61 resultados para production structure

em Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho"


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The effects of isolated compounds from Brazilian lichens and their derivatives on H 2O 2 and NO production were studied using murine macrophages as a part of an attempt to understand their possible immunomodulatory properties. The compound cytotoxicity was studied using MTT assay. Macrophage stimulation was evaluated by the determination of NO (Griess assay) and H 2O 2 (horseradish peroxidase/phenol red) in supernatants of peritoneal macrophage cultures of Swiss mice. This research demonstrated stimulatory activities of some phenolic compounds isolated from lichens and their derivatives on H 2O 2 and NO production. Structure-activity relationships suggest several synthetic directions for further improvement of immunological activity.

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Utilizando resultados de trabalho estatístico com base nos dados da Relação Anual de Informações Sociais (RAIS), que permitem caracterizar a indústria de calçados de Nova Serrana (MG) como um sistema local de produção, e nos resultados de pesquisa de campo efetuada em abril de 2002, quando foram realizadas entrevistas e visitas em empresas e instituições locais, o artigo estuda o sistema local de produção de Nova Serrana tanto em termos do sistema como um todo quanto das empresas e instituições que o compõem. O objetivo é produzir, nesses dois níveis de análise, evidências que possam orientar ações públicas e privadas, visando ao aprimoramento do sistema e das empresas locais em duas esferas: (1) produtiva e tecnológica, em seus vários desdobramentos, e (2) institucional e organizacional. Para isso, caracteriza e dimensiona primeiramente o sistema local em termos de sua localização e região de influência, sua logística, população e empregos gerados, história e evolução, estrutura de produção, instituições de apoio, contexto social, cultural e político. em seguida, caracteriza as empresas em termos de tamanho e quanto a: desenvolvimento de produto, sistemas de comercialização, relações cooperativas, interações com fornecedores, fontes de informação para desenvolvimento de produtos e sobre mercados e processos de fabricação, práticas e políticas quanto à qualidade, ao financiamento e a outros aspectos pertinentes ao caso em estudo. Por fim, ressalta os problemas mais relevantes que podem ser objeto de políticas públicas e/ou de ações conjuntas das empresas e instituições locais.

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Pós-graduação em Economia - FCLAR

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Pós-graduação em Agronomia (Energia na Agricultura) - FCA

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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The presented text aims to evaluate the causes that led to the formation of the current agrarian structure in Paraguay, Argentina and Uruguay as well as the characteristics of the agro-export model that takes place in these countries, which is based on production and export of soybeans. Because of its contemporary importance and represent the bulk of agricultural production in the countries under study, is established the objective of identifying the particularities and commonalities between these soybean production, with regard to its production structure and the benefits and impacts generated by this. Finally, statistical historical data are presented, enabling this comparison, showing the development and crucial moments for the establishment of the current standard

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This work aims to evaluate the different trajectories in terms of production structure, technological capabilities and performance in international trade of pharmaceutical industries in Brazil and India. For this, we build international trade indicators, based on data provided by the COMTRADE, the UN database for trade. Through the indicators, it is observed that the countries have different results in the catch-up process of the pharmaceutical industry. India has built a productive structure strongly based on generic drugs, with which it is able to greatly meet domestic demand and export to many countries worldwide. Brazil remains in a position of dependence of foreign production, with a high level of imports and exports to the region of Latin America

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Pós-graduação em Engenharia de Produção - FEB

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Currently, there is worldwide interest in the technological use of agro-industrial residues as a renewable source of food and biofuels. Lignocellulosic materials (LCMs) are a rich source of cellulose and hemicellulose. Hemicellulose is rich in xylan, a polysaccharide used to develop technology for producing alcohol, xylose, xylitol and xylo-oligosaccharides (XOSs). The XOSs are unusual oligosaccharides whose main constituent is xylose linked by β 1-4 bonds. The XOS applications described in this paper highlight that they are considered soluble dietary fibers that have prebiotic activity, favoring the improvement of bowel functions and immune function and having antimicrobial and other health benefits. These effects open a new perspective on potential applications for animal production and human consumption. The raw materials that are rich in hemicellulose include sugar cane bagasse, corncobs, rice husks, olive pits, barley straw, tobacco stalk, cotton stalk, sunflower stalk and wheat straw. The XOS-yielding treatments that have been studied include acid hydrolysis, alkaline hydrolysis, auto-hydrolysis and enzymatic hydrolysis, but the breaking of bonds present in these compounds is relatively difficult and costly, thus limiting the production of XOS. To obviate this limitation, a thorough evaluation of the most convenient methods and the opportunities for innovation in this area is needed. Another challenge is the screening and taxonomy of microorganisms that produce the xylanolytic complex and enzymes and reaction mechanisms involved. Among the standing out microorganisms involved in lignocellulose degradation are Trichoderma harzianum, Cellulosimicrobium cellulans, Penicillium janczewskii, Penicillium echinulatu, Trichoderma reesei and Aspergillus awamori. The enzyme complex predominantly comprises endoxylanase and enzymes that remove hemicellulose side groups such as the acetyl group. The complex has low β-xylosidase activities because β-xylosidase stimulates the production of xylose instead of XOS; xylose, in turn, inhibits the enzymes that produce XOS. The enzymatic conversion of xylan in XOS is the preferred route for the food industries because of problems associated with chemical technologies (e.g., acid hydrolysis) due to the release of toxic and undesired products, such as furfural. The improvement of the bioprocess for XOS production and its benefits for several applications are discussed in this study. © 2012 Elsevier Ltd.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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This paper is the result of the Masters dissertation studying the role and history of scientific communication, especially the changes that have occurred after the appearance of electronic communication and computer networks. This study showed that hypertext systems are increasingly being used in the scientific and academic world in the production of electronic journals; this makes it possible for the user to rapidly access information in their area. However, these systems need to be improved to help the user during search and access to information. Both printed journals migrating to electronic media, and the exclusively electronic journals should present the current quality indicators. The attempt was made to discover whether characteristics related to printed journals are being maintained in their electronic counterparts. For this, a prototype model was developed to analyze the structure of electronic scientific journals; it composes 14 criteria expressing aspects of quality for these journals. It includes elements of Website Information Architecture and those already in place in printed scientific journals in order to ensure that basic functions - archiving and dissemination - are maintained in electronic publishing. Each criterion consists of variables, which measure the maintenance of these functions both in the migrating printed journals and the exclusively electronic ones. This prototype model was used to analyze Ciência da Informação On-line and DataGramaZero - Revista de Ciência da Informação. Results indicate that this model is able to find out if the basic functions of archiving and dissemination are being maintained in electronic journals. Therefore, its implementation is justified in electronic journals. The model can help librarians, authors, and users of electronic journals to identify quality journals, and assist editors in developing their projects. The material from the study may be included in the preservice and inservice education of Information Science professionals and to support editors of scientific journals.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)