Estudo prospectivo observacional sobre a incidência de injúria renal aguda em unidade de terapia intensiva de um hospital universitário

OBJETIVO: Analisar comparativamente características clínicas e evolução de pacientes com e sem IRA adquirida em UTI geral de um hospital universitário terciário. MÉTODO: Estudo prospectivo observacional com 263 pacientes acompanhados diariamente durante a internação em UTI Geral do Hospital das Clínicas da Faculdade de Medicina de Botucatu no período de julho de 2007 a abril de 2008. RESULTADOS: A incidência de IRA foi de 31,2%. Os grupos foram semelhantes quanto ao sexo e diferiram quanto à etiologia da admissão em UTI (sepse: 31,7% x 13,1%, p < 0,0001, pós-operatório: 11% x 43%, p < 0,0001), idade (59,6 ± 18,1 x 50,2 ± 18,6 anos, p < 0,0001), APACHE II: (21 ± 11,1 x 11 ± 4,8, p = 0,002), oligúria (67,7% x 4,5%, p < 0,0001), presença de ventilação mecânica (81,7 x 57,7%, p = 0,0014), uso de drogas vasoativas (62,2 x 32,6%, p < 0,0001) e enfermaria de procedência (PS: 22 x 14,5%, p = 0,02 e centro cirúrgico: 42,7 x 62,6%, p = 0,03). Quanto às comorbidades, os grupos foram diferentes quanto à presença de HAS e IRC (42,6 x 35,9%, p = 0,005 e 15,8 x 2,1%, p = 0,04, respectivamente) e semelhantes quanto à presença de diabetes e ICC (19,5 x 11%, ns e 6 x 1,1%, ns, respectivamente). A mortalidade foi superior nos pacientes que contraíram IRA (62,1 x 16,5%, p < 0,0001). CONCLUSÃO: A incidência de IRA é elevada em UTI e presente em pacientes com parâmetros clínicos e índices prognósticos de maior gravidade, o que justifica a maior mortalidade observada neles.

Una metodología eficiente para manejo de restricciones en algoritmos evolutivos multi-objetivo

This paper presents a new approach for solving constraint optimization problems (COP) based on the philosophy of lexicographical goal programming. A two-phase methodology for solving COP using a multi-objective strategy is used. In the first phase, the objective function is completely disregarded and the entire search effort is directed towards finding a single feasible solution. In the second phase, the problem is treated as a bi-objective optimization problem, turning the constraint optimization into a two-objective optimization. The two resulting objectives are the original objective function and the constraint violation degree. In the first phase a methodology based on progressive hardening of soft constraints is proposed in order to find feasible solutions. The performance of the proposed methodology was tested on 11 well-known benchmark functions.

O papel das estatinas e da angioplastia percutânea renal no tratamento da doença renovascular aterosclerótica: estudo observacional

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudio observacional del contexto sociocognitivo de la catalogación de matérias em bibliotecas universitárias

A study of the subject indexing process in university libraries is presented, using a socio-cognitive approach to analyze the procedures, difficulties and perceptions of the librarians, users, and managers that take part in the process. Individual and group verbal protocols were applied in the real environment of the cataloguers, the university libraries. The results were the absence of systematic procedures for book subject analysis and representation, the incompatibility of the indexing language, and problems in subject retrieval from the catalog. It is concluded that there is a tendency in catalogs to act as databases. Therefore, the cataloguer should present a level of commitment in his task similar to that of an indexer who works in the production of bibliographic databases.

Plantas entre los juruna: en busca de una metodología para el estudio del léxico

This paper presents methodological considerations related to the study of the plant lexicon of the Juruna ethnic group, an indigenous people of the Xingu Indigenous Park, Mato Grosso State, Brazil. The language of this ethnic group, along with that spoken by the Xipaya, belongs to the Juruna family of the Tupi stock. It is a tonal language with SOV syntactic structure (Fargetti 1992, 2007), and presents interesting processes of reduplication (Fargetti 1997). Part of our broader research project on the lexicology and lexicography of the language, research on the Juruna plant lexicon is still in development, together with studies of other semantic fields such as birds, material culture, and kinship relations. However, it is already possible to see interesting linguistic issues involving word formation, as well as issues of the relationship between language and culture (especially those related to “perspectivism”). These issues are presented in this paper.

Design emocional e análise observacional: inter-relações entre produto e usuário

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)