A informação social no corpo travesti (Belém, Pará): uma análise sob a perspectiva de Erving Goffman

Inspiradas em um ideal de mulher, as travestis investem em uma morfologia híbrida, combinando signos de masculinidade e feminilidade, que acabam por desqualificá-las para a sociedade maior. Partindo da noção de informação social de Goffman, este trabalho tem por objetivo fazer uma leitura dos corpos dos sujeitos em questão, o que se dá sob uma perspectiva relacional. O corpus submetido à análise constitui-se do material obtido de pesquisa etnográfica realizada em 2002 e 2003 entre as travestis que se prostituem em Belém, Pará. De modo geral, os corpos das travestis comunicam uma diversidade de informações, as quais falam sobre estigma, desvio, violência e desejo na capital paraense.

GABA and glutamate transporters: new events and function in the vertebrate retina

The neural retina is a highly complex tissue composed of excitatory and inhibitory neurons and glial cells. Glutamate, the main excitatory neurotransmitter, mediates information transfer from photoreceptors, bipolar cells, and ganglion cells, whereas interneurons, mainly amacrine and horizontal cells, use γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter. In this review we place an emphasis on glutamate and GABA transporters as highly regulated molecules that play fundamental roles in neurotransmitter clearance, neurotransmitter release, and oxidative stress. We pharmacologically characterized glutamate transporters in chicken retina cells and identified two glutamate transporters: one Na+-dependent transporter and one Na+-independent transporter. The Na+-dependent uptake system presented characteristics related to the high-affinity xAG- system (EAAT1), and the Na+-independent uptake system presented characteristics related to the xCG- system, which highly contributes to glutamate transport in the retina. Glutamate shares the xCG- system with another amino acid, L-cysteine, suggesting the possible involvement of glutathione. Both transporter proteins are present mainly in Müller glial cells. GABA transporters (GATs) mediate high-affinity GABA uptake from the extracellular space and terminate the synaptic action of GABA in the central nervous system. GABA transporters can be modulated by molecules that act on specific sites to promote transporter phosphorylation and dephosphorylation. In addition to a role in the clearance of GABA, GATs may also release GABA through a reverse transport mechanism. In the chicken retina, a GAT-1 blocker, but not GAT2/3 blocker, was shown to inhibit GABA uptake, suggesting that GABA release from retina cells is mainly mediated by a GAT-1-like transporter.