85 resultados para Trombose dos seios intracranianos


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Pós-graduação em Odontologia - FOA

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Medicina Veterinária - FMVZ

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Os anti-inflamatórios não esteroidais (AINEs) estão entre os medicamentos mais prescritos em todo o mundo, tanto na medicina humana, como na medicina veterinária. Atualmente os AINEs são classificados em não seletivos (convencionais ou clássicos), que são os mais antigos, e seletivos para COX-2 ou coxibes. Alguns estudos constataram uma possível relação entre os inibidores COX-2 seletivos e os efeitos adversos no sistema cardiovascular. Devido a isso, objetivou-se realizar um levantamento de pesquisas que comprovem os efeitos cardiovasculares ocasionados por essa classe farmacológica utilizando livros e artigos das bases de dados PubMed, Periódicos da Capes e SciELO que respondessem à pergunta: a inibição da COX-2 acarreta efeitos adversos para o sistema cardiovascular?. Do total de resultados encontrados, foram utilizados 16 artigos. Os trabalhos mostraram que o uso de inibidores da COX-2 alterou o perfil de coagulação para uma tendência trombótica, além de diminuir a resposta vasodilatadora gerada na resposta inflamatória. Diante dos resultados obtidos através desses estudos, conclui-se que a COX-2 desempenha papel fisiológico no sistema cardiovascular, facilitando a não formação de trombos nos vasos sanguíneos, e, portanto, que sua inibição favorece a coagulação. Assim, os fármacos que inibem a COX-2 devem ser prescritos com cautela, levando-se em consideração o perfil de coagulação do paciente

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Pós-graduação em Bases Gerais da Cirurgia - FMB

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The oral anticoagulants (AOC) and platelet antiagregants are drugs used for the prevention of thromboembolic phenomena, such as pulmonary embolism in patients with atrial fribrilation heart valves, thrombosis and pulmonary embolism. For patients who are undergoing surgical procedures-dentistry were asked to discontinue the use of anticoagulants until the value of the INR remained = 2.0, that in order to avoid trans and hemorrhages in the postoperative period. However, the AOC can cause the formation of a clot, leading to obstruction of blood pathways. Thus, it became doubtful the medicine for surgery, in which local hemostatic measures would be sufficient to promote hemostasis. Thus, the objective of the review was to evaluate the risk of bleeding in patients AOC users that are subjected to surgical procedures, through a bibliographical survey carried out in relevant clinical studies published between 1990 and 2012, by the MedlinePubMed data. In this review of literature was concluded that the benefit of thromboembolism prevention overcomes the risk hemorrhage, therefore, it is recommended to keep the dose of anticoagulant therapy unchanged for patients undergoing oral surgery and implant dentistry, using appropriate INR levels with the assistance of local hemostatic. In addition, a refined surgical technique should be performed in these patients. With respect to the most invasive oral surgery, with a risk of bleeding, treatment may be necessary in conjunction with the medical staff.

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Few studies has been done using guided bone regeneration in maxillary sinus defects. AIM: To assess the bone repair process in surgical defects on the alveolar wall of the monkey maxillary sinus, which communicates with the sinus cavity, by using collagen membranes: Gen-derm - Genius Baumer, Pro-tape - Proline and autologous temporal fascia. MATERIALS AND METHODS: In this prospective and experimental study, orosinusal communications were performed in four tufted capuchin monkeys (Cebus apella) and histologic analysis was carried out 180 days after. RESULTS: In the defects without a cover (control), bone proliferation predominated in two animals and fibrous connective tissue predominated in the other two. In defects repaired with a temporal fascia flap, fibrous connective tissue predominated in three animals and bone proliferation predominated in one. In the defects repaired with Gen-derm or Pro-tape collagen membranes there was complete bone proliferation in three animals and fibrous connective tissue in one. CONCLUSIONS: Surgical defect can be repaired with both bone tissue and fibrous connective tissue in all study groups; collagen membranes was more beneficial in the bone repair process than temporal fascia or absence of a barrier.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Intracranial neoplasms are common causes of neurological disorders in middle-aged and elderly dogs. With the feasibility of computed tomography, it is now possible to determine the extent and exact location of brain tumors, identifying them ante mortem in dogs and cats. This paper aims to report the occurrence of a mixed glioma in a Boxer dog examined at the Veterinary Hospital of Unesp, Botucatu Campus. The animal presented with a brain syndrome of acute onset and progressive course. CT scan showed the presence of a mass in the right cerebral hemisphere extending from the frontal to the parietal region and involving the basal ganglia. Given the gravity of the neurological disorder, the owner chose to perform euthanasia. Microscopic analysis of the mass allowed the diagnosis of mixed glioma.