A assessoria do Serviço Social na gestão das políticas públicas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise da direção ético política do Assistente Social na perspectiva do projeto hegemônico profissional

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A relação entre o espaço e a saúde bucal coletiva: por uma epidemiologia georreferenciada

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Natural Conditions and Environmental Impacts in a Coastal Hydrographic Basin in the Brazilian Amazon

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Arranjo produtivo rural: o agrocomércio da uva no município de Jundiaí - SP

Pós-graduação em Geografia - IGCE

A criatividade produtiva e as ressonâncias emocionais das atividades físicas de aventura na natureza

Pós-graduação em Ciências da Motricidade - IBRC

Transformações do planejamento urbano em cidades de porte médio e em cidades médias brasileiras

Pós-graduação em Geografia - FCT

Gestão democrática no contexto das reformas educacionais na América Latina

Pós-graduação em Educação - FFC

Fluxos da alteridade: organizações negras e processos identitários no Nordeste Paulista e Triângulo Mineiro (1930-1990)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A poesia do romance: Memorial de Aires, um caso exemplar

Pós-graduação em Letras - IBILCE

O neopentecostalismo e os dilemas da modernidade periférica sob o signo do novo desenvolvimentismo brasileiro

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A qualidade do ensino em uma escola pública estadual: um estudo das práticas da equipe gestora

Pós-graduação em Educação Escolar - FCLAR

Releitura eliasiana de Sérgio Buarque de Holanda: democracia e personalismo no Brasil contemporâneo

Pós-graduação em Ciências Sociais - FFC

As dimensões geográficas dos Arranjos Produtivos Locais

This article aims to further discuss the Local Productive Arrangements (APLs), considering some geographical visions thinking about spatial configuration and the economic and social processes that characterize them, configuring a wide range of territorialities and productive territories that mark the landscape current Brazilian. In this sense, APLs are present today in both the figure of those who study analytical concept for regional development, and as a public policy supporting networks and supply chains in their territorial bases, especially small businesses. Thus, this arrangements can be read, geographically, as territorial productive specializations that are configured in spatial circuits of production, integrated with other regions, localities and supply chains through the morphology of networks and districts and grounded in networks of urban networks of material and immaterial flows which are bringing urban centers of different sizes. Considering the multidimensionality of the subject, the clusters have certain weaknesses in terms of their assumptions and perspectives, especially the limitations of the tool if designed just for resources and policies applied at the local level. Suggest the approach of a "geography of APLs" is to seek treat it from a territorial and socio reading.

Mass spectrometric characterization of two novel inflammatory peptides from the venom of the social wasp Polybia paulista

The social wasp P. paulista is relatively common in southeast Brazil causing many medically important stinging incidents. The seriousness of these incidents is dependent on the amount of venom inoculated by the wasps into the victims, and the characteristic envenomation symptoms are strongly dependent on the types of peptides present in the venom. In order to identify some of these naturally occurring peptides available in very low amounts, an analytical protocol was developed that uses a combination of reversed-phase and normal-phase high-performance liquid chromatography (HPLC) of wasp venom for peptide purification, with matrix-assisted laser desorption/ionization time-of-flight post-source decay mass spectrometry (MALDI-Tof-PSD-MS) and low-energy collision-induced dissociation (CID) in a quadrupole time-of-flight tandem mass spectrometry (QTof-MS/MS) instrument for peptide sequencing at the sub-picomole level. The distinction between Leu and Ile was achieved both by observing d-type fragment ions obtained under CID conditions and by comparison of retention times of the natural peptides and their synthetic counterparts (with different combinations of I and/or L at N- and C-terminal positions). To distinguish the isobaric residues K and Q, acetylation of peptides was followed by Q-Tof-MS analysis. The primary sequences obtained were INWLKLGKMVIDAL-NH2 (MW 1611.98Da) and IDWLKLGKMVMDVL-NH2 (MW 1658.98Da). Micro-scale bioassay protocols characterized both peptides as presenting potent hemolytic action, mast cell degranulation, and chemotaxis of poly-morphonucleated leukocyte (PMNL) cells. The primary sequences and the bioassay results suggest that these toxins constitute members of a new sub-class of mastoparan toxins, directly involved in the occurrence of inflammatory processes after wasp stinging. Copyright (C) 2004 John Wiley Sons, Ltd.