Análise in silico de um novo “cluster” de PKS II Metagenômico

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

QTL for percentage of carcass and carcass parts in a broiler x layer cross

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

DIAGNOSIS of REGIONAL CEREBRAL BLOOD FLOW ABNORMALITIES USING SPECT: AGREEMENT BETWEEN INDIVIDUALIZED STATISTICAL PARAMETRIC MAPS and VISUAL INSPECTION BY NUCLEAR MEDICINE PHYSICIANS WITH DIFFERENT LEVELS of EXPERTISE IN NUCLEAR NEUROLOGY

INTRODUCTION: Visual analysis is widely used to interpret regional cerebral blood flow (rCBF) SPECT images in clinical practice despite its limitations. Automated methods are employed to investigate between-group rCBF differences in research Studies but have rarely been explored in individual analyses.OBJECTIVES: To compare visual inspection by nuclear physicians with the automated statistical parametric mapping program using a SPECT dataset of patients with neurological disorders and normal control images.METHODS: Using statistical parametric mapping, 14 SPECT images from patients with various neurological disorders were compared individually with a databank of 32 normal images using a statistical threshold of p<0.05 (corrected for multiple comparisons at the level of individual voxels or clusters). Statistical parametric mapping results were compared with Visual analyses by a nuclear physician highly experienced in neurology (A) as well as a nuclear physician with a general background of experience (B) who independently classified images as normal or altered, and determined the location of changes and the severity.RESULTS: of the 32 images of the normal databank, 4 generated maps showing rCBF abnormalities (p<0.05, corrected). Among the 14 images from patients with neurological disorders, 13 showed rCBF alterations. Statistical parametric mapping and physician A completely agreed on 84.37% and 64.28% of cases from the normal databank and neurological disorders, respectively. The agreement between statistical parametric mapping and ratings of physician B were lower (71.18% and 35.71%, respectively).CONCLUSION: Statistical parametric mapping replicated the findings described by the more experienced nuclear physician. This finding suggests that automated methods for individually analyzing rCBF SPECT images may be a valuable resource to complement visual inspection in clinical practice.

Curauá fibers in the automobile industry - a sustainability assessment

Replacing glass fibers with natural fibers in the automobile industry can yield economic, environmental and social benefits. This article evaluates the prospective environmental impacts of automobile applications of curauá fiber (Ananas erectifolius), which nearly equates the physical properties of glass fibers. The study identified economic and social advantages of applying curauá fiber composites in car parts. Besides costing 50% less than fiber glass, the use of curauá fibers can promote regional development in the Amazon region. In order to realize significant environmental benefits, however, the curauá-based composites would have to be lighter than their glass fiber-based counterparts. © 2006 Elsevier Ltd. All rights reserved.

Environmental evaluation of cogeneration scenarios in sugar industry

The development of new techniques that allow the analysis and optimization of energy systems bearing in mind environmental issues is indispensable in a world with finite natural resources and growing demand of energy. Among the energy systems that deserve special attention, cogeneration in the sugar industry must be pointed out, because it uses efficiently a common fuel for generation of useful heat and power. Within this frame, thermoeconomical optimization - 2nd Law of Thermodynamics analysis by exergy function and economic evaluation of the thermal system - gradually is taking importance as a powerful tool to assist to the decision making process. Also, the explicit consideration of environmental issues offers a better way to explore trade-offs between different aspects to support the decisions that must be made. In this work it is used the technique of Life Cycle Analysis (LCA) which allows to consider environmental matters as an integral part of the problem, in opposite to most of the environmental approaches that only reduce residuals generation , without taking into account impacts associated to other related processes. On the other hand, the consideration of environmental issues in optimization of energy systems is a novel and promissory contribution in the state of the art of energy optimization and LCA. The system under study is a sugar plant of Tucumán (Argentina) given the particular importance that this industry had inside the regional economy of the Argentinean Northwest. Although cogeneration comes being used a while ago in sugar industry, being the main objective the generation of heat and as secondary objective the electric power generation and mechanic power to cover several needs of working machineries, to the date it is no available a versatile tool that allows to analyze economical feasible alternatives bearing in mind environmental issues. At sugar plants, steam is generated in boilers using as fuel bagasse - cellulosic fiber waste obtained crushing the sugar cane- and it is used to give useful heat and shaft work to the plant, but it can also be used to generate electricity with export opportunities to the electrical network. The great number of process alternatives outlines a serious decision making problem in order to take advantage of the resources. Although the problem turns out to be a mixed non-linear problem (MINLP), the main contribution of this work is the development of a hybrid strategy to evaluate cogeneration alternatives that combines optimization approaches with environmental indicators. This powerful tool for its versatility and robustness to analyze cogeneration systems, will be of great help in the decision making process, because of their easy implementation to analyze the kind of problems presented in the sugar industry.

Non-conventional applications of computerized tomography: Analysis of solid dosage forms produced by pharmaceutical industry

X-ray computed tomography (CT) refers to the cross-sectional imaging of an object measuring the transmitted radiation at different directions. In this work, we describe a non-conventional application of computerized tomography: visualization and improvements in the understanding of some internal structural features of solid dosage forms. A micro-CT X-ray scanner, with a minimum resolution of 30 μm was used to characterize some pharmaceutical tablets, granules, controlled-release osmotic tablet and liquid-filled soft-gelatin capsules. The analysis presented in this work are essentially qualitative, but quantitative parameters, such as porosity, density distribution, tablets dimensions, etc. could also be obtained using the related CT techniques. © 2010 American Institute of Physics.

Responsabilidade social empresarial na indústria de calçados paulista: Uma análise dos pólos de franca e Birigui

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A expansão da agroindústria sucroalcooleira e a questão do desenvolvimento da microrregião de Dracena-SP

Pós-graduação em Geografia - FCT

Avaliação da qualidade da atenção básica nos municípios do Departamento Regional de Saúde de Sorocaba

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O enfoque da Ciência da Informação no contributo ao desenvolvimento sustentável regional: O caso do arquivo da ACIM

The archival institutions should for the elevation of the statistical indices of social and economic to integrate with sustainable development yours communities through regional entrepreneurship and improving informational. The Commerce and Industry Association of Marília (ACIM) archive provided to analyze the influence of the files on regional growth to development sustainable of industries and trade. The management theory and archives processes, set up data to create a model template guiding sustainable which suggested the results provided for: Transparency in the processes; global and local integration; culture and collaboration of the community; physical and human factors; improvement for work management and; to utilized to generate the economy of the ecosystem as a form of natural resources.

Desenvolvimento regional e sustentabilidade: a indústria intensiva em recursos naturais na região administrativa de Ribeirão Preto

The natural resource intensive industries have moved from center to periphery in Brazil. This shift is related to the environmental impacts generated by this type of industry, as occur biggest benefits to these industries in small towns as tax exemptions and donations of land, and local institutional capacity is lower in pollution control. In the 1970s began, in the state of São Paulo, a process of industrial deconcentration of Metropolitan Region of São Paulo to the inside of state, which generated an intense industrialization of the region of Campinas, Ribeirão Preto, Sorocaba e São José dos Campos. This process of industrial deconcentration had support in state policies restricting new industries in the Metropolitan Region and the creation and financing of infrastructure and improvement of road. This research project aims to verify whether there has been a shift of natural resource intensive industries for the Administrative Region of Ribeirão Preto, as well as aspects of the sustainability of this process