118 resultados para biometria ocular

em Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho"


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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This study aimed to describe and compare the ultrasonographic alterations in dogs' eyes submitted to facectomy with or without intraocular lens implant (IOL), to assist in the diagnosis of possible alterations related to the surgical procedure and IOL implantation. Nineteen dogs with cataract (21 eyes) were submitted to phacoemulsification and late postoperative evaluation (at five years). The animals were initially submitted to complete ophthalmological exams which preceded the sonogram. Dogs were divided in three groups: (CA) aphakic dogs (n= 11); (PP) pseudophakic dogs with implantation of two IOLs in piggyback (n=5) and (PL) pseudophakic dogs with implantation of a veterinary IOL (n = 5). The ultrasound was carried under the administration of a topic local anesthetic, with a multi frequency linear transducer of 10 MHz. Biometric eye measurements were also performed. The clinical alterations observed were IOL dislocation, retinal detachment, asteroid hyalosis, and vitreous degeneration. Ultrasound examination was an excellent diagnostic tool, as it was possible to confirm and classify these changes. The piggyback implant reduced the measurements between the ciliary body and the vitreous chamber obtained from the ocular biometry when compared to other usual procedures, with no difference between the axial length and the anterior chamber.

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Pós-graduação em Cirurgia Veterinária - FCAV

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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This study analyze the consequences of unilateral and bilateral ablation based on ovigerous percentage, consecutive spawns, and secondary effects of the surgical process in the females of Macrobrachium rosenbergii (De Man, 1879). Two experiments were carried out with four and seven months old females in intermolt stage. Each experiment was comprised of control, unilateral and bilateral ablation. Eyestalk ablation was done with a bistoury with a topic hot cauterization followed by application of antibiotic pomades. The animals were maintained at constant temperature (28 ± 1,05ºC) and photoperiod of 12L: 12D within fibercement boxes with sandy bottom and biological filter. Females were observed once a day during fourteen weeks, registering gonadal condition, ecdysis and presence of spermatophore (mating) and spawning. Unilateral ablation technique is more efficient due to the anticipation of the first spawn, repeatability between spawns, expressive rate of ovigerous females and survival, that favored its applicability. Bilateral eyestalk ablation produced the mortality of ali the females with change in coloration and food activity patterns. These results corroborate other observations on penaeid shrimps. though bilateral ablation on some lobsters was a success. These results showing an interespecific variation and can be used in aquaculture projects.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Quarenta bovinos machos, com peso médio de 371 kg, foram distribuídos em um delineamento em blocos casualizado com esquema fatorial 3x3, dos quais quatro foram abatidos no início do experimento como referência, para avaliar a biometria das carcaças e o peso de vísceras e órgãos internos quando alimentados com diferentes fontes protéicas (uréia, Amiferm e farelo de soja) e volumosos (cana-de-açúcar e a silagem de milho e pastagem de capim Brachiaria brizantha). Não houve interação significativa volumosos x fontes protéicas e não houve diferença significativa entre as fontes protéicas para os parâmetros estudados. Para os volumosos, os pesos (em porcentagem do peso do corpo vazio - % PCV) do conteúdo estomacal (CRROA) e do conteúdo gastrintestinal (CGI) foram significativamente maiores para os animais alimentados com cana-de-açúcar (7,52 e 8,59% PCV, respectivamente) e não diferiram entre os alimentados com silagem de milho e capim, com médias de 5,10% PCV, para CRROA, e 5,89% PCV para CGI. Os animais mantidos em pastagem não apresentaram compacidade das carcaças diferente dos animais alimentados com os outros volumosos, enquanto os alimentados com cana-de-açúcar mostraram ser menos compactos que os alimentados com silagem de milho. As fontes protéicas também influenciaram a compacidade, que foi menor nos animais que receberam Amiferm e iguais para os que receberam uréia e farelo de soja. Conclui-se que os animais alimentados com cana-de-açúcar apresentam maior enchimento dos compartimentos digestivos e carcaças menos compactas.

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Importance of the field: The use of topical agents poses unique and challenging hurdles for drug delivery. Topical steroids effectively control ocular inflammation, but are associated with the well-recognized dilemma of patient compliance. Although administration of topical antimicrobials as prophylaxis is acceptable among ophthalmologists, this common practice has no sound evidence base Developing a new antimicrobial agent or delivery strategy with enhanced penetration by considering the anatomical and physiological constraints exerted by the barriers of the eye is not a commonly perceived strategy. Exploiting the permeability of the sclera, subconjunctival routes may offer a promising alternative for enhanced drug delivery and tissue targeting.Area covered in this review: Ocular drug delivery strategies were reviewed for ocular inflammation and infections clinically adopted for newer class of antimicrobials, which use a multipronged approach to limit risks of endophthalmitis.What the reader will gain: The analysis substantiates a new transscleral drug delivery therapeutic approach for cataract surgery.Take home message: A new anti-inflammatory and anti-infective paradigm that frees the patient from the nuisance of topical therapeutics is introduced, opening a large investigative avenue for future improved therapies.