Dimensões geométricas das fibras do músculo sóleo de ratos exercitados em esteira rolante: a importância da análise por meio de imagens digitalizadas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relação entre a esfericidade, a função ventricular e o tamanho do infarto em ratos

FUNDAMENTO: A esfericidade do ventrículo esquerdo (VE) é fator associado com disfunção ventricular, mas não está bem caracterizada no modelo de ratos infartados. OBJETIVO: Analisar a relação entre o índice de esfericidade, a função ventricular e a área infartada no modelo experimental em ratos. MÉTODOS: Seis meses após infarto (IAM, n=33) ou cirurgia simulada (SHAM, n=18), os animais foram submetidos a ecocardiograma. O índice de esfericidade foi obtido pela razão entre as áreas diastólicas nos eixos maior e menor do VE. RESULTADOS: O grupo IAM apresentou menor índice de esfericidade (1,32 × 0,23 vs 1,57 × 0,33; p=0,002), de função sistólica e espessura relativa (0,13 × 0,003 vs 0,18 × 0,04; p<0,001) e maior índice de estresse parietal (1,27 × 0,33 vs 0,88 × 0,25; p<0,001). Houve correlação significativa entre tamanho do infarto e esfericidade (p=0,046). Na análise de regressão linear, o tamanho de infarto (p=0,014), mas não a esfericidade (p=0,683) e o estresse parietal (p=0,176), foi fator de predição da função sistólica. Remodelação excêntrica (p=0,011), mas não a esfericidade (p=0,183) ou o tamanho de infarto (p=0,101), foi fator preditor do estresse parietal. Adicionalmente, o tamanho do infarto (p=0,046), mas não remodelação excêntrica (0,705), foi fator preditor da esfericidade. O tamanho do infarto (p=0,015) e o estresse parietal (p=0,011), mas não a esfericidade (p=0,705), foram preditores de remodelação excêntrica. CONCLUSÃO: A esfericidade está associada mas não é fator determinante do estresse parietal, da remodelação excêntrica e da função sistólica ventricular no modelo de infarto experimental em ratos.

Una lapide in via Mazzini: os sofrimentos em Auschwitz e os desafios da tradução

Giorgio Bassani in his book Una lapide in via Mazzin seeks to show to the readers all the sufferings passed by Italians during the Second World War and emphasized those persists until today. Aiming to make an unprecedented translation of this tale, it is expected that the text provides us great experiences in the language and we could see the actual difficulties and differences with the Portuguese language, despite being considered these languages closed ones. The objective of this work is to produce a translation that allows us to transmit all anxieties and reflections suffered by the main character of the tale. After the war, the survivor of the concentration camp can go back to your city. He appears exactly at the moment is being placed a headstone on the synagogue wall in homage to Jews deported and killed in the camps. Given the gaunt figure of the man with his striped pajamas, the population is driven to rethink their own indifference and , in a way, its share of blame. Thus, the return should be celebrated is rejected and the figure of the survivor becomes a nuisance. The function of the headstone is actually and literally put a stone on the story. To achieve the proposed objective for this work, we analyzed all the chapters of the story Una lapide in via Mazzini and tried to find equivalents in Portuguese. However, we not ignored the traces of meaning that Giorgio Bassani invested in his work. Therefore, it was necessary to use both printed and virtual dictionaries. With the advancement of the translation work, we realized the difficulty of finding appropriate solutions to achieve the desired effect . The fidelity proposed by the author became increasingly difficult as our work progressed. In the course of all the discussions, it was concluded that , in fact , when it comes to translation, maintaining fidelity to the original text in a foreign language is a difficult and laborious process

Comparación de la conductancia hidráulica dentinaria, de acuerdo al tiempo de aplicación de desensibilizantes con base de oxalatos

ABSTRACT. Introduction: an in vitro model was used to measure the hydraulic conductance in human dentin discs treated with oxalic acid for 15, 30 or 60 s maintaining the occlusive effect and measuring 7 and 14 days after application. Methods: 45 dentin discs measuring 1 mm thick were obtained from human third molars which were free of caries and in no occlusion; the samples were obtained from patients aged 16 to 30 years. Discs were sorted out into three study groups (n = 15) depending on the time of application of a commercial solution of oxalate-based dentin desensitizer (DD) (BisBlock®) which contains ˂ 5% oxalic acid of 1.5-1.8 pH: in group A the agent was applied for 15 s, in group B it was applied for 30 s, and in group C for 60 s. The hydraulic conductance of each disc was calculated after acid etching, which corresponds to the maximum permeability of discs (100%) after immediate application of oxalic acid, as well as seven and fourteen days of storage in saline solution. The statistical analysis was done with ANOVA test and post-hoc Games-Howell test. Results: 35,46 ± 23.41% in Group A, 36.34 ± 15.88% in Group B and 24.99 ± 14.99% in Group C, showing that the use of DD for 15, 30 or 60 s decreased permeability in a statistically significant manner (p <0.05). Conclusions: DD was effective in reducing hydraulic conductance regardless of application time, but this reduction was temporary only, since after seven days permeability returns to values close to those of baseline.

Efecto Insecticida del Extracto de Semillas de Neem (Azadirachta indica A. Juss) sobre Collaria scenica Stal (Hemiptera: Miridae)

This work was developed with the objetive to evaluate the insecticidal effect of the Neem (Azadirachta indica A. Juss) seeds against grass bug nymphs Collaria scenica Stal. For that, an extract was prepared from green fruits of Neem by rotaevaporacion. The extract was diluted in three ppm concentrations corresponding to treatments. Using thin-layer chromatography we identified the presence of Azaridactina. DCA essay was carried out with 4 treatments and 5 repetitions that included the three extract concentrations and a control. In each repetition were used 15 nymphs, randomly placed in plastic boxes with food and the corresponding concentration. Every day an extract application was made and recorded mortality percentage, number of exuviae and number of individuals who came to adulthood in each treatment. The results were analyzed using Kruskal-Wallis and Games-Howell for each variable. The three concentrations of Neem seed extract had a negative effect on the development of the bugs. The more concentrated treatment (250 ppm) was the most effective, showing a 97% mortality, fewer exuvias and and fewer adults in the end of the experiment.

Efecto del método de secado en las propiedades termodinámicas de pulpa de mora en polvo

Three different types of maltodextrin encapsulated dehydrated blackberry fruit powders were obtained using vibrofluidized bed drying (VF), spray drying (SD), vacuum drying (VD), and freeze drying (FD). Moisture equilibrium data of blackberry pulp powders with 18% maltodextrin were determined at 20, 30, 40, and 50°C using the static gravimetric method for the water activity range of 0.06-0.90. Experimental equilibrium moisture content data versus water activity were fit to the Guggenheim-Anderson-de Boer (GAB) model. Agreement was found between experimental and calculated values. The isosteric heat of sorption of water was determined using the Clausius-Clapeyron equation from the equilibrium data; isosteric heats of sorption were found to increase with increasing temperature and could be adjusted by an exponential relationship. For freeze dried, vibrofluidized, and vacuum dried pulp powder samples, the isosteric heats of sorption were lower (more negative) than those calculated for spray dried samples. The enthalpy-entropy compensation theory was applied to sorption isotherms and plots of ΔH versus ΔS provided the isokinetic temperatures, indicating an enthalpy-controlled sorption process.

Efecto del blanqueamiento dental con peroxido de hidrógeno al 35% en la resistencia de unión de dientes restaurados con resina compuesta

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efecto del ácido oxálico bajo restauraciones cervicales en dientes con hipersensibilidad: ensayo clínico randomizado controlado doble ciego

To evaluate the effect of oxalic acid in cervical hypersensitivity, used under two different resin restorations one based on methacrylate and another based on silorane. Methods: 19 patients with “LCNC with hypersensitivity” were distributed into 4 groups according to treatment: G1 (n = 31): 0.5% oxalic acid (Desenssiv, SSWhite) + Z250 (3MESPE), G2 (n = 31): 0.5% oxalic acid + Filtek Silorane - P90 (3MESPE), G3 (n = 30): Distilled water + Z250; G4 (n = 30): Distilled water + Filtek Silorane - P90. Two clinical calibrated (kappa> 0.75) evaluated the sensitivity of the teeth: Before treatment, at 30, 60 and 90 days post-treatment (VAS). Results: The 4 groups at 30, 60 and 90 days reduced HS compared with the baseline (p <0.05). G1 and G2 showed less HS than G3 and G4 (p <0.05). Conclusion: The 4 restorative procedures significantly reduce the hypersensitivity, 30, 60 and 90 days compared to the baseline.