28 resultados para Romberg

em Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho"


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The objective of this study is to present the trajectory of a research project (ALLEVATO, 2005) whose phenomenon of interest is the teaching of mathematics using problem solving with computers. The text is an attempt to portray this trajectory, from the point of view of the methodological route followed by the researcher, which was based on two main axes: the guidance of the educator Thomas A. Romberg (1992), and the guidelines provided by the foundations of qualitative research. The study was developed during a doctoral course offered by the Graduate Program in Mathematics Education at the State University of São Paulo (UNESP), Rio Claro campus.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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O objetivo é relatar o caso de portadora de atrofia hemifacial progressiva, atendida na Faculdade de Medicina de Botucatu-UNESP: A paciente do sexo feminino, 43 anos, branca, queixava-se de afundamento progressivo do olho esquerdo e região orbitária há aproximadamente 10 anos, com dor na região periorbitária ipsilateral e diminuição da acuidade visual. O exame tomográfico confirmou a hipótese e o tratamento foi feito com injeção de Polietigel® na órbita, com bom resultado estético e melhora da função palpebral. O Polietigel pode ser uma alternativa para o tratamento do enoftalmo na síndrome de Parry-Romberg.

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Progressive facial hemiatrophy (Romberg's syndrome) is of unknown cause and uncertain pathogenesis. The main pathogenetic hypotheses are: sympathetic system alterations, localized scleroderma, trigeminal changes, possibly of genetic origin. To test the hypothesis of sympathetic system alterations, we designed an experimental model with ablation of the superior cervical sympathetic ganglion in rabbits, cats and dogs. All the animals were operated upon when 30 days old and were examined monthly for 1 year. During this period localized alopecia, corneal ulceration, keratitis, strabismus, enophthalmos, ocular atrophy, hemifacial atrophy and slight bone atrophy on the side of the sympathectomy were observed. Thus, cervical sympathectomy reproduces in animals the principal clinical alterations of Romberg's syndrome. Our data suggest that the sympathetic system is involved in the pathogenesis of this syndrome.

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Objective. Juvenile localized scleroderma (JLS) includes a number of conditions often grouped together. With the long-term goal of developing uniform classification criteria, we studied the epidemiological, clinical and immunological features of children with JLS followed by paediatric rheumatology and dermatology centres. Methods. A large, multicentre, multinational study was conducted by collecting information on the demographics, family history, triggering environmental factors, clinical and laboratory features, and treatment of patients with JLS. Results. Seven hundred and fifty patients with JLS from 70 centres were enrolled into the study. The disease duration at diagnosis was 18 months. Linear scleroderma (LS) was the most frequent subtype (65%), followed by plaque morphea (PM) (26%), generalized morphea (GM) (7%) and deep morphea (DM) (2%). As many as 15% of patients had a mixed subtype. Ninety-one patients (12%) had a positive family history for rheumatic or autoimmune diseases; 100 (13.3%) reported environmental events as possible trigger. ANA was positive in 42.3% of the patients, with a higher prevalence in the LS-DM subtype than in the PM-GM subtype. Scl70 was detected in the sera of 3% of the patients, anticentromere antibody in 2%, anti-double-stranded DNA in 4%, anti-cardiolipin antibody in 13% and rheumatoid factor in 16%. Methotrexate was the drug most frequently used, especially during the last 5 yr. Conclusion. This study represents the largest collection of patients with JLS ever reported. The insidious onset of the disease, the delay in diagnosis, the recognition of mixed subtype and the better definition of the other subtypes should influence our efforts in educating trainees and practitioners and help in developing a comprehensive classification system for this syndrome. © 2006 Oxford University Press.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Educação Matemática - IGCE

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Pós-graduação em Educação Matemática - IGCE

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Educação Matemática - IGCE

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Pós-graduação em Educação Matemática - IGCE

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Pós-graduação em Educação Matemática - IGCE

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)