Uso de medicações por via subaracnóidea no tratamento da dor crônica

JUSTIFICATIVA E OBJETIVOS: A dor crônica é um desafio para a Medicina atual. Novos métodos e medicamentos têm sido propostos com o intuito de controlar os sintomas álgicos. A via de administração subaracnóidea tem se mostrado como uma alternativa viável e segura, embora necessite continuamente ser objeto de estudo de muitos pesquisadores. O objetivo deste trabalho é fazer uma revisão dos medicamentos disponíveis no arsenal terapêutico já consagrados pelo uso e os que se mostram promissores na atualidade para a prática clínica diária. CONTEÚDO: Nesta revisão são avaliados vários fármacos que apresentam ação analgésica quando utilizada via neuroeixo. Opióides, anestésicos locais, agonistas alfa2-adrenérgicos, antagonistas dos aminoácidos excitatórios e inibitórios, acetilcolina, inibidores da acetilcolinesterase, bloqueadores dos canais de cálcio, adenosina, serotonina, antidepressivos tricíclicos e inibidores da síntese de prostaglandinas são analisados no que concerne aos seus efeitos farmacológicos, incluindo os indesejáveis. CONCLUSÕES: Muitos avanços foram registrados no controle dos sintomas álgicos após a utilização das substâncias citadas por via raquidiana, onde certamente algumas serão aproveitadas e enriquecerão o arsenal terapêutico e outras relegadas temporária ou definitivamente. Entretanto, ainda serão necessários muitos estudos clínicos e experimentais para que estes conhecimentos possam ser incorporados e utilizados com segurança pelos profissionais que lidam com o tratamento da dor crônica.

Acompanhamento da dinâmica do uso do solo em uma bacia hidrográfica no Município de Botucatu (SP) por meio de geotecnologia

The increasing expansion of agricultural activities, without considering the potential and limitations of soils is a potential source of environmental degradation. Thus, the present study assessed the variation of use and occupation in 49 years, between 1962 and 2011 scenarios of watershed of São Caetano - Botucatu (SP). geoprocessing techniques were used in this study. In a Geographic Information System (GIS) - IDRISI – it was integrated information from IBGE digital cards, scale 1:50,000, plus aerial photographs (1962) and satellite images LANDSAT - 5 (2011). In the study area, we can view the progress of the urban area, which in 1962 was not present in the watershed. In 2011, the urban area occupied 21.37% of the total area. Even with this breakthrough occurring in the period of 49 years, there was an increase in the area of natural vegetation, which once occupied only 12.33% of the area (1962), and in 2011 represents 25% of the total area of the watershed, showing an increase in awareness on the importance of preserving nature. Thus, we can conclude that the analysis tools based on GIS enabled us to analyze variations in space and time and to propose alternatives to the correct use and occupation of land.

Análise do conflito do uso e ocupação da terra em área de preservação permanente através do SIG

This study aimed to map the classes of use and occupation and their conflicts in Areas of Permanent Preservation (APPs) in the basin of Ribeirão São Pedro - Botucatu (SP) with the use of remote sensing techniques - image obtained by satellite 2011 - and the use of GIS. For this, we used the GIS techniques, and the integration of information held in the Geographic Information System (GIS) - IDRISI, coupled with the use of digital maps, published by the Brazilian Institute of Geography and Statistics - IBGE, scale 1: 50,000 and satellite images LANDSAT - 5 (2011) sensor TM (Thematic Mapper) with spatial resolution of 30 x 30 meters, provided by the National Institute for Space Research (INPE) .The Geographic Information System (GIS) was used IDRISI Selva and software, CartaLinx. This work had as legal support environmental legislation, specifically, the Federal Law 12.651 / 12. Thus, the study of the watershed becomes an important tool to understand its dynamics in relation to the use and occupation of their area and to characterize their environmental problems and taking as legal counsel to the preservation and conservation of the land to support environmental legislation.

Sistema de Informações Geográficas aplicado ao diagnóstico do uso da terra da bacia hidrográfica do Córrego São Caetano - Botucatu (SP)

The study aimed to obtain the land use of the watershed Stream São Caetano - Botucatu (SP), through the satellite image. The cartographic databases were: planialtimetric letter in digital format (IBGE) used in georeferencing, and satellite image. Geographic Information Systems (GIS) -IDRISI Selva was use to perform the image georeferencing and to do the final thematic map. In the software CAD - CartaLinx, it was performed the delimitation of the area under study (boundary, drainage network and areas of use and coverage). The land use of the watershed showed that pasture was the class which occupied most of the area, with 34.51% (1117,94 ha), the remainder of the area was urban (692,19ha), forests (809,79ha), cultures (599,96ha) and a very small part of reforestation (19,53ha). The use of remote sensing and geoprocessing were very satisfactory in the present work. Technologies must be increasingly used in agricultural and environmental studies, because technological tools, such as Geographic Information System (GIS), present speed, efficiency, reliable results, helping in increasing sustainability