De Sitter Relativity: a New Road to Quantum Gravity?

The Poincar, group generalizes the Galilei group for high-velocity kinematics. The de Sitter group is assumed to go one step further, generalizing Poincar, as the group governing high-energy kinematics. In other words, ordinary special relativity is here replaced by de Sitter relativity. In this theory, the cosmological constant I > is no longer a free parameter, and can be determined in terms of other quantities. When applied to the whole universe, it is able to predict the value of I > and to explain the cosmic coincidence. When applied to the propagation of ultra-high energy photons, it gives a good estimate of the time delay observed in extragalactic gamma-ray flares. It can, for this reason, be considered a new paradigm to approach the quantum gravity problem.

Cadmium stress antioxidant responses and root-to-shoot communication in grafted tomato plants

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Mobile application as a tool for urban traffic data collection and generation to advanced traveler information systems using Wi-Fi networks available in urban centers

This paper presents an Advanced Traveler Information System (ATIS) developed on Android platform, which is open source and free. The developed application has as its main objective the free use of a Vehicle-to- Infrastructure (V2I) communication through the wireless network access points available in urban centers. In addition to providing the necessary information for an Intelligent Transportation System (ITS) to a central server, the application also receives the traffic data close to the vehicle. Once obtained this traffic information, the application displays them to the driver in a clear and efficient way, allowing the user to make decisions about his route in real time. The application was tested in a real environment and the results are presented in the article. In conclusion we present the benefits of this application. © 2012 IEEE.

How Communication experts express communicative competence

Este estudo teve por objetivo compreender como especialistas brasileiros em comunicação expressam sua competência comunicativa. Investigou-se um grupo de professores universitários de enfermagem, especialistas na área de comunicação, utilizando-se a seguinte pergunta norteadora: Como você expressa sua competência comunicativa? Os entrevistados referiram expressar sua competência comunicativa vivenciando-a em sua vida profissional e em sua rotina diária, ouvindo outras pessoas, percebendo a comunicação não-verbal, validando a compreensão de mensagens, quebrando barreiras de comunicação, demonstrando afetividade e desenvolvendo o autoconhecimento. Os resultados obtidos a partir deste estudo nos permitiram compreender a comunicação como algo a ser aprendido, sentido e vivenciado, ou seja, percebendo as nossas próprias emoções e sentimentos assim como os de outras pessoas, tanto no cuidado em enfermagem quanto em ações da vida diária.

Modulation of intercellular communication in macrophages: possible interactions between GAP junctions and P2 receptors

Gap junctions are connexin-formed channels that play an important role in intercellular communication in most cell types. In the immune system, specifically in macrophages, the expression of connexins and the establishment of functional gap junctions are still controversial issues. Macrophages express P2X(7) receptors that, once activated by the binding of extracellular ATP, lead to the opening of transmembrane pores permeable to molecules of up to 900 Da. There is evidence suggesting an interplay between gap junctions and P2 receptors in different cell systems. Thus, we used ATP-sensitive and -insensitive J774.G8 macrophage cell lines to investigate this interplay. To study junctional communication in J774-macrophage-like cells, we assessed cell-to-cell communication by microinjecting Lucifer Yellow. Confluent cultures of ATP-sensitive J774 cells (ATP-s cells) are coupled, whereas ATP-insensitive J774 cells (ATP-i cells), derived by overexposing J774 cells to extracellular ATP until they do not display the phenomenon of ATP-induced permeabilization, are essentially uncoupled. Western-blot and reverse-transcription polymerase chain reaction assays revealed that ATP-s and ATP-i cells express connexin43 (Cx43), whereas only ATP-s cells express the P2X(7) receptor. Accordingly, ATP-i cells did not display any detectable ATP-induced current under whole-cell patch-clamp recordings. Using immunofluorescence microscopy, Cx43 reactivity was found at the cell surface and in regions of cell-cell contact of ATP-s cells, whereas, in ATP-i cells, Cx43 immunoreactivity was only present in cytosolic compartments. Using confocal microscopy, it is shown here that, in ATP-s cells as well as in peritoneal macrophages, Cx43 and P2X(7) receptors are co-localized to the membrane of ATP-s cells and peritoneal macrophages.

Arquitetura Orientada a Serviços baseada na Tecnologia Jini: um caso de teste em Computação Ubíqua

T he people’s daily lives are surrounded by computing devices, with increasing resources (sensors) and, with increasing processing. How these devices communicate is still not natural and This retards the growth of Ubiquitous Computing. This paper presents a way in which these devices can communicate using Jini technology and concepts of Service Oriented Architecture, applying these concepts in a test case of Ubiquitous Computing. To conduct the test case was constructed a fictitious system for management of a soccer championship, where users can interact with each other and with the system in a simplified way, have access to data in real time of the championship during the event. This communication is performed by services built using Jini technology, which were based on key SOA concepts, such as modularity and reusability

Editoração eletrônica: novos comportamentos editoriais e estéticos

This dissertation shows a new tool in the process of producing specialized printed media: desktop publishing. Because it is an important tool to this communication media, the visualization of its evolutionary journey began in the pre-history of informative vehicle, advancing to the informatics society. And it was just in this last social stage that desktop publishing legitimized its function, resulting in impacts on the production of these media and conditioned new styles. At the presentation of this new post-industrial society, a change of work and leisure sphere was verified, whose fusion is present and in this interaction, desktop publishing arose at home, in the little bureaus. In this journey, desktop publishing became an object of reflection because of its conditioning aspects that fostered moments of observation in relation to a possible threat to creativity, thanks to its facilities and clichés. On the other hand, different positive aspects of desktop we also shown, at the same time, its conditioning aspects resulting into a restudy of its execution in different printed media, showing its effects and sharing points of view. So, new styles and a editorial way of production were seen too. Add to this aspect desktop publishing – in general meaning – the computerization of magazine articles – has been producing resignation of journalists, which is another important aspect in the presenting dissertation.

Informatização: impactos editoriais e estéticos

This dissertation shows a new tool in the process of producing specialized printed media: desktop publishing. Because it is an important tool to this communication media, the visualization of its evolutionary journey began in the pre-history of informative vehicle, advancing to the informatics society. And it was just in this last social stage that desktop publishing legitimated its function, resulting in impacts on the production of these media and conditioned new styles. At the presentation of this new post-industrial society, a change of work and leisure sphere was verified, whose fusion is present and in this iteration, desktop publishing arose at home, in the little bureau. In this journey, desktop publishing became an object of reflection because of its conditioning aspects that fostered moments of observation in relation to a possible threat to creativity, thanks to its facilities and clichés. On the other hand, different positive aspects of desktop were also shown, at the same time, its conditioning aspects resulting into a restudy of its execution in different printed medias, showing its effects and sharing points of view. So, new styles and an editorial way of production were seen as well. Add to this aspect, desktop publishing – in general meanings – the informatization of magazine offices – has been producing dismissing of journalists, which is another important aspect in the presenting dissertation.

Síndrome de Silver-Russell: relato de caso

OBJETIVO: descrever o fenótipo da síndrome de Silver-Russell (SSR) e apresentar um caso diagnosticado com esta afecção genética, abordando aspectos genéticos, psicológicos e fonoaudiológicos. MÉTODOS: trata-se de relato de caso de uma criança do gênero feminino, sete anos e onze meses, portadora da síndrome de Silver-Russel. Foram realizadas avaliação genética médica e molecular, avaliação psicológica, avaliação fonoaudiológica e aplicação de testes complementares. RESULTADOS: a análise molecular da região 7p11 excluiu a dissomia uniparental para este caso. No exame físico foram constatados os principais sinais clínicos da SSR que incluiu retardo no crescimento de origem pré-natal, fácies típica, assimetrias ósseas e clinodactilia do 5º dedo. A avaliação cognitiva e fonoaudiológica mostraram deficiência mental, distúrbio de linguagem oral e comprometimento das funções orais. CONCLUSÃO: o estudo deste caso possibilitou a divulgação do fenótipo da SSR com suas manifestações físicas, cognitivas e fonoaudiológicas. Embora o teste molecular não tenha confirmado um dos possíveis mecanismos etiológicos da síndrome, a avaliação genética médica constatou a presença dos principais sinais clínicos que foram correlacionados à literatura. A avaliação psicológica e fonoaudiológica apontaram para comprometimento cognitivo e de comunicação, funções orais , sugerindo que importantes alterações fonoaudiológicas podem fazer parte do fenótipo desta síndrome, ainda pouco difundida para fonoaudiólogos.

Produção científica publicada nos Anais Brasileiros de Dermatologia (2003-2007)

BACKGROUND - The scientific production of dermatology is not very known and studied in quantitative and qualitative aspects in Brazil.OBJECTIVE - To study the characteristics of the Brazilian scientific production published on the Anais Brasileiros de Dermatologia from 2003 to 2007.METHODS - A transversal study of articles published on the clinical, epidemiological, laboratory and therapeutic investigation, - case report and 'communication sections of the Anais Brasileiros de Dermatologia, from 2003 to 2007, were reviewed. The variables studied were: the dermatological subspecialty focused, methodological analysis used; diseases or disorders investigated and the understanding of authors related to the communication section.RESULTS - Among investigational manuscripts, clinical studies prevailed (60.3%), those with surgical or cosmetic interest accounted for 13%. Descriptive and observational studies were the most common (81.9%), particularly the case series (50%). Infectious (33.6%) and inflammatory disease (28.6%.) was the subject of investigation or case report, respectively, Case report was the most common subject on the communication section.CONCLUSION - Descriptive methods were predominant among the research articles published in the studied period. More sophisticated and elaborated methods were uncommon. Research designs and critical analysis of the scientific literature must be part of the curriculum of the graduate and residency programs in dermatology.

Enhanced airways responsiveness in rats depleted of sensory neuropeptides by neonatal capsaicin treatment

This study aimed to investigate the in vivo and in vitro reactivity of airway smooth muscle in rats depleted of sensory neuropeptides by treatment with capsaicin at neonatal stage. Wistar rats were neonatally injected with either capsaicin (50 mg/kg, s.c., 2nd day of life) or its vehicle (10% ethanol and 10% Tween 80, in 0.9% w/v NaCl solution) and used at adult ages (60-70 days later). Analysis of the lungs showed a higher number of infiltrating neutrophils, eosinophils and mononuclear cells into the peribronchiolar regions of capsaicin-pretreated rats compared to vehicle group. This was associated with a higher contraction index of bronchiolar wall in the capsaicin group. The in vitro tracheal reactivity in response to methacholine (full muscarinic agonist) and pilocarpine (partial muscarinic agonist) was also significantly higher in capsaicin-pretreated rats compared to vehicle group. In conclusion, the neuropeptide depletion by capsaicin neonatal treatment lead to marked contraction of the rat airways at adult age, suggesting a protective role for C fibers in the lungs. (C) 2003 Elsevier B.V. Ireland Ltd. All rights reserved.

A comunicação como barreira à inclusão de alunos com deficiência visual em aulas de óptica

O presente artigo representa uma continuidade dos resultados apresentados em Camargo e Nardi (Revista Brasileira de Ensino de Física 29, 117 (2007)). Encontra-se inserido dentro de um estudo que busca compreender as principais barreiras para a inclusão de alunos com deficiência visual no contexto do ensino de física. Focalizando aulas de óptica, analisa as dificuldades comunicacionais entre licenciandos e discentes com deficiência visual. Para tal, enfatiza as estruturas empírica e semântico-sensorial das linguagens utilizadas, indicando fatores geradores de dificuldades de acessibilidade nas informações veiculadas. Recomenda, ainda, alternativas que visam dar condições à participação efetiva do discente com deficiência visual no processo comunicativo, das quais destacam-se: a identificação da estrutura semântico-sensorial dos significados veiculados, o conhecimento da história visual do aluno, a destituição da estrutura empírica audiovisual interdependente e a exploração das potencialidades comunicacionais das linguagens constituídas de estruturas empíricas de acesso visualmente independente. Conclui afirmando que a comunicação representa a principal barreira à participação efetiva de alunos com deficiência visual em aulas de óptica e enfatiza a importância da criação de canais comunicacionais adequados como condição básica à inclusão desses alunos.

Referral letters in oral medicine: an approach for the general dental practitioner

The aim of this study was to analyze the contents of referral letters related to clinical history and reason for consultation. A total of 236 consecutive referral letters were evaluated. Analysis of the referral letters was based on key items concerning patient identification. chief complaint, previous consultation. laboratory investigation and use of drugs for the chief complaint. A database was organized (Epinfo 6.04) and the chi (2) test (a = 0.05) was applied to the results. of the 800 files examined. only 30%, (236) had a referral letter. of the 236 referral letters. 67% were from dentists, 22% from physicians and 11% from unidentified professionals. Patient age did not appear in 70%, of the letters and the chief complaint was mentioned only in 55%. The letters had no details such as description of the oral lesion (80%), anatomical site (34%), size (99%), symptoms (83%), or period of evolution (92%). Clinical diagnosis was not included in 84% of the letters. Less than 5% of the referral letters contained information about previous consultation and laboratory investigation. The chi (2) test showed significant differences for ail items of the referral letter. Referral letters did not satisfy minimal requirements about clinical history or reason for consultation. leading to failed communication among professionals. Based on this study, we suggest that standard letters are important to improve the quality of the letters, reducing the rate of omission of relevant items.

Pt(II) and Ag(I) complexes with acesulfame: Crystal structure and a study of their antitumoral, antimicrobial and antiviral activities

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Equivalência lexical e aspectos morfológicos de termos em português e espanhol do domínio da dermatologia

Pós-graduação em Estudos Linguísticos - IBILCE