Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil

The presence of human papillomavirus (HPV) was evaluated in 65 samples of prostate tumours and six samples of prostates with benign prostatic hyperplasia from individuals from Northern Brazil. We used a highly sensitive test, the Linear Array HPV Genotyping Test, to detect 37 high and low-risk HPV types. In this study, only 3% of tumour samples showed HPV infection. Our findings support the conclusion that, despite the high incidence of HPV infection in the geographic regions studied, HPV was not associated with a higher risk of prostate cancer. To our knowledge, this is the first study evaluating the frequency of HPV detection in prostatic tissue of individuals from Brazil.

Mitochondrial DNA mapping of social-biological interactions in Brazilian Amazonian African-descendant populations

ABSTRACT: The formation of the Brazilian Amazonian population has historically involved three main ethnic groups, Amerindian, African and European. This has resulted in genetic investigations having been carried out using classical polymorphisms and molecular markers. To better understand the genetic variability and the micro-evolutionary processes acting in human groups in the Brazilian Amazon region we used mitochondrial DNA to investigate 159 maternally unrelated individuals from five Amazonian African-descendant communities. The mitochondrial lineage distribution indicated a contribution of 50.2% from Africans (L0, L1, L2, and L3), 46.6% from Amerindians (haplogroups A, B, C and D) and a small European contribution of 1.3%. These results indicated high genetic diversity in the Amerindian and African lineage groups, suggesting that the Brazilian Amazonian African-descendant populations reflect a possible population amalgamation of Amerindian women from different Amazonian indigenous tribes and African women from different geographic regions of Africa who had been brought to Brazil as slaves. The present study partially mapped the historical biological and social interactions that had occurred during the formation and expansion of Amazonian African-descendant communities.

Dinheiro no Brasil: um estudo comparativo do significado do dinheiro entre as regiões geográficas brasileiras

Este estudo comparou o significado do dinheiro predominante nas regiões brasileiras usando a Escala de Significado do Dinheiro (ESD), composta pelos componentes Desigualdade, Progresso, Cultura, Poder, Desapego, Conflito, Estabilidade, Sofrimento e Prazer. O estudo foi conduzido com amostra de 760 sujeitos, 60% mulheres, com idades, ocupações e renda variadas, e mais de cinco anos de residência no local. Os resultados indicaram diferenças significativas em todos os componentes, exceto Prazer e Sofrimento, e padrões diferenciados: maior Estabilidade no Norte, maior Conflito e Desapego no Nordeste, menor Estabilidade e Poder no Distrito Federal, menor Conflito e Poder no Sul, e no Sudeste, maior Poder, Desigualdade, Cultura, Prazer e Sofrimento e menor Desapego. Exame separado da região Sudeste indicou maior diversidade interna do que entre as regiões do país. Estes resultados são discutidos a partir de diferenças histórico-culturais e estereótipos, indicando a sensibilidade da ESD para discriminar perfis de significado do dinheiro.