Dor: aspectos atuais da sensibilização periférica e central

JUSTIFICATIVA E OBJETIVOS: As pesquisas recentes têm focalizado a plasticidade bioquímica e estrutural do sistema nervoso decorrente da lesão tissular. Os mecanismos envolvidos na transição da dor aguda para crônica são complexos e envolvem a interação de sistemas receptores e o fluxo de íons intracelulares, sistemas de segundo mensageiro e novas conexões sinápticas. O objetivo deste artigo foi discutir os novos mecanismos que envolvem a sensibilização periférica e central. CONTEÚDO: A lesão tissular provoca aumento na resposta dos nociceptores, chamada de sensibilização ou facilitação. Esses fenômenos iniciam-se após a liberação local de mediadores inflamatórios e a ativação de células do sistema imune ou de receptores específicos no sistema nervoso periférico e central. CONCLUSÕES: As lesões do tecido e dos neurônios resultam em sensibilização de nociceptores e facilitação da condução nervosa central e periférica.

Convergência de linguagens nas artes visuais: cinema, vídeo, teatro e internet

Pós-graduação em Artes - IA

Teologia da Libertação e Cultura Política Maia Chiapaneca: o Congresso Indígena de 1974 e as raízes do Exército Zapatista de Libertação Nacional

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Ethos profissional, hegemonia possível?

Pós-graduação em Serviço Social - FCHS

Clamores da luta pela terra: Igreja e trabalhadores na busca da transformação social

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudos cênicos híbrídos e o corpo em [des]territorialização no processo de urbanização

Pós-graduação em Artes - IA

Vozes de Morazán: mulheres, resistência e organização popular

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Entre vanguarda e a participação: a democracia no programa político da esquerda brasileira (1930-1935)

This paper examines the conceptions of democracy in the Brazilian left among 1930-1935, in particular those expressed in the manifestos of the National Liberative Alliance (ANL) and the texts written by Luis Carlos Prestes, Virgínio Santa Rosa and Caio Prado Jr. I argue that the Brazilian left started from a common troubled field, according to which land concentration represented the biggest obstacle to genuine political expression of the Brazilian people. Despite the convergence towards land reform, designed as a sine qua non condition to democracy in Brazil, the left has developed two different answers to the practical implementation of the principle of the people's government: the first, which I call altruist vanguard, which is more emphasized on texts of Virgínio Santa Rosa and Luís Carlos Prestes, and the second, the Republican participacionismo, which is explored on the writings of Caio Prado Jr. and ambiguously in the manifests of the National Liberative Alliance.

El Salvador: da guerra civil às reformas institucionais dos anos 1990

Pós-graduação em História - FCHS

Karyotype of the invasive species Pterois volitans (Scorpaeniformes: Scorpaenidae) from Margarita Island, Venezuela

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Acupuncture as therapeutic resource in patient with bruxism

Bruxism is the harmful habit of clenching or grinding the teeth during the day and / or night, with unconscious pattern, with particular intensity and frequency, outside the functional movements of chewing and swallowing. It is accepted that bruxism is a response controlled by the neurotransmitters dopamine system associated with emotional component. The proposed of treatment of bruxism with acupuncture aims to stimulate sensory fibers of the peripheral nervous system leading to electrical transmission by neurons sufficient to produce changes in the central nervous system. As a consequence there is the release of substances (cortisol, endorphins, dopamine, noradrenaline and serotonin) that promote wellness and restoration of harmony, be it psychological, biological and / or behavioral.

A crítica da Psicologia e a tarefa da crítica na Psicologia

This article discusses the need to deepen Psychology criticism as a science, unveiling its ideological commitment to the demands posed by the capitalism development and, at the same time, develop the critical thinking in Psychology. Taking the dialectical historical materialism as a basis, the main elements which should be contemplated by the critical thinking are presented: the dialectical reflection; the knowledge criticism; the denounce of degradation, alienation and human heteronomy in the conditions posed by capitalism and the possibility of being used as an instrument in the social transformation process. The incorporation of these elements can guide the constitution process of psychological knowledge which will be able to provide more satisfactory answers to questions concerning the dialectical relationship between individuals and society and the possibilities of human emancipation in nowadays society.

Atuação do interferon-tau no reconhecimento materno da gestação

Maternal recognition of pregnancy is a process by which the conceptus signals its presence to the mother in order to prolong the life of the corpus luteum (CL) thus maintaining the pregnancy. This process occurs between days 15 and 19 after fertilization and is the most important biological challenge for obtaining satisfactory reproductive indices in bovine. Interferon-tau (IFN-τ) glycoprotein -secreted in the uterus by the conceptus- has a paracrine action inhibiting the expression of estrogen receptors (ESR1) and oxytocin (OXTR) in the endometrium, thus preventing the release of luteolytic pulses of prostaglandin F2 alpha (PGF2α), hormone responsible for the onset of luteolysis. IFN-τ also increases the expression of several interferon-stimulated genes (ISGs) in the uterus, CL, and blood cells. Direct endocrine action of IFN-τ on extrauterine tissues stimulates ISGs expression, which in the corpus luteum seems to be involved with luteal resistance to luteolytic action of PGF2α. This review discusses recent findings on the luteolysis mechanism in the bovine and endocrine and paracrine mechanisms such as IFN-τ during the maternal recognition of pregnancy.