2 resultados para Dependent Failures, Interactive Failures, Interactive Coefficients, Reliability, Complex System
em Universidade Federal do Pará
Resumo:
Esta pesquisa investiga a inserção de pessoas com deficiência visual no mercado de trabalho, focalizando empresas privadas da Região Metropolitana de Belém no período de 2000 a 2006. O mercado de trabalho é compreendido, neste estudo, como um complexo sistema, resultante das regras predominantes da relação capital e trabalho, porém paralelamente, há mecanismos de inserção ancorados em critérios, nem sempre explícitos, que podem produzir resultados discriminatórios. A pesquisa teve como principal fonte, informações obtidas junto a empresas privadas da Região Metropolitana de Belém. Observa-se nesse período, uma tímida inserção das pessoas com deficiência visual no mercado de trabalho, assim como uma significativa disparidade entre a inserção de pessoas com baixa visão e a das cegas, sendo a presença destas, quase inexistente em empresas privadas da Região Metropolitana de Belém.
Resumo:
In order to determine the modulation of anxiolytic and panicolytic-like effects of diazepam by the hormonal cycle of female rats, male and female rats – the latter divided per estrous cycle phase (estrus, diestrus, metaestrus and proestrus) – were tested in the elevated T-maze, a behavioral model of panic and anxiety. Diazepam (0.5, 1.0 and 2.0 mg/kg) or saline solution was injected in individual animals that were submitted to one session in the elevated T-maze 25 min after drug/saline administration. The test consisted of three avoidance trials and one escape trial, separated by a 30 s interval, during which the animals were isolated in individual cages. The avoidance trials began with the animal being placed at the end of the maze's enclosed arm. The time necessary for the animal to leave the central square was considered as the response's latency. The trials that exceeded 300 s were considered as failures. Results demonstrate a decrease in the effects of diazepam in inhibitory avoidance (anxiety) trials in females in diestrus and proestrus, but no relation of gender or estrous cycle on diazepam effects on escape trials (fear). The results support the hypothesis that down-regulation of GABAA receptors by activation of nuclear estrogen receptors and induction of PKC-mediated GABAA receptor phosphorylation by activation of surface estrogen receptors in raphe neurons underlie the modulation of diazepam sensitivity by estrogen.