Técnicas cartográficas aplicadas ao zoneamento ambiental: município de Jacareí - SP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Zoneamento geoambiental da área urbana do município de Cubatão - SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O desenho e a trilha interpretativa como instrumentos de percepção e interpretação da paisagem urbana no ensino de Geografia

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influência da construção da usina hidroelétrica de Porto Primavera na evolução de canais de primeira ordem da rede de drenagem do Ribeirão das Anhumas - UGRHI Pontal do Paranapanema

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O clima urbano de Cândido Mota: análise do perfil térmico e higrométrico em episódios de verão

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

O zoneamento ecológico-econômico como instrumento de planejamento e gestão ambiental: uma proposta para a bacia hidrográfica do Rio Corumbataí (SP)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Gerenciamento de recursos hídricos subterrâneos: uso atual e potencial do sistema aquífero Guarani no estado de São Paulo (SP)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Determinações estratégicas e econômicas da dominação britânica no Egito (1804-1956)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise-multitemporal da paisagem, potecialidades e fragilidades sob a ótica do uso e ocupação: destaque para as terras da Alta Bacia do Rio Taboco-MS

Pós-graduação em Geografia - IGCE

Analysis of systemic inflammatory response in the carcinogenic process of uterine cervical neoplasia

The inflammatory response is an active process in cervical cancer and may act in the progression and/or regression of the lesion. At the site of inflammation, macrophages and neutrophils are present as well as cytokines such as TNF-alpha and IFN-gamma. This study aims to evaluate the inflammatory response levels in women with cervical intraepithelial lesions (CIN) and with squamous cell carcinoma (SCC) of the cervix. Serum samples obtained from women without evidence of disease (n = 30), with CIN (n = 30) and with SCC of the cervix (n = 30) were analyzed for the activities of N-acetylglucosaminidase (NAG) and myeloperoxidase (MPO) by enzymatic assay and the serum levels of TNF-alpha and IFN-gamma by ELISA assay. The activities of NAG and MPO and the level of TNF-alpha were higher in women with CIN compared to the women with SCC. The levels of IFN-gamma were lower in the group of women with CIN compared to the group with SCC. There was not a significant association between the degree of the CIN and the staging of the SCC of the cervix and the degree of inflammation as assessed by the levels of inflammatory markers. The inflammatory response was inversely correlated with the progression of the carcinogenic process. In the three groups, the control group, women with CIN and women with invasive SCC, there was no association between the degree of preinvasive lesions and staging of the SCC of the cervix. (C) 2011 Elsevier Masson SAS. All rights reserved.

Molecular mapping of the viral determinants of systemic wilting induced by a Lettuce mosaic virus (LMV) isolate in some lettuce cultivars

The isolate AF199 of Lettuce mosaic virus (LMV, genus Potyvirus) causes local lesions followed by systemic wilting and plant death in the lettuce cultivars Ithaca and Vanguard 75. Analysis of the phenotype of virus chimeras revealed that a region within the PI protein coding region (nucleotides 112-386 in the viral genome) and/or another one within the CI protein coding region (nucleoticles 5496-5855) are sufficient together to cause the lethal wilting in Ithaca, but not in Vanguard 75. This indicates that the determinants of this particular symptom are different in these two lettuce cultivars. The wilting phenotype was not directly correlated with differences in the deduced amino acid sequence of these two regions. Furthermore, transient expression of the LMV-AF 199 proteins, separately or in combination, did not induce local necrosis or any other visible reaction in the plants. Together, these results Suggest that the systemic wilting reaction might be Clue to RNA rather than protein sequences. (c) 2004 Elsevier B.V. All rights reserved.

Differential gene expression analysis of Paracoccidioides brasiliensis during keratinocyte infection

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Anthropometric midarm measurements can detect systemic fat-free mass depletion in patients with chronic obstructive pulmonary disease

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Retrospective analysis of post-exposure to human anti-rabies treatment in Botucatu, São Paulo State, Brazil

This analysis aimed to identify characteristics of accidents that would, probably, provoke rabies infection. A total of 14,409 survey questionnaires for surveillance of human rabies from the Brazilian Information System for Disease Notification (SINAN), from 2000 to 2005, were analyzed. Regarding demographics, it was observed that 7,377 (51.5%) of the victims were white, 4,458 (30.93%) were children and 8,008 (55.58%) were males. Urban cases were prevalent (88.10%) while dogs were the animals most frequently involved in accidents, in 11,700 cases (81.19%). Bites (84.35%) and scratches (19.15%) were the most prevalent exposure types, and occurred predominantly on victims' extremities (38.79%). The prophylactic measure taken in 6,179 cases comprised anti-rabies vaccine; of these victims, 421 (2.92%) showed systemic reactions while 693 (4.80%) reported no response. The importance of developing awareness in professionals that should correctly report post-exposure immunoprophylaxis cases is emphasized given the high number of individuals who receive this type of treatment annually.