spatial distribution of the pressure coefficients and their discrepancies with respect to experimental results. The effects of some numerical parameters are investigated for this case to understand their effectiveness in modifying the obtained numerical results. The second case is using LES for investigating the wind effects on a real high-rise building, aiming at validating the performance of LES as a design tool in practical applications. The numerical results are validated with the experimental results in terms of the distribution of the pressure statistics and the global forces. The mesh sensitivity and the computational cost are discussed. The third case is using LES for studying the wind effects on the new large-span roof over the Bologna stadium. The dynamic responses are analyzed and design envelopes for the structure are obtained. Although it is a numerical simulation before the traditional wind tunnel tests, i.e. the validation of the numerical results are not performed, the preliminary evaluations can effectively inform later investigations and provide the final design processes with deeper confidence regarding the absence of potentially unexpected behaviours.
Resumo:
This project aims to develop energy-saving methods for manufacturing tiles by using geopolymerization as an innovative processing technique. In fact, classical ceramic tiles are usually produced by sintering at temperatures ranging between 1100-1250 °C depending on natural raw materials selected for the mixture. Geopolymers, instead, are amorphous aluminosilicate inorganic polymers obtained by mixing alkali-silicate solutions with reactive aluminosilicate precursors, and geopolymerization may occur at room temperature or at temperature lower than 150 °C, and several types of waste may be used as geopolymer precursors. The possibility to obtain geopolymer tiles with properties comparable with those of ceramic tiles is extremely challenging, but geopolymerization would represent a huge energy-saving in the consolidation process as well as in natural raw materials exploitation.
Resumo:
The Mufarriḥ an-nafs (Soul-Cheerer), attributed to Badr ad-Dīn Muẓaffar Ibn Qāḍī Baʿlabakk, who served under the Ayyubids as the Chief Medical Officer of Damascus in the mid-13th century, was written as a comprehensive guide for physicians outlining different approaches to cheering the soul. The tractate is divided into ten chapters, which explore the nature of the soul, its distinction to the body as well as their connection through sensorial perception. Ibn Qāḍī Baʿlabakk distinguishes the bodily senses – hearing, vision, smell, taste, touch – and the inner senses, which he sees as stimulated through activities such as hunting and engagement in poetry and the sciences. The seventh chapter of the Mufarriḥ an-nafs includes an extended encyclopedia on materia medica as well as dispensatory of simple and compound drugs, which is devoted to treating the soul and remains unparalleled in the history of Islamicate medicine. My doctoral dissertation offers a complete recension and translation of the Mufarriḥ an-nafs based on a stemma codicum drawn from the seventeen extant text witnesses. The dissertation contextualizes the work, its author as well as sources, and features a text commentary that seeks to enable the reader to easily place and understand the Mufarriḥ an-nafs within the tradition of Galenic medicine. The glossaries on materia medica found at the end of the dissertation are aimed at facilitating access to the pharmacological dispensatory included in the seventh chapter.
Resumo:
La crisis existencial del proyecto de integración europea constituye el principal reto al que debe enfrentarse la Comunidad en su futuro más inmediato puesto que se alza como toda una amenaza para la continuidad del sistema establecido desde el Tratado fundacional de Roma (1957). Las tres crisis acontecidas durante los primeros años del siglo XXI, véase la gran crisis económica del año 2008, la pandemia global de la Covid-19 y la actual intervención de la Federación Rusa en Ucrania, están poniendo constantemente a prueba la firmeza de los cimientos y valores sobre los cuales se ha construido la Comunidad durante todos estos años. Esta tesis doctoral pretende ser una contribución académica al debate abierto en las sociedades comunitarias acerca de por donde debe de transitar la evolución del proyecto de integración europea en los próximos años. Para conseguir alcanzar este objetivo, la investigación se retrotrae hasta los orígenes del proceso de integración y avanza en la línea temporal hasta nuestros días, analizando con ello las posibles causas que pudieran encontrarse detrás de la crisis existencial actual. A su vez, , la investigación estudia con detenimiento los múltiples efectos que está generando la problemática existencial en los Estados miembros en los últimos años, tales como el aumento del apoyo social a favor de actores considerados populistas o el fenómeno de la creciente desafección ciudadana. Esta investigación analiza los distintos escenarios propuestos por la Comisión Europea en su Libro Blanco sobre el futuro de Europa para determinar cuál podría ser el mejor escenario que concordara con la nueva realidad económica y sociopolítica que actualmente impera en los Estados miembro. Lo que se persigue es formular una propuesta que pueda dar por terminada la crisis existencial de la Comunidad abriendo con ello una nueva etapa en la historia de la integración europea.
Resumo:
Recent scholarly works on the relationship between ‘fashion’ and ‘sustainability’ have identified a need for a systemic transition towards fashion media ‘for sustaianbility’. Nevertheless, the academic research on the topic is still limited and rather circumscribed to the analysis of marketing practices, while only recently some more systemic and critical analyses of the symbolic production of sustainability through fashion media have been undertaken. Responding to this need for an in-depth investigation of ‘sustainability’-related media production, my research focuses on the ‘fashion sustainability’-related discursive formations in the context of one of the most influential fashion magazines today – Vogue Italia. In order to investigate the ways in which the ‘sustainability’ discourse was formed and has evolved, the study considered the entire Vogue Italia archive from 1965 to 2021. The data collection was carried out in two phases, and the individualised relevant discursive units were then in-depth and critically analysed to allow for a grounded assessment of the media giant’s position. The Discourse-Historical Approach provided a methodological base for the analysis, which took into consideration the various levels of context: the immediate textual and intertextual, but also the broader socio-cultural context of the predominant, over-production oriented and capital-led fashion system. The findings led to a delineation of the evolution of the ‘fashion sustainability’ discourse, unveiling how despite Vogue Italia’s auto-determination as attentive to ‘sustainability’-related topics, the magazine is systemically employing discursive strategies which significantly mitigate the meaning of the ‘sustainable commitment’ and thus the meaning of ‘fashion sustainability’.
Resumo:
This research addresses the use of ex ante contracts to arbitrate tort claims in domestic settings using law and economics research methodologies. Potential economic benefits from using arbitration, particularly between informed and knowledgeable parties and in international business transactions, are not guaranteed in domestic disputes. Arbitration can potentially be used to manipulate the adjudication process. This research has several findings. There is a lack of information available concerning the use of arbitration to adjudicate tort claims. Proxy measurements concerning the demand for third party adjudication and other legal indicators are a poor substitute for the information hidden behind the veil of arbitration. There is the potential for the strategic use of ex ante contracts to arbitrate tort claims by repeat player tortfeasors to domestic tort claims, both individually and in concert with other repeat player firms. These strategic efforts aim to: manipulate enforcement errors for tort claims, avoid procedural rules which have the effect of lowering enforcement errors, enable a unique type of domestic forum arbitrage, shirk from taking due care, capture the economic benefit of using arbitration, manipulate the stock of precedents and production of public goods from courts, collude in these underlying efforts, restrain competition, indirectly fix prices, and other aims which increase the repeat player tortfeasor’s or their industries economic gains related to their underlying contracts and tort disputes. This research also demonstrates how this subject is appropriate for further academic research and why states should be cautious of giving carte blanche to arbitrate all domestic tort claims.
Resumo:
Total hip and knee replacements (THR/TKR) are considered the gold standard surgical treatments for end-stage osteoarthritis (OA), effectively alleviating pain, enhancing joint mobility and quality of life (QoL). Maintaining an active lifestyle and regular physical activity (PA) is crucial for these patients, as it can increase bone density and stability of joint prosthesis. This thesis aims to: (1) systematically review recommendations from healthcare professionals; (2) explore interventions promoting an active lifestyle post-THR and TKR; (3) investigate the primary causes of stiffness post-TKR; (4) design an exercise protocol to enhance QoL post-THR and TKR; (5) evaluate orthopedic surgeons' attitudes toward PA for patients post-THR/TKR; and (6) assess changes in QoL after a specifically designed PA intervention. The initial review revealed consensus on permissible sports activities post-surgery, but few studies addressed interventions targeting PA behaviors. Subsequently, findings highlighted key factors contributing to post-TKR stiffness, including mispositioned components, psychological distress, and obesity. Building on these insights, a PA intervention was implemented, followed by a survey investigating orthopedic surgeons' attitudes towards PA, which demonstrated a general positive attitude. Lastly, a pilot randomized controlled trial demonstrated significant enhancements in QoL, physical function, and clinical outcomes following a three-month adapted PA intervention. Future research should focus on raising awareness among individuals and healthcare professionals, fostering engagement in PA programs, and promoting active lifestyles. PA represents a valuable strategy for mitigating the burden of chronic diseases on society.
Resumo:
The integration of quantitative data from movement analysis technologies is reshaping the analysis of athletes’ performances and injury mitigation, e.g., anterior cruciate ligament (ACL) rupture. Most of the movement assessments are performed in laboratory environments. Recent progress provides the chance to shift the paradigm to a more ecological approach with sport-specific elements and a closer examination of “real” movement patterns associated with performance and (ACL) injury risk. The present PhD thesis aimed at investigating the on-field motion patterns related to performance and injury prevention in young football players. The objectives of the thesis were: (I) in-lab measures of high-dynamics movements were used to validate wearable inertial sensors technology; (II) in-laboratory and on-field agility movement tasks were compared to inspect the effect of football-specific environment; (III) on-field analysis was conducted to challenge wearable sensors technology in the assessment of dangerous movement patterns towards the ACL rupture; (IV) an overview of technologies that could shape present and future assessment of ACL injury risk in daily practice was presented. The validity of wearables in the assessment of high-dynamics movements was confirmed. Relevant differences emerged between the movements performed in a laboratory setting and on the football pitch, supporting the inclusion of an ecological dynamics approach in preventive protocols. The on-field analysis of football-specific movement tasks demonstrated good reliability of wearable sensors and the presence of residual dangerous patterns in the injured players. A tool to inspect at-risk movement patterns on the field through objective measurements was presented. It discussed how potential alternatives to wearable inertial sensors embrace artificial intelligence and closer collaboration between clinical and technical expertise. The present thesis was meant to contribute to setting the basis for data-driven prevention protocols. A deeper comprehension of injury-related principles and counteractions will contribute to preserving athletes’ careers and health over time.
Resumo:
Ziel dieser Dissertation ist es, die grundlegenden philosophisch-theoretischen Implikationen von Schellings letzter systematischer Darlegung seiner Naturphilosophie nach dem Berliner Textfragment von 1843/44, der “Darstellung des Naturprocesses”, zu untersuchen. Angesichts der sich zwischen den 1830 und den 1860 Jahren in Berlin abzeichnenden neuen intellektuellen Tendenzen und der Entwicklungen in den Naturwissenschaften legt Schelling hier die Grundlagen für eine allgemeine Ontologie des Wirklichen in kritischer Auseinandersetzung mit Kants transzendentalem Idealismus. Innerhalb des systematischen Horizonts der "apriorischen Vernunftwissenschaft" oder "negativen Philosophie" stellt er im ersten Teil seines Werkes die Prinzipien fest, die die „Idee des Existierenden“ ausmachen, und beschreibt die rationale Operation, die durchgeführt werden muss, um zum Gedanken einer „Welt außer der Idee“ zu gelangen. Die philosophisch-systematischen Annahmen, die mit dem Übergang von der bloßen Idee des Existierenden zum Gedanken der außeridealen Welt verbunden sind, werden im ersten Kapitel dieser Dissertation untersucht. Im zweiten Teil seines Werkes definiert Schelling durch eine detaillierte Analyse von Kants Transzendentalen Ästhetik den Raum als diejenige Form, in der uns die Existenzen als voneinander getrennt vorstellen lassen. Obwohl der Zeitbegriff von Schelling nur am Rande behandelt wird, trägt er zusammen mit dem Raum dazu bei, die erste ontologische Grundstruktur der außeridealen Welt zu definieren. Die Analyse von Schellings Konzeption der raumzeitlichen Grundstruktur der außeridealen Welt stellt das Thema des zweiten Kapitels dieser Dissertation dar. Schließlich bestimmt Schelling im dritten Teil seines Werkes die Finalität als diejenige Kausalitätsform, die es ermöglicht, die außerideale Welt als einen werdenden Kontext zu verstehen, dessen Entwicklungsstufen die siderische Welt, die unorganische Welt und die organische Welt sind. Die Schelling‘sche Definition der Teleologie der Natur als zweite ontologische Grundstruktur der außeridealen Welt ist das Thema des dritten Kapitels dieser Dissertation.
Resumo:
As the word population continues to grow and global resources are limited, the WHO definition of health is difficult to achieve for a large part of the population. Humanity is facing the need to improve both environmental and human wellbeing. This can be done through careful planning and management of natural resources, ensuring food safety and reducing and converting wastes. This work aims to contribute to the improvement of population and environmental health exploring different research fields: urban park ecosystem services, food chemical risk assessment and agri-food by-product valorization. To highlight the importance of urban parks and their ecosystem services, an ethnobotanical study was carried out in the Ausa urban park in Rimini, using a citizen science approach. The results showed that Ausa Park is an important focal point for plant gatherers in Rimini, as it allows for plant foraging and contributes to preserve the knowledge of the use of plants. Two food safety studies were carried out, looking at the exposure of Poles to bisphenol A through the consumption of soft drinks and to cadmium through the consumption of chocolate bars. The results, compared with EFSA’s scientific opinion, show that the exposure of the Polish population to BPA is of health concern, while cadmium is not. In the agri-food by-product valorization, a green extraction method was optimized to recover valuable phenolic compounds from red-fleshed apple pomace; moreover, the possibility of recovering pectin from the residue was evaluated. Furthermore, valuable compounds in four different types of wheat milling by-products, considered as an alternative source of bioactive compounds with potential human health benefits, were investigated. In conclusion, this work produced usable data in urban green area management and planning, in food chemical risk assessment and in business production decisions, thus contributing to improving environmental and people wellbeing.
Transatlantic regulatory divergence in pharmaceuticals: exploring economic and cultural explanations
Resumo:
The analysis delves into the regulatory divergence between the EU and the US in the pharmaceutical sector. Through law and economics, political science, and cultural theory perspectives, the study explores how collective preferences within each jurisdiction shape regulations. By identifying cultural orientations such as individualism in the US and hierarchy in the EU, the research suggests that underlying cultural factors play a significant role in regulatory decisions. Despite calls for regulatory harmonization, the recognition of legitimate differences in preferences due to cultural diversity emphasizes that uniformity may not always be the best solution, showcasing the importance of understanding cultural influences in shaping regulatory landscapes.